Assuntos
Aciclovir/análogos & derivados , Antivirais/administração & dosagem , Infecções por Citomegalovirus/tratamento farmacológico , Retinite/tratamento farmacológico , Timidina/análogos & derivados , Aciclovir/administração & dosagem , Adulto , Ganciclovir , Humanos , Injeções , Masculino , Timidina/administração & dosagem , Corpo Vítreo , ZidovudinaRESUMO
The clinical and microbiologic features of group A streptococcal bacteremia are described in 40 patients, all of whom were seen between January 1982 and June 1983 and all of whom were intravenous drug abusers. Eleven patients had endocarditis (two with left-sided and nine with right-sided), and 29 patients had bacteremia without endocardial involvement. Twenty-seven of the 29 patients without endocarditis had soft tissue infections, primarily groin abscesses. Constitutional symptoms were more severe in patients with endocarditis. The two patients with left-sided endocarditis died despite antimicrobial therapy; all nine patients with right-sided endocarditis and all 29 patients without endocarditis were cured of their infection. A predominant strain of group A streptococcus was identified by serologic typing, suggesting a common source for these cases.
Assuntos
Sepse/etiologia , Infecções Estreptocócicas/etiologia , Transtornos Relacionados ao Uso de Substâncias/complicações , Adulto , Antibacterianos/uso terapêutico , Endocardite Bacteriana/tratamento farmacológico , Endocardite Bacteriana/etiologia , Endocardite Bacteriana/patologia , Feminino , Febre/etiologia , Sopros Cardíacos , Humanos , Injeções Intravenosas/efeitos adversos , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Sepse/microbiologia , Sepse/patologia , Infecções Estreptocócicas/microbiologia , Infecções Estreptocócicas/patologia , Streptococcus pyogenes/efeitos dos fármacos , Streptococcus pyogenes/isolamento & purificaçãoRESUMO
A case of bacteremia caused by Achromobacter species in an immunocompromised patient is described. The patient responded to antibiotic therapy. Detailed antibiotic susceptibility data are presented.
Assuntos
Alcaligenes/isolamento & purificação , Sepse/microbiologia , Adulto , Alcaligenes/efeitos dos fármacos , Antibacterianos/farmacologia , Combinação de Medicamentos/uso terapêutico , Feminino , Gentamicinas/uso terapêutico , Humanos , Tolerância Imunológica , Sepse/tratamento farmacológico , Sulfametoxazol/uso terapêutico , Trimetoprima/uso terapêutico , Combinação Trimetoprima e SulfametoxazolRESUMO
Acute renal failure occurred during indomethacin therapy in a patient with chronic pyelonephritis. Urinary prostaglandin E2 levels were diminished but returned to normal after discontinuation of drug therapy and recovery of renal function. Prostaglandins may be critical for the integrity of renal function, and the use of prostaglandin inhibitors such as indomethacin and other nonsteroidal anti-inflammatory drugs may be deleterious in patients with underlying renal disease.