IgG-lambda secreting B-lymphoplasmacytic lymphoma with disseminated cutaneous infiltration: report of a rare case.

We present an 85-year-old female with IgG-lambda lymphoplasmacytic lymphoma (LPL) with disseminated cutaneous infiltration during disease progression, 9 months after initial diagnosis. The patient was voluntarily undertreated, therefore the disease progressed with vast cutaneous involvement. The patient died from severe sepsis and disseminated intravascular coagulation due to acute respiratory bacterial infection, before receiving any kind of treatment.

[Neuroleptic Malignant Syndrome after whithdrawal of anticholinergic agents].

Neuroleptic Malignant Syndrome (NMS) is a rare but a potential lethal condition therefore it always represents a neurological emergency. Although NMS is considered mainly as idiosyncratic complication of antipsychotic medication, isolated reports show that the syndrome can rarely occur due to other causes such as, after abrupt withdrawal of anticholinergics and this was the case that is presented here. The syndrome continious to carry a high mortality rate and its basic management remains risk reduction, early diagnosis and supportive care. Thus, familiarity and vigilance to all known risk factors is considered essential for early diagnosis and intervention, and concequently for the reduction of morbidity and mortality of NMS.