[Quality of life in patients after radical prostatectomy].

According to the literature, after radical prostatectomy the patients had normal micturition and erectile function in 50 and 10-30%, respectively. A total of 647 patients with diagnosis prostatic cancer (PC) stage T1a-T4 were examined in two clinics in 1997-2003. Of them, 43 patients (PC stage T1a-T3a) have undergone retropubic radical prostatectomy (RRP) by a modified nerve-preserving technique (preservation of the urinary bladder neck, puboprostatic joints in prostate size > 60 cm). Preoperative and postoperative examinations for urine continence and erectile function after RRP were made in 20 patients. The proposed operative technique of nerve-preserving RRP preserves urine continence and erectile function in many cases. This improves social adaptation of the patients and extends indications for operative treatment.

[The use of low-molecular heparins in prevention and treatment of thrombotic complications after radical prostatectomy]. / Primenenie nizkomolekuliarnykh geparinov v profilaktike i lechenii tromboticheskikh oslozhnenii posle radikal'noy prostatéktomii.

Effects of low-molecular heparin flaxiparin on prevention of thrombotic complications after radical prostatectomy were studied in two groups of patients with localized forms of prostatic cancer at stages T1c, T2a, T2b and T3a. Group 1 received non-fractionated standard heparin in a dose 5000 units 4 times a day for 10 days. Group 2 was treated with flaxiparin in a dose 0.3 ml (7500 U anti-Xa) twice a day s.c. for 10 days. After therapy no thromboembolic complications were observed. In group 2 removal of the urethral catheter was conducted 4-5 days earlier than in group 1. This reduced hospital stay from 29 to 20 days. Flaxiparin accelerated growing vessels in the zone of urethrourethral or urethrovesical anastomosis resulting in improvement of microcirculation and preventing strictures in the anastomotic zone. Thus, low-molecular heparin prevents thromboembolic complications, reduces hospital stay and duration of rehabilitation after radical prostatectomy.