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1.
Indian J Orthop ; 58(6): 747-754, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38812870

RESUMO

Purpose: This study examines the influence of preoperative fatty infiltration (FI) of the subscapularis tendon (SBS) on outcomes following reverse total shoulder arthroplasty (rTSA) with SBS repair. Methods: A cohort of 161 rTSA patients with SBS repair, followed for a mean of 45.3 months, was divided into three groups based on FI: Group A (intact upper and lower portions, n = 85), Group B (intact lower portions, n = 44), and Group C (fatty infiltrated in both portions, n = 32). The mean age was 74.5 years (range: 65-95). Results: Preoperative FI displayed significant disparity among the groups: Group A (1.18 ± 0.60), Group B (2.95 ± 0.56), and Group C (4.0 ± 0.00) (p < .001). Group A exhibited a more positive trend in activities of daily living, particularly in toileting ability (81% in Group A, 68% in Group B, and 72% in Group C), although without statistical significance (p = 0.220). Complication rates varied: Group A had seven acromial fractures (8%), three cases of instability (3%), and six instances of scapular notching (7%). Group B experienced four acromial fractures (9%) and four cases of scapular notching (9%), while Group C had only one case of scapular notching (3%) (p = 0.733). Conclusion: In cases characterized by favorable preoperative SBS quality, there was an elevation in functional internal rotation (IR) post-surgery, accompanied by an increased incidence of postoperative complications. Hence, careful consideration is advised when determining the necessity for SBS repair. Level of Evidence: Level III, retrospective comparative study.

2.
Indian J Orthop ; 58(1): 48-55, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38161393

RESUMO

Purpose: The purpose is to assess the diagnostic accuracy of a provocative test coined as the 'posterior compression test' (PCT) in those with the suspected posterior labral tear or lesion. Methods: A total of 515 'arthroscopic labral repairs' were identified between April 2013 and September 2020. Excluding those with concomitant shoulder pathologies, and only including those with pre-operative documentation of the PCT and/or the Jerk test, 191 patients were included. For the purposes of the analyses, the patients were divided into 'non-posterior' labral tear group which included the anterior labral tears and/or the superior labral anterior-to-posterior (SLAP) tears, versus 'any posterior' labral tear group which included the isolated posterior labral tears, the SLAP tears with posterior extension and the pan-labral tears. Results: When the PCT was performed for the isolated posterior labral tears, the sensitivity was 92.6% with the specificity of 86.5%. The positive predictive value and negative predictive value were 71.4-97%, respectively. The Jerk test's sensitivity was 77.8% but when the two tests were combined, the sensitivity increased up to 96.3%. The combined sensitivity with the Jerk test was still up to 94.6% with the AUC (area under curve) /ROC (receiver operator characteristic) at 0.855. Low 'false-positive' rate with the PCT was observed when the test was performed for the 'non-posterior' labral group, with the sensitivity of 13.5%. Conclusions: The posterior compression test correlated well with the arthroscopic diagnoses in a subset of patients with suspected posterior labral pathology, possibly by means of direct stimulation. Level of Evidence: III; Diagnostic Study.

3.
Sci Rep ; 13(1): 17462, 2023 10 14.
Artigo em Inglês | MEDLINE | ID: mdl-37838748

RESUMO

Although obesity was once considered protective against osteoporosis, various factors influence the relationship between fat and bone mineral density (BMD). To establish the importance of healthy body composition in decelerating declines in BMD, we conducted a study to compare the association between body fat composition and BMD in Korean adults. Using data collected from the Kangbuk Samsung Health Study from 2012 to 2019, this cohort study compared the incidence of decreased BMD among the following four groups: normal BMI and normal adiposity (NBMI-NA), normal BMI and high adiposity (NBMI-HA), overweight, and obesity. Decreased BMD was defined as a Z-score ≤ - 2.0 in premenopausal women and men < 50 years of age or a T-score < - 1.0 in postmenopausal women and men ≥ 50 years of age. Individuals who were diagnosed with osteoporosis or compression fracture after their second visit were categorized as having decreased BMD. The incidence rate of decreased BMD in the NBMI-NA group was 3.37, and that in the NBMI-HA group was 4.81, which was the highest among all groups. After adjusting for confounding factors, NBMI-HA led to a significantly greater risk of decreased BMD compared to NBMI-NA (HR 1.47; 95% CI 1.09-1.99). Even with a normal BMI, a high BFP was associated with an increased risk of decreased BMD. Therefore, healthy body composition management, not simply BMI, is important in preventing decreased BMD.


