The first reported values of microplastics in prostate.

BACKGROUND: Microplastics are ubiquitous, widespread environmental pollutants with unavoidable human exposure. Herein, it was aimed to investigate the presence of microplastics in prostate tissue. METHODS: Prostate tissues from 12 patients who underwent Trans Urethral Resection of the Prostate (TUR-P) were analyzed to investigate the presence of microplastics. Initially, the prostate tissues were analyzed for microplastic particles using a light microscope after extraction. Subsequently, the chemical composition of the particles found in the prostate tissues was characterized using Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) spectrophotometry. RESULTS: Microplastic particles of various types were detected in 6 out of 12 patients. All detected plastic particles in this study were microplastics, with sizes below 26 µm in size. These microplastics exhibited different shapes as pellets, spheres or fibers. Overall, among the 12 analyzed prostate tissue samples, four different types of plastic were identified in six samples. The most common type of microplastic detected was Polyamide (Nylon 6), found in samples from three patients. Other detected types, Polypropylene, Polyacrylic Acid and Poly (dimethylsiloxane) were each determined in samples from one patient. CONCLUSIONS: This is the first study to demonstrate the presence of microplastics in prostate tissue, serving as an exploratory investigation, which can trigger further research to validate the results in a larger patient cohort.

A holistic approach to the assessment of heavy metal levels and associated risks in the coastal sediment of Giresun, southeast Black Sea.

A seasonal study was conducted to assess the levels, sources, and potential ecological risks of heavy metals (HM) in coastal sediments along the Giresun Coast, located on the southeast coast of the Black Sea. The mean concentrations of HMs as mg/kg were ranked as Fe (27646.37) > Al (27348.55) > Mn (571.87) > Zn (94.16) > Cr (60.64) > Cu (45.66) > Pb (41.37) > Ni (27.29) > Co (14.47) > As (7.36) > Cd (0.20), respectively. At all stations through the year, Al, Cr, Mn, Fe, Co, and Ni were in "the minimum enrichment" class as evaluated by the enrichment factor (EF). As assessed by the contamination factor (CF), all HM levels except Pb, Fe and Cu were "low" or "moderately polluted" at all stations and seasons. With the exception of Cd levels, all HMs in all seasons and stations pointed out "low ecological risk" according to the ecological risk index (Eri). According to the sediment quality guidelines, Ni, Cu and Pb were observed to pose a high ecological risk to habitat. The combined risk assessment indices pointed out low to moderate ecological risk. The study concluded that the region is subject to minimum anthropogenic disturbances in the aquatic environment.