Translation and validation of the multiple sclerosis walking scale 12 for the German population - the MSWS-12/D.

BACKGROUND: Gait impairment is a relevant problem in persons with multiple sclerosis (pwMS). The Multiple Sclerosis Walking Scale 12 (MSWS-12) is a valid Patient Reported Outcome Measure (PROM) to evaluate walking ability in pwMS. The aim of this study was to provide a linguistically valid translation of MSWS-12 into German language (MSWS-12/D) and to evaluate its psychometric properties. METHODS: The MSWS-12 was translated in a process modified from guidelines for the cross-cultural adaption of PROMs, and a pre-test was applied in a small sample of 20 pwMS to evaluate comprehensibility and acceptance. Psychometric properties (floor and ceiling effects, internal consistency, construct validity) were then assessed in 124 pwMS seen at academic MS centers. Construct validity was evaluated against Expanded Disability Status Scale (EDSS) and maximum gait speed in the Timed 25-Foot Walk (T25FW). RESULTS: Although the sample covered a wide spectrum of symptom severity, the majority had rather low levels of disability (EDSS median 2.0) and 6.5% scored EDSS of 0. In this sample, MSWS-12/D showed floor effects (36% with score 0) and for internal consistency, a Cronbach's alpha of 0.98 was calculated. MSWS-12/D score showed a relevant correlation to EDSS (ρ = 0.73) and T25FW speed (r=-0.72). CONCLUSION: We provide MSWS-12/D as a linguistically valid German version of MSWS-12. Psychometric properties (acceptance, floor and ceiling effects, internal consistency and construct validity) in pwMS were similar to those described for the original version. This indicates that MSWS-12/D can be applied as equivalent to the original version in German speaking pwMS. Results support the relevance of PROMs to capture patient perception of walking ability in addition to performance-based assessments such as maximum walking speed or maximum walking distance.

Developing a fall prevention program: what are the views and opinions of people with multiple sclerosis?

PURPOSE: Falls are common in people with multiple sclerosis (MS), yet there are a few targeted fall prevention programs. Existing programs report a high dropout rate and a low adherence, which may be due to a mismatch between program characteristics and participants preferences. To clarify a possible discrepancy, this study investigates the views and opinions of persons with MS on fall prevention programs. METHODS: Two focus groups (n = 11) were conducted with people with MS who have a history of falls, near falls or who are concerned about their balance/falling risk. The data were analyzed using a qualitative content analysis with an inductive approach. RESULTS: Participants preferred short-term programs taking place in rehabilitation clinics, or physiotherapy or occupational therapy practices. They believed that the awareness for fall prevention needs to be raised among healthcare professionals. Participants expected better consultation from physio and occupational therapists regarding mobility aids and home modification. The participants wanted the programs to be practical, in-person and in groups. Online interventions were strongly rejected. Further, participants wanted balance/strength exercises and the inclusion of falling techniques in programs. The competence of knowing and accepting capacity may be an important factor in preventing falls. CONCLUSIONS: Investigating the views and opinions of persons with MS on fall prevention programs gave important information which can be used to inform the development of such programs.IMPLICATIONS FOR REHABILITATIONPeople with multiple sclerosis (MS) prefer short-term fall prevention programs that are practical, in-person and in groups. Online interventions were strongly rejected.People with MS want balance/strength exercises and falling techniques included within fall prevention programs.People with MS believe that awareness regarding falls prevention needs to be raised among healthcare professionals. Also, services regarding mobility aids and home modification from physio and occupational therapists are currently unsatisfactory.People with MS believe that competence in knowing and accepting their capacity to engage in activities may be a decisive factor in preventing falls.