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1.
J Hum Hypertens ; 34(11): 795-801, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32020050

RESUMO

Early life prevention of obesity and associated metabolic disease is necessary to address the current obesity epidemic. Latino children have a higher risk of obesity, and associated comorbidities such as hypertension than Caucasian children. This study focuses on perinatal childhood and maternal risk factors associated with prehypertension and hypertension prior to age 9 in an urban Latino cohort. A cohort of low income, US born Latino children (n = 131) in San Francisco was followed from birth. Annual assessments were conducted including child dietary intake, anthropometrics, and blood pressure measurements. Maternal body mass index and depressive symptoms were assessed concurrently. Leukocyte telomere length was assessed at age 4 and 5 in children. Rapid infant weight gain (odds ratio (OR) 7.25, 95% confidence interval (CI) 1.33-39.38) and prenatal maternal clinical depression (OR 6.70 95% CI 1.15-39.16) were associated with prehypertension/hypertension before age 9. Early life obesity and leukocyte telomere length were not associated with childhood hypertension. Rapid infant weight gain and exposure to prenatal maternal depression are predictive of childhood prehypertension/hypertension before age 9 in low income, US-born Latino children. The perinatal period is an important time point to target for prevention of childhood hypertension.


Assuntos
Hipertensão , Obesidade Infantil , Pré-Hipertensão , Peso ao Nascer , Índice de Massa Corporal , Criança , Pré-Escolar , Depressão/diagnóstico , Depressão/epidemiologia , Feminino , Humanos , Hipertensão/diagnóstico , Hipertensão/epidemiologia , Lactente , Obesidade Infantil/diagnóstico , Obesidade Infantil/epidemiologia , Gravidez , Pré-Hipertensão/diagnóstico , Pré-Hipertensão/epidemiologia , Fatores de Risco , Aumento de Peso
2.
J Immigr Minor Health ; 21(1): 89-97, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29397484

RESUMO

Childhood obesity is increasing especially in Latinos and early intervention is essential to prevent later obesity complications. Latino children (n = 201) recruited at two San Francisco hospitals were assessed at birth including infant anthropometrics and feeding practices and followed to age 9 with annual anthropometric assessments. We evaluated the relationship between perinatal risk factors and obesity at age 9 and chronic obesity (obesity at both 5 and 9 years). Higher birthweight [odds ratio (OR) 2.48, 95% confidence interval (CI) 1.06-5.81] and maternal pre-pregnancy body mass index (BMI) (OR 1.09, 95% CI 1.00-1.18) were associated with increased risk for obesity at 9 years. Higher maternal pre-pregnancy BMI (OR 1.10, 95% CI 1.01-1.20) was associated with chronic obesity. Additionally, prenatal depression symptoms were protective (OR 0.33, 95% CI 0.11-0.94) against chronic obesity. We found no association between maternal age and education, exclusive breastfeeding at 4-6 weeks, rapid infant weight gain, and obesity or chronic obesity. Perinatal risk factors for obesity including higher birthweight and maternal pre-pregnancy BMI persisted until age 9, whereas, other variables significant at age 5 in our cohort and other populations including exclusive breastfeeding and rapid infant weight gain were no longer associated with increased risk.


Assuntos
Peso ao Nascer , Hispânico ou Latino/estatística & dados numéricos , Mães/estatística & dados numéricos , Obesidade Infantil/etnologia , Índice de Massa Corporal , Pesos e Medidas Corporais , Aleitamento Materno/etnologia , Criança , Pré-Escolar , Doença Crônica , Estudos de Coortes , Feminino , Humanos , Modelos Logísticos , Masculino , Saúde Mental , Fatores de Risco , São Francisco/epidemiologia , Fatores Socioeconômicos
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