Assuntos
Densidade Óssea , Osteoporose , Masculino , Humanos , Adulto , Feminino , Pessoa de Meia-Idade , Índice de Massa Corporal , Estudos de Coortes , Obesidade/epidemiologia , Obesidade/diagnóstico , Osteoporose/epidemiologia , Tecido Adiposo , República da Coreia/epidemiologia
4.
Behav Sci (Basel) ; 13(6)2023 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-37366747

RESUMO

When multiple stimuli are simultaneously presented, they compete against each other to be represented in the capacity-limited visual system. This competition increases as stimulus heterogeneity increases. Given that selective attention is a way to resolve this competition, it has been known that the effect of attention on task performance is magnified as the level of competition increases due to increased stimulus heterogeneity. While previous studies showed that stimulus heterogeneity in a task-irrelevant dimension affects task performance, it remains unknown how this kind of stimulus heterogeneity interacts with visual attention and stimulus-driven competition. Here, we found that the process of searching for a target stimulus among non-targets became inefficient as stimulus heterogeneity in a task-irrelevant dimension increased. The results also showed that the magnitude of the attentional cuing effect could be affected by increased heterogeneity. However, this modulation was dependent on the type of varied feature or task demand. We suggest that increased stimulus heterogeneity in a task-irrelevant dimension would increase stimulus-driven competition, which impoverishes the quality of stimulus representations.

5.
Bone Joint J ; 105-B(6): 663-667, 2023 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-37257863

RESUMO

Aims: The aim of this study was to investigate the outcomes of arthroscopic decompression of calcific tendinitis performed without repairing the rotator cuff defect. Methods: A total of 99 patients who underwent treatment between December 2013 and August 2019 were retrospectively reviewed. Visual analogue scale (VAS) and American Shoulder and Elbow Surgeons (ASES) scores were reviewed pre- and postoperatively according to the location, size, physical characteristics, and radiological features of the calcific deposits. Additionally, the influence of any residual calcific deposits shown on postoperative radiographs was explored. The healing rate of the unrepaired cuff defect was determined by reviewing the 29 patients who had follow-up MRIs. Results: Statistically significant improvement from pre- to postoperation was seen in all VAS and ASES scores for each group, but no statistical differences were seen between the postoperative scores according to the differences in the features of the calcific deposits. When residual calcification was observed postoperatively, the mean ASES and VAS (rest) scores improved significantly to 95.0 (SD 5.6) and 0.0 (SD 0.0), respectively (p = 0.006 and p < 0.001), and did not differ from those who had the complete removal. Of 29 patients who had follow-up MRIs, six (20.7%) showed signs of an interstitial tear. This group's mean postoperative ASES and VAS (rest) scores improved to excellent levels of 96.0 (SD 3.7) and 0.0 (SD 0.0), respectively, and were similar to those of the 23 patients with normal MRI appearances. Conclusion: Arthroscopic removal of calcific deposits without repairing the rotator cuff defect resulted in significant improvement in function and pain level, regardless of the deposit's location, size, type, and whether or not complete excision was achieved. Despite leaving the defects unrepaired, in the limited number of patients with follow-up MRIs, 23 of 29 patients (79.3%) showed good healing, and the rest, who had persistent signs of interstitial defects on the MRIs, still had excellent outcomes. The removal of calcific deposits without repairing the cuff defects provided excellent outcomes.


