RESUMO
The authors present the problem of the migraine and tension-type headache treatment in the children basing on the questionnaires, carried out among the participants of The Third Polish Days of Children Neurology.
Assuntos
Transtornos de Enxaqueca/tratamento farmacológico , Cefaleia do Tipo Tensional/tratamento farmacológico , Criança , Pré-Escolar , Tratamento Farmacológico/métodos , Humanos , Transtornos de Enxaqueca/diagnóstico , Índice de Gravidade de Doença , Inquéritos e Questionários , Cefaleia do Tipo Tensional/diagnóstico , Fatores de TempoRESUMO
A new iridoid ester glycoside acylated with p-coumaric acid was isolated from the flowers of Verbascum phlomoides, together with one known one, specioside. Caffeic acid esters, verbascoside and forsythoside B were found as minor constituents. A new saponin was also obtained and identified as desrhamnosylverbascosaponin.
Assuntos
Glicosídeos/isolamento & purificação , Plantas/química , Saponinas/isolamento & purificação , Acilação , Ácidos Cumáricos/química , Glicosídeos/química , Estrutura Molecular , Saponinas/químicaRESUMO
Phenylethanoid triglycoside acylated with caffeic acid was isolated from the inflorescences of V, lychnitis and identified as verbascoside 6'-0-beta-D-apiofuranoside (forsythoside B). It has also been found, that forsythoside B is one of the major constituents in the inflorescences of V. lychnitis and V. nigrum, whereas in the flowers of V. phlomoides and V. densiflorum it was hardly detectable.
Assuntos
Anti-Infecciosos/isolamento & purificação , Antineoplásicos Fitogênicos/isolamento & purificação , Glucosídeos/isolamento & purificação , Imunossupressores/isolamento & purificação , Fenóis , Extratos Vegetais/isolamento & purificação , Acetilação , Anti-Infecciosos/química , Antineoplásicos Fitogênicos/química , Antioxidantes/química , Ácidos Cafeicos/química , Glucosídeos/química , Hidrólise , Imunossupressores/química , Espectroscopia de Ressonância Magnética , Metanol/química , Extratos Vegetais/análise , Relação Estrutura-AtividadeRESUMO
Two triterpene saponins have been isolated from the inflorescences of Verbascum nigrum. Their structures were determined by chemical and spectral methods as 3-O-([alpha-L-rhamnosyl-(1-->4)-(beta-D-glucopyranosyl-(1-->3)]-be ta-D-glucopyranosyl]-(1-->2)-beta-fucopyranosyl)-13 beta,28-epoxyolean-11-ene-3 beta,23-diol and 3-O-([alpha-L-rhamnosyl-(1-->4)-(beta-D-glucopyranosyl-(1-->3)-bet a-D- glucopyranosyl]-(1-->2)-beta-fucopyranosyl)-11-methoxy-olean-12-en e-3 beta,23,28-triol.