[Peculiarities of sanitary and epidemiological (preventive) measures aimed at contraction and spread control of Ebola virus disease].

Now the Ebola virus continues to extend in the Western Africa. Cases, including with lethal outcomes are also registered in the countries of Europe and America. The probability of drift of this disease on the territory of the Russian Federation, including through the foreign military personnel who is trained in the country isn't excluded. For prevention of drift and distribution in Russia of the illness caused by the Ebola virus the complex of sanitary and anti-epidemic (preventive) actions is developed and introduced in practice of military health care. The specified actions allow to control an epidemiological situation on this infection and can be recommended for use to military medical experts at all levels.

[Epidemiology and prophylaxis of community-acquired pneumonia in servicemen].

Community-acquired pneumonia is one of the most pressing issues for military medicine in connection with a high incidence among conscripts. After the vaccination beginning in 2002, the uninterrupted increase of the pneumonia incidence that had been observed in 90-th years was changed to the tendency of decrease. But in 2009 and 2010 the incidence of pneumonia increased significantly in all military districts because of crowded conditions of accommodation and activation of "mixing" of personnel in connection with reduction of military service period from 2 and 1.5 years to 1 year. The improvement of accommodation conditions and prevention of excessive cooling are the bases of prevention of pneumonia. It is recommended to use bactericidal air recycling apparatus in barracks. Medicament prophylaxis consists of vaccination with polysaccharide pneumococcal vaccine (Pneumo 23) together with influenza vaccine. It is necessary to approve in the troops conjugate pneumococcal vaccine (Prevenar 13), which was registered in Russia 2 years ago. Vaccination should be combined with the use of immunotropical and antivirus medication, vitamins.

[Spatial distribution of Marmota baibacina and M. sibirica (Marmota, Sciuridae, Rodentia) in a zone of sympatry in Mongolian Altai: bioacoustic analysis].

The spatial distribution of two marmot species Marmota baibacina and M. sibirica in a zone of coexistence was studied by using their alarm call as a diagnostic trait. It was found that M. baibacina prefers to inhabit bouldery screes, whereas M. sibirica inhabits all suitable biotopes. The difference in biotopic distribution of these species could be explained by M. sibirica forcing M. baibacina out of optimum habitats. Cases of coexistence of both species in one family group sites were registered, which might contribute to the appearance of hybrids.

[Treatment of gastric ulcer associated with Helicobacter pylori with ronkoleukine under outpatient conditions].

AIM: To determine clinicoimmunological and microbiological efficacy of ronkoleukine in the treatment of Helicobacter pylori-associated gastric ulcer (GU). MATERIAL AND METHODS: A total of 108 H. pylori-associated GU were randomized into two groups. Patients of group 2 received standard 3 or 4 component therapy including proton pump inhibitor and two antibiotics (amoxicillin and clarithromycin). Patients of group 1 received the same treatment but antibiotics were replaced for recombinant interleukine-2 ronkoleukine (Biotech, Russia) which was delivered via gastroscope and injected submucously along the periphery of the ulcer defect in 4-6 points in a dose 0.1 mg; 0.4 mg of the drug was simultaneously injected intravenously. The procedure was made 3 times with a 72 hour interval. RESULTS: One month after the treatment H. pylori eradication was 81.5 and 95.4% in groups 1 and 2, respectively. Mean duration of ulcer epithelization was 35.23 +/- 1.58 and 10.79 +/- 0.46 days, respectively. CONCLUSION: Clinically and pathogenetically sound method of H. pylori-associated GU with application of systemic and local (paraulcer) immunotropic ronkoleukine therapy is more cost and immunologically effective than standard treatment and can be used both in hospital and outpatient setting.

[Endovascular treatment of subclavian arterial aneurysm using stent graft]. / Lecheniia anevrizmy podkliuchichnoi arterii s pomoshch'iu stent-grafta.

The authors describe a clinical case of successful endovascular treatment of subclavian arterial pseudoaneurysm using the stent graft JOSTENT-GRAFT 48 mm in length and 6 mm in diameter in a 49-year-old patient. The aneurysm developed over a length of 2 years as a result of polytrauma without remarkable circulatory disorders in the distal arterial bed of the upper extremity. Further existence of aneurysm was conjugated with a risk of ischemic or neurologic complications. This observation demonstrates the current potential of roentgenoendovascular surgery allowing to successfully replace the technically difficult and traumatic surgical intervention in the event of formation of pseudoaneurysms by the pulsatory hematoma type.

[Efficacy of anti-inflammatory treatment with benacort in exacerbations of chronic obstructive lung disease]. / Effektivnost' protivovospalitel'nogo lecheniia benakortom bol'nykh khronicheskoi obstruktivnoi bolezn'iu legkikh v period obostreniia.

