RESUMO
Water-distilled essential oils from herbal parts of Micromeria cristata (Hampe) Griseb. subsp. phrygia P. H. Davis (Endemic) (Lamiaceae) collected from three different localities were analyzed by GC-MS. The major component characterized in the three oils was borneol (27-39%). Other main components were determined as camphor (9-15%), caryophyllene oxide (4-6%), and trans-verbenol (4-6%) in the oils. Enantiomeric distributions of borneol and camphor in the oils were determined on a fused silica Lipodex-E capillary column using a multidimensional GC-MS system. The three essential oils and both enantiomers of borneol have been evaluated for their antimicrobial activity. They showed inhibitory effects on Gr (-) and Gr (+) pathogenic microorganisms.
Assuntos
Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Lamiaceae/química , Óleos Voláteis/análise , Óleos Voláteis/farmacologia , Canfanos , Contagem de Colônia Microbiana , Cromatografia Gasosa-Espectrometria de Massas , Testes de Sensibilidade MicrobianaRESUMO
In the course of our continuing work on transformation of monoterpenes by microorganisms, the biotransformation of (+)- and (-)-carvone was carried out. The metabolites formed during microbial transformations were screened using a simple, rapid and efficient technique: Headspace-solid phase microextraction (SPME)/GC-MS. The results as well as the application of this technique are described.
Assuntos
Absidia/metabolismo , Antineoplásicos Fitogênicos/farmacocinética , Cunninghamella/metabolismo , Penicillium/metabolismo , Pseudomonas putida/metabolismo , Terpenos/química , Terpenos/farmacocinética , Antineoplásicos Fitogênicos/química , Biotransformação , Monoterpenos Cicloexânicos , Cromatografia Gasosa-Espectrometria de Massas/métodos , Estrutura Molecular , Monoterpenos , EstereoisomerismoRESUMO
Essential oils from Ferulago asparagifolia Boiss., F. galbanifera (Miller) W. Koch, F. humilis Boiss. (Endemic), F. trachycarpa Boiss. growing in Turkey were evaluated against 15 microorganisms for their antifungal and antibacterial activity using an agar tube dilution and microdilution broth susceptibility assay, respectively. The essential oil compositions were investigated by GC/MS. Inhibitory effects against Escherichia coli, Enterobacter aerogenes, Candida albicans, Gaeumannomyces graminis var. tritici, Sclerotium rolfsii and Fusarium moniliforme were remarkable. Results are discussed in comparison with the chemical composition of the essential oils.
Assuntos
Anti-Infecciosos/química , Antifúngicos/química , Asteraceae/química , Óleos Voláteis/química , Óleos Voláteis/farmacologia , Antibacterianos , Anti-Infecciosos/isolamento & purificação , Anti-Infecciosos/farmacologia , Antifúngicos/isolamento & purificação , Antifúngicos/farmacologia , Bactérias/efeitos dos fármacos , Bactérias/crescimento & desenvolvimento , Fungos/efeitos dos fármacos , Fungos/crescimento & desenvolvimento , Cromatografia Gasosa-Espectrometria de Massas , Testes de Sensibilidade Microbiana , Óleos Voláteis/isolamento & purificação , Especificidade da EspécieRESUMO
Water distilled essential oils of five annual Sideritis species collected from different regions of Turkey were analysed by GC/MS. Results are tabulated and compared with main components of the essential oils of perennial Sideritis species from Turkey.
RESUMO
The essential oils from 19 samples of Satureja cuneifolia that is used as a substitute for thyme in Turkey have been analysed by GC and GC/ MS. The plant materials were collected from different regions of Turkey. The results are presented in a comparative manner. Eleven oil samples were found to be rich in carvacrol (26-72%) while in eight samples thymol (22-58%) was the main constituent.
RESUMO
Taraxasteryl acetate was identified as the major triterpenoid of the ethanolic extract of the root bark of Scolymus hispanicus L. Antispasmodic and spasmogenic effects of the ethanolic extract, its fractions, taraxasteryl acetate, and a fluid extract of this plant were tested on isolated rat ileum preparations. The strong biphasic responses observed suggested a possible lithuretic activity of the compounds and the fractions tested.
RESUMO
Taraxasteryl acetate (1) was identified as the major triterpenoid of the ethanolic extract of the root bark of Scolymus hispanicus L. Antispasmodic and spasmogenic effects of the ethanolic extract, its fractions, taraxasteryl acetate, and a fluid extract of this plant were tested on isolated rat ileum preparations. The strong biphasic responses observed suggested a possible lithuretic activity of the compounds and the fractions tested.