RESUMO
The paper studies electrical activity of the heart during the anti-ischemic protection by cool high-potassium cardioplegic solution based on the blood. Parametres characterising automatism function and the myocardial state of the ventricles practically did not differ from the control data obtained during the experiments without ischemia. Atrioventricular conduction and the atrium myocardium were worse preserved. The positive effects of the papaverine addition to the cardioplegic perfusate has been also shown. The author came to the conclusion that it is necessary to pay special attention to the electrical activity of the supraventricular area of the heart for the adequate evaluation of the cardioplegia.
Assuntos
Doença das Coronárias/prevenção & controle , Coração/fisiopatologia , Animais , Atropina/farmacologia , Doença das Coronárias/fisiopatologia , Cães , Droperidol/farmacologia , Eletrocardiografia , Eletrofisiologia , Coração/efeitos dos fármacos , Parada Cardíaca Induzida/métodos , Técnicas In Vitro , Papaverina/farmacologia , Perfusão/métodos , Promedol/farmacologia , Fatores de TempoRESUMO
In 12 experiments on dogs heterotopic cardiac allotransplantation on the recipient's neck has been performed. During the transplant survival its electrical activity and the coronary blood flow (CBF) were recorded with an implanted sensor of electromagnetic flowmeter. The combination of relatively low CBF and the amplitude of R wave during the first hours after transplantation with a high heart rate is a poor prognostic sign. Oscillations of CBF run parallel to changes of ECG when the viability of the transplant is retained, during the rejection crisis these changes do not correlate. The significance of comprehensive assessment of the cardiac function with the use of ECG and CBF measurement and comparison of their absolute figures and dynamics is shown to be of importance for the early diagnosis of the rejection crisis.