Assuntos
Lesões do Manguito Rotador , Tendinopatia , Humanos , Lesões do Manguito Rotador/diagnóstico por imagem , Lesões do Manguito Rotador/cirurgia , Estudos Retrospectivos , Resultado do Tratamento , Artroscopia/métodos , Tendinopatia/diagnóstico por imagem , Tendinopatia/cirurgia , Descompressão
6.
Knee Surg Sports Traumatol Arthrosc ; 31(9): 4060-4067, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37226010

RESUMO

PURPOSE: This study aimed at comparing the outcomes of medium- to large-sized rotator cuff repairs performed using the suture bridge technique either with or without tape-like sutures, and single row techniques with conventional sutures. METHODS: A total of 135 eligible patients with medium to large rotator cuff tears were identified and analyzed retrospectively, from 2017 to 2019. Only repairs using all-suture anchors were included in the study. Patients were divided into the following three groups: single-row (SR) repair (N = 50), standard double-row suture bridge (DRSB) repair with conventional sutures (N = 35), and DRSB with tape-like sutures (N = 50). The average postoperative follow-up period was 26.3 ± 9.8 months (range, 18-37). RESULTS: DRSB with tapes had the highest re-tear rate of 16% (8/50), but there was no significant difference with the re-tear rates observed in SR (8%, 4/50) and DRSB with conventional sutures (11.4%, 4/35) (n.s.). DRSB with tapes demonstrated higher rate of type 2 re-tears (10%) compared to type 1 re-tears (6%), but the other two groups showed either similar or higher rates of type 1 re-tears compared to that of type 2. Post-operative functional scores of the three groups improved significantly (all p < 0.05), but the differences between the groups were not statistically significant. CONCLUSIONS: No clinical difference in functional outcomes and re-tear rates were observed in DRSB with tapes when compared with SR and DRSB using the conventional sutures. Tape-like DRSB suture which was expected to be superior by its biomechanical advantage was clinically non-superior to conventional DRSB suture. There were no significant differences in VAS scores and UCLA scores. LEVEL OF EVIDENCE: Level III.


Assuntos
Lesões do Manguito Rotador , Manguito Rotador , Humanos , Manguito Rotador/cirurgia , Âncoras de Sutura , Estudos Retrospectivos , Artroscopia/métodos , Lesões do Manguito Rotador/cirurgia , Ruptura/cirurgia , Técnicas de Sutura , Suturas
7.
Aesthet Surg J Open Forum ; 4: ojac065, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36134172

RESUMO

Background: The thread-lifts have been popularized because they offered minimally invasive procedures of facial rejuvenation, but not evaluated by the objective assessment system. Objectives: The purpose of this study is to evaluate the compartment-specific effects after thread-lifts by the tensiometer and FACE-Q. Methods: Retrospective cohort study was performed on 369 consecutive patients undergoing the thread-lifts with V-Loc devices (n = 173) and the limited scar face lifts (n = 196), with the mean follow-up period of 32.2 ±â€…5.2 months, between January 2014 and December 2015. Two hundred-seventy patients had intraoperative tension measurements performed. In an online survey, the blinded study coordinator registered all data in 12 FACE-Q scales. Results: The average age was 46.0 ±â€…10.1 years. The complication rate was 4.8%. The mean value of the tensions was 9.5 ±â€…1.9 N. Patients were better satisfied with the appearance of their marionette (44.3 ±â€…24.8) lifted by device 3&4 (10.1 ±â€…1.6 N), compared with satisfaction with the appearance of their nasolabial folds (37.9 ±â€…20.7) lifted by device 1&2 (8.7 ±â€…2.1 N). The satisfaction of patients of the 40s and 50s&60s was higher than that of patients of the 20s&30s with decision. The satisfaction of patients undergoing limited scar face lifts was higher than that of patients undergoing thread-lifts with social and psychological functions. Conclusions: The tension measurements correlate with compartment-specific effects and play the same role as the indicator between gravitational and volumetric theories, but the limited effectiveness of thread-lifts was found to look 2.3 years younger during a mean follow-up of 2.5 years.

