Role of bone scanning for evaluation of carcinoma of the cervix.

The value of X-ray studies and bone scan studies of cervix cancer patients was evaluated by a review of patient charts and bone scans or X-ray studies. No in situ cancer patients had positive studies. A low frequency of positive X-ray studies was observed ranging from 1% with stage I to 10% with stage IV disease. Recurrent carcinoma had 10% positive studies. Bone scans correlated well with positive X-ray studies but 10% false-positive scans were seen, mostly osteoarthritis. The bone scan was much more sensitive and appeared to detect an earlier stage lesion, usually associated with symptoms which with radiation and other treatments could follow a more indolent course than the patient with a positive X-ray study. The present study evaluates the appearance and value of these studies, the frequency and circumstances under which useful information was obtained, and what type of survival followed the establishment of the diagnosis.

Value of bone scanning in detecting occult skeletal metastases from adenocarcinoma of the endometrium.

Bone scans were obtained in patients with adenocarcinoma of the uterus in order to search for occult skeletal metastases. Radiological studies in 350 patients with adenocarcinoma of the uterus treated at the University of Kentucky Medical Center were reviewed. All patients studied in Stage 1A, Stage 1BG1, and Stage G2 were negative. Bone scans performed since 1973 were reviewed. One out of 11 patients studied with G3 lesions had a positive scan. Four out of 41 patients with Stage 2 lesions had positive scans, seven out of 18 in Stage 3, and two out of nine in Stage 4 disease. Four out of 71 patients with recurrent tumor had positive scans. In general, all positive scans were associated with significant symptoms in the patients studied. The results correlated well with x-ray findings as evaluated by conventional radiologic studies.