An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic Exercise.

Nanotechnology has widespread applications in sports; however, there are very few studies reporting the use of nanotechnology to enhance physical performance. We hypothesize that a natural-mineral-based novel nanomaterial, which was developed from Japanese hot springs, might overcome the limitations. We examined if it could enhance physical performance. We conducted a treadmill exercise test on 18 students of athletic clubs at Fukushima University, Japan, and measured heart rate, oxygen consumption, maximal oxygen consumption, CO2 production, and respiratory quotient 106 times in total. The results showed that the elevation of heart rate was significantly suppressed in the natural-mineral-based nanomaterial group, while no differences were observed in oxygen consumption, maximal oxygen consumption, CO2 production, and respiratory quotient between groups. To our knowledge, this result is the first evidence where an improvement of cardiovascular and pulmonary functions was induced by bringing a natural-mineral-based nanomaterial into contact with or close to a living body without pharmacological intervention or physical intervention. This could open new avenue of biomedical industries even in an eco-friendly direction. The precise mechanisms remain a matter for further investigation; however, we may assume that endothelial NO synthase, hemoglobin and endothelium-derived hyperpolarizing factor are deeply involved in the improvement of cardiovascular and pulmonary functions.

Longitudinal associations between changes in body composition and changes in sprint performance in elite female sprinters.

It is generally believed that more muscle mass in the lower body reflects more muscular strength and power. If true, greater ground reaction forces may be facilitated from increasing muscle mass, which may result in higher maximal running speeds. One method to assess the potential contributions of body composition (i.e. muscle mass and fat mass) to sprint performance is to examine the associations between those variables within each sprinter across time. The present study examined the relationships between longitudinal changes in body composition and sprint performance. Twelve elite female sprinters (9 of whom participated in the Olympics and/or the World Championships) had total body muscle mass, leg muscle mass, and body fat estimated using ultrasound. For each participant, these measurements lasted at least 5 consecutive years and the longest was 10 consecutive years (average 7 ± 1.5 years). The best sprint time in each season was used for evaluating sprint performance. Our unadjusted model indicated that muscle mass, and body fat correlated favourably with sprint performance over time. After adjusting for the error variance attributable to body fat, the relationship muscle mass with sprint performance is largely eliminated. In the first adjusted model, the partial correlations were r = -0.20 for leg muscle mass and r = 0.46 for body fat. In the second, the partial correlations were r = -0.20 for total muscle mass and r = 0.50 for body fat. In conclusion, these findings may suggest that reducing fat mass may have a greater impact on sprint performance than increasing muscle mass.

Accumulation of Paprika Carotenoids in Human Plasma and Erythrocytes.

The accumulation (incorporation) of paprika carotenoid in human plasma and erythrocytes was investigated. A paprika carotenoid supplement (14 mg/day) was ingested for 4 weeks by 5 young healthy volunteers (3 men and 2 women). After 2 weeks of carotenoid ingestion, the carotenoid levels in plasma and erythrocytes increased by 1.2-fold and 2.2-fold, respectively. Characteristic carotenoids found in paprika (capsanthin, cucurbitaxanthin A, and cryptocapsin) were detected in both plasma and erythrocytes. An oxidative metabolite of capsanthin (capsanthone) was also found in both plasma and erythrocytes.