8.
Tob Induc Dis ; 20: 77, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36118556

RESUMO

INTRODUCTION: Cigarette smoking is suggested to be associated with sleep problems. This study evaluated the quantitative association between urinary cotinine-verified smoking intensity and sleep quality assessed by the Pittsburgh Sleep Quality Index (PSQI). METHODS: This was a cross-sectional study of 189970 participants from the Kangbuk Samsung Health Study recruited between 2016 and 2018. Logistic regression analysis adjusted for covariates was performed to estimate the association between urinary cotinine levels assessed by quartiles and poor sleep quality, defined as global PSQI score >5. RESULTS: The odds ratios (OR) and 95% confidence intervals (CI) for poor sleep quality comparing the highest urinary cotinine quartile to non-smokers were: 1.23 (95% CI: 1.16-1.30) for overall, 1.19 (95% CI: 1.12-1.26) for males, and 1.55 (95% CI: 1.29-1.87) for females. Among self-reported never smokers, cotinineverified smokers had higher odds for decreased sleep quality compared to cotinineverified never smokers with OR of 1.26 (95% CI: 1.08-1.46). CONCLUSIONS: Elevated urinary cotinine levels were associated with poor sleep quality in relatively young and middle-aged South Korean adults. Higher odds for poor sleep quality among cotinine-verified smokers who self-reported as never smokers also demonstrate the value of quantitative measurement of urinary cotinine. Prospective studies are warranted to clarify the cause-effect relationship between smoking and sleep quality.

9.
Tomography ; 8(4): 1781-1790, 2022 07 11.
Artigo em Inglês | MEDLINE | ID: mdl-35894015

RESUMO

The present study investigated the neurocognitive mechanisms underlying smartphone/internet addiction. We tested a specific hypothesis that the excessive, uncontrolled use of smartphones should be related to the ability of controlling attention in a purely endogenous and self-regulatory manner. In an fMRI experiment, in which 43 adults participated, we had participants detect and identify specified target stimuli among non-targets. In some trials, 10 s oddball movies were presented as distractors. While the participants try to filter out the distractors and focus their attention on the main task, the activation profiles of the frontoparietal brain regions were examined. The results showed that the people with a higher risk of being addicted to smartphone use failed to filter out distractors via the endogenous control of attention. The neuroimaging data showed that the high-risk group showed significantly lower levels of activation in the frontopolar cortex (FPC). We conclude that people at a high risk of smartphone addiction have difficulty endogenously shifting their attention from distracting stimuli toward goal-directed behavior, and FPC plays a critical role in this self-regulatory control of attention.


Assuntos
Comportamento Aditivo , Smartphone , Adulto , Comportamento Aditivo/diagnóstico por imagem , Comportamento Aditivo/psicologia , Humanos , Internet , Transtorno de Adição à Internet , Imageamento por Ressonância Magnética
10.
Orthop Surg ; 13(1): 353-359, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33283486

RESUMO

BACKGROUND: Reconstruction intramedullary nail spanning the whole length of the femur has been the gold standard treatment for complete atypical diaphyseal fractures of the femur (ADF). However, in cases of incomplete ADF combined with severe bowing, this approach might have complications and lead to iatrogenic complete fracture. We report two cases of incomplete ADF with severe bowing using a precontoured plate (PCP) after rapid prototyping (RP) of the deformed femurs with three-dimensional printing (3DP) technology. CASE PRESENTATION: Two patients presented with gradually worsening thigh pain, especially during walking. The patients had been using bisphosphonates for 4 and 10 years, respectively. Radiography showed an incomplete fracture in the lateral cortex of the right femur shaft. The lateral bowing angles measured in the affected femurs were 15° and 14°, and the anterior bowing angles were 20° and 16°, respectively. In bone scans, both patients showed hot uptake in the right mid-shaft of the femur. Preoperatively, the affected femur of the patient was reconstructed by 3DP RP using CT, and the plate was bent to the shape of the bone model. The ADF was fixed with a PCP using the minimally invasive plate osteosynthesis technique. Both patients were encouraged to start full weight-bearing and return to their preinjury activity level in daily life immediately after surgery. At 2 years postoperatively, radiography showed healing of the fracture site without recurrence of thigh pain and implant-related problems. CONCLUSION: Although intramedullary nailing is the standard surgical treatment for complete ADF, PCP using 3DP RP could be an effective treatment option for incomplete ADF with severely curved femur.


