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Kardiologiia ; 31(4): 59-62, 1991 Apr.
Artigo em Russo | MEDLINE | ID: mdl-1712406

RESUMO

The paper discusses if it is advisable to use kallikrein-kinin system inhibitors earlier. A total of 122 patients with acute ischemia and infarction of the myocardium were studied. Contrykal and heparin infused in the prehospital period, followed by hospital treatment are optimal to prevent vascular wall lesions, maximally retain retrograde blood flow, and substantially reduce the size of myocardial infarction. Therapy with protease inhibitors proved to be most beneficial within the first 2 hours of the disease, as evidenced by a profound improvement in the clinical course of myocardial infarction, a decrease in ECG and precordial mapping signs of ischemia, a positive change in myoglobin and MB creatine phosphokinase levels, and a significant reduction in the rehabilitative period.


Assuntos
Aprotinina/uso terapêutico , Infarto do Miocárdio/tratamento farmacológico , Adulto , Idoso , Aprotinina/administração & dosagem , Ensaios Enzimáticos Clínicos , Quimioterapia Combinada , Eletrocardiografia , Serviços Médicos de Emergência , Heparina/administração & dosagem , Heparina/uso terapêutico , Humanos , Pessoa de Meia-Idade , Infarto do Miocárdio/diagnóstico
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