CT protocols and radiation doses for hematuria and urinary stones: Comparing practices in 20 countries.

PURPOSE: Patients with hematuria and renal colic often undergo CT scanning. The purpose of our study was to assess variations in CT protocols and radiation doses for evaluation of hematuria and urinary stones in 20 countries. METHOD: The International Atomic Energy Agency (IAEA) surveyed practices in 51 hospitals from 20 countries in the European region according to the IAEA Technical cooperation classification and obtained following information for three CT protocols (urography, urinary stones, and routine abdomen-pelvis CT) for 1276 patients: patient information (weight, clinical indication), scanner information (scan vendor, scanner name, number of detector rows), scan parameters (such as number of phases, scan start and end locations, mA, kV), and radiation dose descriptors (CTDIvol, DLP). Two radiologists assessed the appropriateness of clinical indications and number of scan phases using the ESR Referral Guidelines and ACR Appropriateness Criteria. Descriptive statistics and Student's t tests were performed. RESULTS: Most institutions use 3-6 phase CT urography protocols (80 %, median DLP 1793-3618 mGy.cm) which were associated with 2.4-4.9-fold higher dose compared to 2-phase protocol (20 %, 740 mGy.cm) (p < 0.0001). Likewise, 52 % patients underwent 3-5 phase routine abdomen- pelvis CT (1574-2945 mGy.cm) as opposed to 37 % scanned with a single-phase routine CT (676 mGy.cm). The median DLP for urinary stones CT (516 mGy.cm) were significantly lower than the median DLP for the other two CT protocols (p < 0.0001). CONCLUSIONS: Few institutions (4/13) use low dose CT for urinary stones. There are substantial variations in CT urography and routine abdomen-pelvis CT protocols result in massive radiation doses (up to 2945-3618 mGy.cm).

Comparison of whole-body MRI with diffusion-weighted imaging and PET/CT in lymphoma staging.

OBJECTIVES: To compare the diagnostic efficiency of whole-body MRI-DWI and PET/CT in lymphoma staging. METHODS: A prospective study enrolled 92 patients with lymphoma. Prior to treatment, all patients underwent whole-body MRI-DWI and PET-CT. The methods' efficiency was compared in the diagnosis of lymph node (LN) and organ involvement, and in determining lymphoma stage. RESULTS: Sensitivity, specificity, and accuracy in the diagnosis of enlarged LN involvement were 98.2%, 99.9%, and 99.3%, respectively, for MRI-DWI, and 99.4%, 100.0%, and 99.8%, respectively, for PET/CT. ROC analysis showed similar methods' efficiency in the diagnosis of enlarged LN involvement (p > 0.06). MRI-DWI and PET/CT sensitivity in the diagnosis of non-enlarged LN involvement was 77.8% and 88.1%, respectively (p < 0.001). MRI-DWI and PET/CT sensitivity, specificity, and accuracy in the diagnosis of lung involvement were 73.3%, 98.7%, 94.6% and 86.7%, 98.7%, 96.7%; spleen involvement 54.8%, 98.3%, 83.3% and 100.0%, 100.0%, 100.0%; bone marrow involvement 87.1%, 96.4%, 93.0% and 64.5%, 87.3%, 79.1%; and all-organ involvement 72.9%, 98.1%, 91.4% and 80.0%, 96.6%, 92.2%, respectively. ROC analysis showed similar methods' efficiency in the diagnosis of lung involvement (р > 0.3), higher for PET/CT in spleen involvement (р < 0.0001), higher for MRI-DWI in bone marrow involvement (р < 0.0008), and similar in all-organ involvement (р > 0.35). MRI-DWI and PET/CT determined the correct lymphoma stage in 79 (86%) patients. CONCLUSIONS: Whole-body MRI-DWI and PET/CT determined the correct lymphoma stage in similar numbers of patients. MRI-DWI can serve as a non-irradiative alternative to PET/CT in lymphoma staging. KEY POINTS: • Whole-body MRI-DWI efficiency compared with that of PET/CT is similar in the diagnosis of enlarged LN involvement, inferior in the diagnosis of non-enlarged LN and spleen involvement, but superior in the diagnosis of bone marrow involvement. • A new efficient MRI-DWI sign for diagnosis of diffuse bone marrow involvement has been proposed, i.e., a diffuse increase in spine signal intensity on high b value DWI images above the kidney parenchyma. • MRI-DWI and PET/CT determined the correct lymphoma stage in similar numbers of patients.

IAEA survey of paediatric computed tomography practice in 40 countries in Asia, Europe, Latin America and Africa: procedures and protocols.

OBJECTIVE: To survey procedures and protocols in paediatric computed tomography (CT) in 40 less resourced countries. METHODS: Under a project of the International Atomic Energy Agency, 146 CT facilities in 40 countries of Africa, Asia, Europe and Latin America responded to an electronic survey of CT technology, exposure parameters, CT protocols and doses. RESULTS: Modern MDCT systems are available in 77 % of the facilities surveyed with dedicated paediatric CT protocols available in 94 %. However, protocols for some age groups were unavailable in around 50 % of the facilities surveyed. Indication-based protocols were used in 57 % of facilities. Estimates of radiation dose using CTDI or DLP from standard CT protocols demonstrated wide variation up to a factor of 100. CTDI(vol) values for the head and chest were between two and five times those for an adult at some sites. Sedation and use of shielding were frequently reported; immobilisation was not. Records of exposure factors were kept at 49 % of sites. CONCLUSION: There is significant potential for improvement in CT practice and protocol use for children in less resourced countries. Dose estimates for young children varied widely. This survey provides critical baseline data for ongoing quality improvement efforts by the IAEA.

IAEA survey of pediatric CT practice in 40 countries in Asia, Europe, Latin America, and Africa: Part 1, frequency and appropriateness.

OBJECTIVE: The purpose of this study was to assess the frequency of pediatric CT in 40 less-resourced countries and to determine the level of appropriateness in CT use. MATERIALS AND METHODS: Data on the increase in the number of CT examinations during 2007 and 2009 and appropriate use of CT examinations were collected, using standard forms, from 146 CT facilities at 126 hospitals. RESULTS: The lowest frequency of pediatric CT examinations in 2009 was in European facilities (4.3%), and frequencies in Asia (12.2%) and Africa (7.8%) were twice as high. Head CT is the most common CT examination in children, amounting to nearly 75% of all pediatric CT examinations. Although regulations in many countries assign radiologists with the main responsibility of deciding whether a radiologic examination should be performed, in fact, radiologists alone were responsible for only 6.3% of situations. Written referral guidelines for imaging were not available in almost one half of the CT facilities. Appropriateness criteria for CT examinations in children did not always follow guidelines set by agencies, in particular, for patients with accidental head trauma, infants with congenital torticollis, children with possible ventriculoperitoneal shunt malfunction, and young children (< 5 years old) with acute sinusitis. In about one third of situations, nonavailability of previous images and records on previously received patient doses have the potential to lead to unnecessary examinations and radiation doses. CONCLUSION: With increasing use of CT in children and a lack of use of appropriateness criteria, there is a strong need to implement guidelines to avoid unnecessary radiation doses to children.