Assuntos
Placas Ósseas , Diáfises/lesões , Diáfises/cirurgia , Fraturas do Fêmur/cirurgia , Fixação Interna de Fraturas/instrumentação , Impressão Tridimensional , Idoso , Pinos Ortopédicos , Feminino , Humanos , Modelagem Computacional Específica para o Paciente
11.
Hip Pelvis ; 32(2): 78-84, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32566538

RESUMO

PURPOSE: To determine if it is feasible and safe for a surgeon to transition from using the posterolateral approach to direct anterior approach (DAA) by evaluating the first 53 cases of total hip arthroplasty using a DAA. MATERIALS AND METHODS: A retrospective review of 52 patients who underwent THA using a DAA between July 2017 and December 2018. Reasons for THA were: femoral neck fracture (n=34), avascular necrosis (n=13), and arthritis (n=6). The mean age was 70 years old. An assessment of feasibility was made by analyzing mean operative time and blood loss. Cup inclination, anteversion, and leg length discrepancy (LLD) were measured using postoperative radiology. Safety of the DAA was judged using the incidence and nature of all complications. RESULTS: The mean operative time was 112 minutes. 135 minutes for the 1st 10 cases, 100 minutes for 2nd 10 cases, 113 minutes for 3rd 10 cases, 119 minutes for 4th 10 cases, and 91 minutes for the final 13 cases. The mean blood loss was 724 mL. Average cup inclination was 40.27°; 2 cases were out of safety angle. Mean anteversion was 16.18°. No intraoperative fractures or infections were observed. LLD was detected in 3 cases, one of which underwent revision due to walking difficulty. Dislocation occurred in 3 cases, all within the first 20 cases, however, there was no recurrent dislocation. CONCLUSION: DAA for THA was deemed to be feasible and safe based on an assessment of operative time, blood loss and complications.

12.
Alcohol ; 85: 127-133, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-31926928

RESUMO

We aimed to determine the association between alcohol consumption change on fasting serum glucose, insulin resistance, and beta cell function. The study population consisted of 55,858 men from the Kangbuk Samsung Health Study. Participants were divided into non-, light, moderate, and heavy drinkers for each of the first and second health examinations based on a self-reported questionnaire on alcohol consumption. The adjusted mean values for change in fasting serum glucose (FSG), homeostatic model assessment of insulin resistance (HOMA-IR), and beta cell function (HOMA-ß) levels were determined according to alcohol consumption change by linear regression. Compared to sustained initial drinkers, those who increased alcohol intake to moderate (p < 0.001) and heavy (p < 0.001) levels had increased FSG levels. In contrast, reduction in alcohol intake to light levels among initial heavy drinkers was associated with reduced change in FSG levels (p = 0.007) compared to sustained heavy drinkers. No significant associations were observed between changes in alcohol intake with HOMA-IR levels. Compared to sustained light drinkers, those who increased alcohol intake to moderate (p < 0.001) and heavy (p = 0.009) levels had lower increases in HOMA-ß levels. Finally, compared to sustained heavy drinkers, those who reduced alcohol consumption to light levels had greater increases in HOMA-ß levels (p = 0.002). Increases in alcohol consumption were associated with higher blood glucose levels and worsened beta cell function. Heavy drinkers who reduce alcohol intake could benefit from improved blood glucose control via improved beta cell function.


Assuntos
Consumo de Bebidas Alcoólicas/epidemiologia , Glicemia/metabolismo , Resistência à Insulina , Células Secretoras de Insulina/metabolismo , Adulto , Jejum , Humanos , Insulina/sangue , Masculino , República da Coreia/epidemiologia
13.
JMIR Mhealth Uhealth ; 7(3): e11251, 2019 03 07.
Artigo em Inglês | MEDLINE | ID: mdl-30843867