AIM: To determine a course and prognostic effectiveness of corticosteroid therapy of chronic obstructive pulmonary disease (COPD). MATERIAL AND METHODS: Long-term therapy with broncholytics (berodual) and benacort was given to 25 patients in non-infectious exacerbation, 20 patients received broncholitics of 45 COPD patients with mild and moderate ventilation disorders. Follow-up lasted for 2.5 years. Treatment effectiveness was judged by clinical indices, external respiration function, parameters of systemic immunity, cytogram of induced sputum and concentration of inflammatory markers in the sputum. RESULTS: An immediate effect of two-month therapy with benacort of COPD exacerbations manifested with positive clinical dynamics and relief of endobronchial inflammation. Prognostic efficacy--with a significant reduction of the frequency of COPD exacerbations and of their mean duration more than 3-fold. CONCLUSION: The results of long-term follow-up support validity of inhalation corticosteroids use for eradication and prevention of noninfectious exacerbations of COPD.

[Influence of the dismissed prisoners with pulmonary tuberculosis on the contingents of tuberculosis dispensaries]. / Vliianie bol'nykh tuberkulezom legkikh, osvobodivshikhsia iz mest lisheniia svobody, na kontingenty protivotuberkuleznykh dispanserov.

Individuals become annually free from confinement places, among them 10.3-28.6% are ill with pulmonary tuberculosis. An average of only 35.6% of this contingent are registered at dispensaries in the territories. Their mortality rates within the first year of registration are 2.3 times higher than those registered at dispensaries of these territories. The authors show it necessary to accomplish cooperation between the health care facilities of the Ministry of Health of Russia and those of the Ministry of Justice of Russia.

[Coamoxiclav in the empirical monotherapy in outpatients with community acquired pneumonia]. / Amokcitsillin/klavulanat kaliya v 'empiricheskol monoterapii u ambulatornykh bol'nykh.

Amoxyclav (amoxycillin/potassium clavulanate, A/PC) was used in a dose of 625 mg 3 times a day in the treatment of 68 outpatients at the age of 17 to 88 years (the average age of 49 years) with slight or moderate community-acquired pneumonia. In 49 per cent of the patients the pneumonia developed at the background of concomitant chronic diseases. The positive clinical effect was observed in 94 per cent of the patients. In 76 per cent of them a short-term treatment course of 5 days was sufficient. Before the treatment 91.8 per cent of the isolates proved to be susceptible to A/PC. The pathogen eradication after completion of the treatment was stated in 72 per cent of the cases. Moderate gastrointestinal adverse reactions developed in 4 patients (6 per cent). The results demonstrated high clinical and bacteriological efficacies of A/PC and made it possible to recommend the drug as the 1st class agent for the initial empirical therapy of community-acquired pneumonia in outpatients.

[Medico-social characteristics of migrant pulmonary tuberculosis patients]. / Mekiko-sotsial'naia kharakteristika bol'nykh tuberkulezom legkikh migraantov.

The dispensary records of 5296 pulmonary tuberculosis patients who moved to the Krasnodar Territory during 5 years were analyzed. The excretors were 50.6%; 17.3% (ex-convicts) were registered in a dispensary. This group of patients refused to be on dispensary record more often than other migrants, had difficulties in contacting with medical personnel, more frequently suffered from concurrent alcoholism. Children's infection in these asocial families was 3 times higher than that in socially favourable tuberculosis foci.

[Substantiation of the use of pepsidil in secretory insufficiency of the digestive glands caused by antitubercular drugs]. / Obosnovanie ispol'zovaniia pepsidila pri sekretornoi nedostatochnosti pishchevaritel'nykh zhelez, vyzvannoi protivotuberkuleznymi preparatami.

The experiments on rats were undertaken to study the action of pepsidil to make up for the biosynthesis deficiency of digestive enzymes in the stomach and pancreas caused by antituberculous drugs (methazide + PAS, isoniazid + PAS, isoniazid + rifampicin + ethambutol). It was proved that pepsidil reduced an inhibiting action of antituberculous drugs on the activity of gastroenteric tract proteinases. The given condition should be taken into account when antituberculous treatment is conducted.

[Effect of antitubercular preparations on enzyme activity of erythrocytes]. / Vliianie protivotuberkuleznykh preparatov na aktivnost' nekotorykh fermentov v éritrotsitakh.

It was established experimentally that antituberculous agents (isoniazide, rifampicin, methazid, ethambutol, PAS) and their combination (isoniazide + rifampicin + PAS; isoniazide + PAS; methazid + PAS) inhibit erythrocytic glucoso-6-phosphate-dehydrogenase, glycerophosphate-dehydrogenase. This should be considered in instituting individual antituberculous therapy.