New Trends of Cervical Cancer Incidence in Kazakhstan.

OBJECTIVE: The epidemiological features of the cervical cancer (CC) incidence and its spatial and temporal assessment in Kazakhstan were studied. METHODS: The retrospective study was done for the period 2009-2018. Descriptive and analytical methods of oncoepidemiology were used. RESULTS: During the study period, 16,441 new cases of CC were registered. The average annual crude and age-standardized incidence rate were 18.6±0.5 and 17.7±0.4 cases per 100,000 population of female, respectively, and their trends tended to increase (Тup=+2.3%; R2=0.708 and Тup=+1.9%; R2=0.615, respectively). The analysis of ASIR showed unimodal growth with a peak at 50-54 years - 45.3±1.1 cases per 100,000 population of female. Trends of ASIR decreased up to 30 years (Tdown=-1.8%; R2=0.111) and 35-59 years (Tdown=-0.9%; R2=0.103), in other age groups the trends increased, and were most pronounced in 40-44 (Тup=+4.1%; R2=0.878) and 65-69 years (Тup=+4.4%; R2=0.537). Trends in ASR of СС tended to grow in almost all regions, with higher levels in Mangystau (Тup=+4.1%; R2=0.482) and Aktobe (Тup=+6.3%; R2=0.846) regions. The cartograms of ASR per 100,000 population of female were allocated according to the following criteria: low - up to 16.3, average - from 16.3 to 19.2, high - above 19.2. The results of the spatial analysis showed the regions with a higher levels of CC incidence rate per 100,000 population of female: East Kazakhstan (19.8), Aktobe (20.0), Almaty (20.1), Kostanay region (20.9), Atyrau (21.7) regions and Almaty city (22.0). CONCLUSION: The study of trends of the cervical cancer incidence has the theoretical and practical value:  monitoring and evaluation of screening programmes, which are implemented in the country, and conduction of secondary prevention of cervical pathology. Health authorities should consider the obtained results in the in the organization of anti-cancer activities.

The ageing rate of workers engaged in chrome ore processing.

BACKGROUND: According to the modern concept of occupational medicine adopted by the World Health Organization, relationship between health and work is fully established while the levels of physical, chemical and biological harmful production factors can be considered as causative factors of occupational diseases. OBJECTIVE: The aim of this research is to determine the aging rate of at risk workers engaged in chrome ore processing in order to increase their health status and quality of life. METHODS: Biological age (BA) of workers was calculated by measuring the blood pressure, static balance (SB), respiratory rate (RR) and by a questionnaire survey on subjective health assessment (SHA). RESULTS: Based on the workplace certification, we have selected unfavorable professions to assess the rate of aging. We have determined the aging rate, according to which biological age exceeds the official age of workers engaged in chrome ore processing in harmful working conditions. CONCLUSIONS: In harmful working conditions, the aging rate accelerates manifesting in at risk worker's health status with BA-PBA ratio in the range from 2.6 to 7.9 years. Regulators, crusher attendants and refractory men, who work in unfavorable climate, should be the leading professional occupations in terms of proper biological age (PBA) monitoring.