RESUMO

BACKGROUND: The surgical microscope is used primarily for microsurgeries, which are more complicated than other surgical procedures and require delicate tasks for a long time. Therefore, during these surgical procedures, surgeons experience back and neck pain. To solve this problem, new technology, such as wearable displays, is required to help surgeons maintain comfortable postures and enjoy advanced functionality during microsurgery. OBJECTIVE: The objective of this study was to develop a surgical microscope system that would work with wearable devices. It would include a head-mounted display (HMD) that can offer 3D surgical images and allow a flexible and comfortable posture instead of fixed eyepieces of surgical microscope and can also provide peripheral visual field with its optical see-through function. METHODS: We designed and fabricated a surgical microscope system that incorporates a see-through type 3D HMD, and we developed an image processing software to provide better image quality. The usability of the proposed system was confirmed with preclinical examination. Seven ENT (ear, nose, and throat) surgical specialists and 8 residents performed a mock surgery-axillary lymph node dissection on a rat. They alternated between looking through the eyepieces of the surgical microscope and viewing a 3D HMD screen connected to the surgical microscope. We examined the success of the surgery and asked the specialists and residents to grade eye fatigue on a scale of 0 (none) to 6 (severe) and posture discomfort on a scale of 1 (none) to 5 (severe). Furthermore, a statistical comparison was performed using 2-tailed paired t test, and P=.00083 was considered significant. RESULTS: Although 3D HMD case showed a slightly better result regarding visual discomfort (P=.097), the average eye fatigue was not significantly different between eyepiece and 3D HMD cases (P=.79). However, the average posture discomfort, especially in neck and shoulder, was lower with 3D HMD display use than with eyepiece use (P=.00083). CONCLUSIONS: We developed a see-through type 3D HMD-based surgical microscope system and showed through preclinical testing that the system could help reduce posture discomfort. The proposed system, with its advanced functions, could be a promising new technique for microsurgery.


Assuntos
Microscopia/instrumentação , Microcirurgia/instrumentação , Cirurgiões Bucomaxilofaciais/psicologia , Dispositivos Eletrônicos Vestíveis/normas , Adulto , Animais , Astenopia/etiologia , Astenopia/prevenção & controle , Modelos Animais de Doenças , Estudos de Viabilidade , Humanos , Imageamento Tridimensional/instrumentação , Imageamento Tridimensional/métodos , Imageamento Tridimensional/normas , Masculino , Microscopia/normas , Microscopia/estatística & dados numéricos , Microcirurgia/métodos , Cirurgiões Bucomaxilofaciais/estatística & dados numéricos , Ratos , Óculos Inteligentes/normas , Óculos Inteligentes/estatística & dados numéricos , Instrumentos Cirúrgicos/normas , Instrumentos Cirúrgicos/estatística & dados numéricos , Dispositivos Eletrônicos Vestíveis/psicologia , Dispositivos Eletrônicos Vestíveis/estatística & dados numéricos
14.
Sci Rep ; 8(1): 11582, 2018 Jul 27.
Artigo em Inglês | MEDLINE | ID: mdl-30050142

RESUMO

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

15.
Sci Rep ; 8(1): 10748, 2018 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-30013089

RESUMO

We evaluated the prognostic value of BMP-2 expression in prostate cancer tissue via immunohistochemistry in prostate cancer patients. From July 2007 to August 2010, radical prostatectomy specimens from 90 patients with clinically localized prostate cancer (mean age, 62.7 years, mean follow-up 90.4 months) were assessed for BMP-2 expression using immunohistochemistry. We used stepwise multivariate Cox regression models stratified by study to assess the independent effects of the predictive factors and estimated hazard ratios (HRs). There were significant differences in the baseline characteristics of Gleason score (GS) and biochemical recurrence (BCR) between the groups with decreased and normal BMP-2 expression. Univariate analysis revealed GS, T stage (≥T3), and decreased BMP-2 expression as significant predictive determinants of BCR. In addition, GS (7: HR 2.836, p = 0.022; ≥8: HR 3.506, p = 0.048) and decreased BMP-2 expression (HR 2.007, p = 0.047) were significantly correlated with BCR in multivariate analysis. Overall five-year BCR-free survival rates in the group with decreased BMP-2 expression were worse than those in the group with normal expression. Therefore, decreased BMP-2 expression in prostate cancer tissue was correlated with the prognostic factors for BCR-free survival in patients with prostate cancer.


