RESUMO
A cross-epidemiologic study concerning cardiovascular risk factors in a random sample population of Mexico City was carried out in 1991 and 1992. Lipoprotein(a) (Lp(a)) levels in 404 men and 311 women aged 20-90 years were determined by enzyme-linked immunoassay on fasting plasma. Men and women showed similar age-adjusted Lp(a) values. For the whole population the median Lp(a) was 6.9 mg/dL and the prevalence of high Lp(a) (> 30 mg/dL) was 14%. Small positive correlations between Lp(a) and plasma cholesterol (rs = 0.16) and low density lipoprotein cholesterol (LDL-C) (rs = 0.21), and a negative one with insulin (rs = -0.13) were found. In a multiple regression analysis, insulin and LDL-C were the variables that best explained the variation of Lp(a) in our sample. Our data show that Lp(a) in our population is similar to that found in other populations. An association of Lp(a) with myocardial infarction was observed (high Lp(a) was seen in 33% of atherosclerotic individuals versus 14% in healthy subjects) but did not reach statistical significance.
Assuntos
Doenças Cardiovasculares/epidemiologia , Lipoproteína(a)/sangue , Adulto , Idoso , Idoso de 80 Anos ou mais , Antropometria , Arteriosclerose/sangue , Arteriosclerose/epidemiologia , Glicemia/análise , Doenças Cardiovasculares/sangue , Estudos Transversais , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Hiperinsulinismo/sangue , Hiperinsulinismo/epidemiologia , Lipídeos/sangue , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Infarto do Miocárdio/sangue , Infarto do Miocárdio/epidemiologia , Fatores de Risco , Fumar/sangue , Fumar/epidemiologiaRESUMO
The present study was done between 1989 and 1991 and performed on 263 children 7 to 9 years of age who lived in Mexico City. The goal was to determine the association between risk factors entering the body through the respiratory or digestive path and lead concentration in deciduous teeth. Exposure to risk factors was surveyed through a questionnaire; lead was determined by atomic absorption spectrophotometry with a graphite oven and reported in microgram Pb/g tooth. Statistical significance was found for the habit of sucking toys OR 4.98 (IC 95% 1.23-28.67), the use of glazed earthenware utensils for the preparation and serving of food and drinks OR 2.47 (IC 0.80-8.47), and the ingestion of tinned food, particularly juices OR 3.31 (IC 1.03-12.50). No positive results were found for risk factors involving the respiratory path. A possible explanation for these results is a different risk level for each of the two paths of access.