RESUMO
Saim Erkun (1901-1949) was born in Manisa at Aegean region of Anatolia as an Ottoman citizen. While his early life was spent in late Ottoman times at military actions including military prison camp in British colony; India, his active professional productive period was in early Turkish republic period (Est. 1923, centenary). He had a good education period for medicine with the help of his good level of all main World scientific languages such as French, German, and English. Besides his main profession, he was also interested in Ottoman urological medicine around the conquer of Istanbul and allocated them a space in his books in 1930s. He was one of the earliest urology resident (1929-1933, Istanbul) of modern medicine in Turkey. He performed many urological procedures and published the outcomes following modern scientific algorithms, furthermore, there have been urological books including "history" partly referring to antique Ottoman literature among his publications. In this manuscript we focused on the magic word of Urology forever; "Prostate," among his essays. Turkish medicine, particularly urology, renewed itself by some intelligent hard working young clinicians such as Saim Erkun, immediately after the short struggling by means of establishment process of modern Turkiye after World War I by the collapsing of old Ottoman Empire. Furthermore, we think that the stunning special word of urology, "prostate," should especially be mentioned to emphasize the importance of this beginning.
RESUMO
Using phosphodiesterase type 5 (PDE5) inhibitors in patients with lower urinary tract symptoms continues to draw attention. Despite clinical improvements in patients, it is still debatable whether urinary flow rates are increased or not. The aim of this study was to evaluate the acute effects of sildenafil, a PDE5 inhibitor, on uroflowmetry parameters. A total of 110 men who had applied to our outpatient clinics and who had had no history of alpha blocker and PDE5 inhibitor use were included in our study. Two uroflowmetries were performed within 24-72 hours without any treatment. Participants received 50 mg of sildenafil at their third visit, and uroflowmetry was repeated after 2 hours. A total of 102 men were included in the analysis, and baseline uroflowmetry values were compared with values obtained after sildenafil use. The mean age of the 102 participants who had attended all three visits (92.7%) was 52.1 ± 12.2 years. Mean of baseline maximal flow rate values were 17.1 ± 5.1 mL/s, mean of baseline maximal flow rate after sildenafil was 18.2 ± 5.1 mL/s; average flow rate values at the baseline and after sildenafil were 9.5 ± 3.5 and 9.9 ± 3.5 mL/s, respectively. Means of postvoid residual urine volume for baseline and after sildenafil were 31.2 ± 20.1 and 27.7 ± 18.4 mL, respectively. Statistically significant difference is determined between baseline and postsildenafil values in terms of average flow rates at baseline and postvoid residual urine values. Results of this study suggest that sildenafil has an effect on uroflowmetric parameters during an acute period.