Assuntos
Proteína Morfogenética Óssea 2/metabolismo , Recidiva Local de Neoplasia/diagnóstico , Antígeno Prostático Específico/sangue , Próstata/patologia , Neoplasias da Próstata/patologia , Idoso , Biópsia com Agulha de Grande Calibre , Intervalo Livre de Doença , Seguimentos , Humanos , Imuno-Histoquímica , Masculino , Pessoa de Meia-Idade , Terapia Neoadjuvante , Gradação de Tumores , Recidiva Local de Neoplasia/sangue , Recidiva Local de Neoplasia/patologia , Prognóstico , Próstata/cirurgia , Prostatectomia , Neoplasias da Próstata/sangue , Neoplasias da Próstata/mortalidade , Neoplasias da Próstata/terapia , República da Coreia/epidemiologia , Estudos Retrospectivos , Fatores de Risco , Taxa de Sobrevida
16.
Clin Orthop Surg ; 9(4): 472-479, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29201300

RESUMO

BACKGROUND: The role of ultrasound in the thoracic spine has been underappreciated, partly because of the relative efficacy of the landmark-guided technique and the limitation of imaging through the narrow acoustic windows produced by the bony framework of thoracic spine. The aim of this study was to make a comparison between the 12th rib and the spinous process of C7 as a landmark for effective ultrasound-guided target segment identification in the thoracic spine. METHODS: Ultrasonography of 44 thoracic spines was performed and the same procedure was carried out 1 week later again. The target segments (T3-4, T7-8, and T10-11) were identified using the 12th rib (group 1) or the spinous process of C7 (group 2) as a starting landmark. Ultrasound scanning was done proximally (group 1) or distally (group 2) toward the target transverse process and further medially and slightly superior to the target thoracic facet. Then, a metal marker was placed on the T3-4, T7-8, and T10-11 and the location of each marker was confirmed by fluoroscopy. RESULTS: In the total 132 segments, sonographic identification was confirmed to be successful with fluoroscopy in 84.1% in group 1 and 56.8% in group 2. Group 1 had a greater success rate in ultrasound-guided target segment identification than group 2 (p = 0.001), especially in T10-11 (group 1, 93.2%; group 2, 43.2%; p = 0.001) and T7-8 (group 1, 86.4%; group 2, 56.8%; p = 0.002). The intrarater reliability of ultrasound-guided target segment identification was good (group 1, r = 0.76; group 2, r = 0.82), showing no difference between right and left sides. Ultrasound-guided target segment identification was more effective in the non-obese subjects (p = 0.001), especially in group 1. CONCLUSIONS: Ultrasound-guided detection using the 12th rib as a starting landmark for scanning could be a promising technique for successful target segment identification in the thoracic spine.


Assuntos
Pontos de Referência Anatômicos/diagnóstico por imagem , Vértebras Cervicais/diagnóstico por imagem , Costelas/diagnóstico por imagem , Vértebras Torácicas/diagnóstico por imagem , Ultrassonografia , Adulto , Fluoroscopia , Voluntários Saudáveis , Humanos , Adulto Jovem
17.
PLoS One ; 12(10): e0184506, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29073130

RESUMO

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD), a hepatic manifestation or precursor of metabolic syndrome, may increase nephrolithiasis, a renal manifestation of insulin resistance, but the prospective association between NAFLD and incident nephrolithiasis has not been evaluated. We examined the association of NAFLD with the development of nephrolithiasis in a large cohort of Korean men and women. METHODS: We performed a cohort study of 208,578 Korean adults who underwent a health checkup examination between January 2002 and December 2014 and were followed-up annually or biennially through December 2014. NAFLD was defined as the presence of fatty liver in the absence of excessive alcohol use or other identifiable causes. Fatty liver and nephrolithiasis were determined based on ultrasonographic findings. We used a parametric Cox model to estimate the adjusted hazard ratios (HRs) of nephrolithiasis according to the presence of NAFLD. RESULTS: During 1,054,887.6 person-year of follow-up, 16,442 participants developed nephrolithiasis. After adjusting for age, center, year of screening exam, smoking status, alcohol intake, physical activity, education level, body mass index, history of hypertension and diabetes, HOMA-IR, uric acid and C-reactive protein, male participants with NAFLD had a significantly increased risk of nephrolithiasis than those without NAFLD (adjusted HR 1.17, 95% CI 1.06-1.30). However, no association between NAFLD and nephrolithiasis was observed in women (adjusted HR 0.97, 95% CI 0.81-1.16). CONCLUSIONS: In this large cohort study of young and middle-aged Koreans, NAFLD was significantly associated with an increased incidence of nephrolithiasis in men but not in women.


