[Influence of the medial raphe nucleus damage on discharge activity of the central and bazolateral nuclei of the amygdala]. / Vliianie razrusheniia medial'nogo iadra shva na fonovuiu impul'snuiu aktivnost' neironov tsentral'nogo i bazolateral'nogo iader mindaliny.

It has been revealed pronounced differences between neuronal discharge activity of central and basolateral nuclei of amygdala. After midbrain raphe medial nucleus damage discharge activity of amygdalar nuclei markedly changes, mainly by reciprocal manner. It is suggest that serotonergic afferentations from nucleus raphe to show various influence upon discharge activity of central and lateral nuclei of amygdala.

[Taurine effects on background impulse activity of the internal geniculate body neurons and mesencephalic inferior tubers of white rats]. / Vliianie taurina na fonovuiu impul'snuiu aktivnost' neironov vnutrennogo kolenchatogo tela nizhnikh bugrov chetverokholmiia belykh krys.

Microelectrophysiological and computer techniques were used in the study of background impulse activity (BIA) of the internal geniculate body (IGB) neurons and mesencephalic inferior tubers (MIT) of white rats. Definite differences were found in BIA by regularity, dynamic types and modality of interimpulse histograms. Mean frequency of MIT neuron discharges was 16-17 Hz and was about 3 times higher than in neurons of the IGB. Intraperitoneal injection of taurin noticeably suppressed neuronal activity in both nuclei. The drug reduced mean frequency of background impulse discharges both in MIT and IGB. Thus, taurin produces primarily suppressing modulating effect on neuronal activity of IGB and MIT.

[Spontaneous unit activity of locus coeruleus neurons after destruction of some nuclei of the medulla oblongata]. / Fonovaia impul'snaia aktivnost' neironov golubogo piatna krysy posle razrusheniia nekotorykh iader prodolgovatogo mozga.

Bilateral lesions of the nuclei prepositus hypoglossi produced a more than twofold decrease in the mean frequency discharges in the neurons of the nucleus coeruleus. The number of neurons with burst activity and the number of polymodal neurons substantially increased. Lesion of the nucleus tractus solitarius resulted in an increase in the number of neurons with regular activity and certain decrease in the mean discharge frequency of coeruleus neurons. The results confirm the suggestion about a substantial role of the nucleus prepositus hypoglossi in relaying afferent effects to the activity of locus coeruleus neurons.

[Qualitative and quantitative changes in phospholipid spectra of the brain of rats with corazol-induced epilepsy]. / Kachestvennye i kolichestvennye izmeneniia spektra fosfolipidov golovnogo mozga krys pri korazonovykh sudorogakh.

The enhancement of the sum of phospholipids in seizure period was observed during initially generalized corazol seizure in white rats' cerebral cortex. This sum fell in an hour after epileptic fit. It is noted that the maintenance of lysophosphatidylcholines and phosphatidylserines enhanced during the fit, and the maintenance of phosphatidylcholines and phosphatidylethanolamines fell either in cerebral cortex, or in cerebellum. At the same time the enhancement of the mixed fraction of sphingomyelin and phosphatidylinositide level and cardiolipins-1 in the cerebral cortex was observed. The maintenance of the latter in cerebellum fell during an hour after the attack. The quantity of cardiolipins-2 in cerebellum enhanced during the attack. It is suggested that the effect of corazol seizure leads to the enhancement of lisoforms at the expense of the intensification of disintegration of other fractions of lisoforms.

[The effect of stimulation of the raphe nucleus on the electrical activity of the cerebellar nuclei]. / Vliianie stimuliatsii iadra shva na élektricheskuiu aktivnost' iader mozzhechka.

The stimulation of pontine raphe nucleus evoked field potentials in all the cerebellar nuclei in rats. The field potentials were weak in interpositus nucleus. The neuronal reactions in cerebellar nuclei were mainly inhibitory and quite obvious in fastigial and dentate nuclei.

[Electrophysiologic study of locus coeruleus projections to central cerebellar nuclei]. / Elektrofiziologicheskoe issledovanie proektsii golubogo piatna v tsentral'nye iadra mozzhechka.

Evoked potentials (field responses) were recorded in all cerebellar central nuclei after the locus coeruleus stimulation. Most pronounced responses were recorded in the dentate and fastigial nuclei. Study of the spontaneous neuronal activity of the cerebellar nuclei revealed mainly inhibitory responses to the locus coeruleus stimulation. Most significant inhibitory effects were observed in dentate and fastigial nuclei.

[Interaction of adrenergic and serotoninergic mechanisms in modulation of seizure activity of the brain]. / O vzaimodeistvii adrenergicheskikh i serotoninergicheskikh mekhanizmov v reguliatsii sudorozhnoi aktivnosti mozga.

Electrical stimulation of the raphe nuclei and locus coeruleus induces inhibition of the penicillin-induced seizure activity. Adrenoblocking agents facilitate the effects of raphe nuclei on the seizure activity.

[Effect of exogenous DNA on convulsive activity]. / O vliianii ékzogennoi DNK na sudorozhnuiu aktivnost'.

On the corazole model of the experimental epilepsy and epileptiform activity evoked by penicillin application to the cerebral cortex with electroencephalographic registration, it has been shown that exogenous DNAs in the most cases completely or partially inhibit convulsive activity. DNA inhibited also the pacemaker activity of the Helix RPa-1 neurons.