Assuntos
Nefrolitíase/complicações , Hepatopatia Gordurosa não Alcoólica/complicações , Adulto , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
18.
ACS Appl Mater Interfaces ; 9(38): 33129-33136, 2017 Sep 27.
Artigo em Inglês | MEDLINE | ID: mdl-28872825

RESUMO

Polymer/metal/polymer and polymer/metal/inorganic trilayer-structured transparent electrodes with fluorocarbon plasma polymer thin film heaters have been proposed. The polymer/metal/polymer and polymer/metal/inorganic transparent conducting thin films fabricated on a large-area flexible polymer substrate using a continuous roll-to-roll sputtering process show excellent electrical properties and visible-light transmittance. They also exhibit water-repelling surfaces to prevent wetting and to remove contamination. In addition, the adoption of a fluorocarbon/metal/fluorocarbon film permits an outer bending radius as small as 3 mm. These films have a sheet resistance of less than 5 Ω sq-1, sufficient to drive light-emitting diode circuits. The thin film heater with the fluorocarbon/Ag/SiNx structure exhibits excellent heating characteristics, with a temperature reaching 180 °C under the driving voltage of 13 V. Therefore, the proposed polymer/metal/polymer and polymer/metal/inorganic transparent conducting electrodes using polymer thin films can be applied in flexible and rollable displays as well as automobile window heaters and other devices.

19.
Sci Rep ; 7(1): 1451, 2017 05 03.
Artigo em Inglês | MEDLINE | ID: mdl-28469153

RESUMO

Carbon nanotube/polytetrafluoroethylene composite polymer targets are proposed for use in the fabrication of fluorocarbon thin films using the mid-frequency sputtering process. Fluorocarbon thin films deposited using carbon nanotube/polytetrafluoroethylene composite targets exhibit an amorphous phase with a smooth surface and show a high water contact angle, optical transmittance, and surface hardness. X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy studies reveal that as the carbon nanotube concentration increased in the composite target, a carbon cross-linked structure was formed, which enhanced the film hardness and the modulus of the fluorocarbon thin film. Large-area fluorocarbon thin films with a substrate width of 700 mm were successfully fabricated by a pilot-scale roll-to-roll sputtering system using a carbon nanotube/polytetrafluoroethylene composite target.

20.
Korean J Fam Med ; 37(3): 164-70, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27274387

RESUMO

BACKGROUND: Frailty refers to the loss of physiologic complexity and the associated decline in ability to withstand stressors as one gets older. It is defined as unintentional weight loss, exhaustion, weakness, slow walking speed, and low physical activity. According to several western studies, frailty is associated with cognitive impairment, but there have been few studies about the relationship between frailty and cognitive impairment in Korea. Thus, the purpose of this study is to analyze the relationship between cognition and factors related to frailty such as grip strength, walking speed, physical activity, and depression, among female patients older than 65 in Korea. METHODS: A total of 121 subjects among the outpatients of the department of family medicine at Kangbuk Samsung Hospital who did not meet the exclusion criteria were included in this study. We divided the participants into 2 groups, according to the Korean version of the Montreal Cognitive Assessment (MoCA) score: 1 group with subjects that had normal cognition and the other group with patients that had impaired cognition. A comparison was made between the 2 groups in regards to the factors related to frailty, and we completed equation that predicting cognition from the frailty related factors. RESULTS: Compared with the impaired cognition group, the subjects in the normal cognition group had higher hand strength, and walked faster (P<0.001). There was no statistically significant difference in physical activity between the 2 groups (P=0.19). When multiple linear regression analysis was performed using age, grip strength, and walking speed as the predictor variables and MoCA score as the dependent variable, the regression coefficients were calculated to be: -0.2015, 0.2294, 1.2372, and -0.1436, respectively (P<0.05). CONCLUSION: In Korean female patients who are older than 65 years of age, cognition tends to decline as grip strength decreases, walking speed gets slower, depression becomes more severe, and as age increases.

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