Assuntos
Frequência Cardíaca/fisiologia , Infarto do Miocárdio/fisiopatologia , Antagonistas Adrenérgicos beta/uso terapêutico , Antiarrítmicos/uso terapêutico , Arritmias Cardíacas/tratamento farmacológico , Arritmias Cardíacas/etiologia , Arritmias Cardíacas/fisiopatologia , Sistema Nervoso Autônomo/fisiopatologia , Ritmo Circadiano , Eletrocardiografia Ambulatorial , Exercício Físico/fisiologia , Fibrinolíticos/uso terapêutico , Frequência Cardíaca/efeitos dos fármacos , Humanos , Infarto do Miocárdio/complicações , Infarto do Miocárdio/tratamento farmacológico , Disfunção Ventricular Esquerda/complicações , Disfunção Ventricular Esquerda/tratamento farmacológico , Disfunção Ventricular Esquerda/fisiopatologiaRESUMO
Registration of standard and high-resolution EGCs, echocardiography in 90 ischemic heart disease (IHD) patients on myocardial infarction week 2 to 6 has demonstrated that deterioration of local myocardial contractility and development of left ventricular dilation increase frequency of late ventricular potentials and worsen parameters of high-resolution ECG. Left ventricular dysfunction is associated with defects in autonomic regulation of cardiac activity. Diminished myocardial contractility had no significant effect on dispersion of repolarisation.
Assuntos
Ecocardiografia , Eletrocardiografia , Infarto do Miocárdio/fisiopatologia , Pulso Arterial , Adulto , Idoso , Humanos , Pessoa de Meia-Idade , Contração Miocárdica , Fatores de Tempo , Disfunção Ventricular Esquerda/fisiopatologiaRESUMO
A study of 40 patients with acute myocardial infarction indicates that in those without circulatory insufficiency phynoptin did not reduce cardiac ejection but reduced postloads, energy expenditures and work of the left ventricle myocardium, favoured early stabilization of the cardiovascular system. In cases with cardiac insufficiency phynoptin reduced the contractile capacity of the left ventricle, stasis in the lesser circulation. Associated use of phynoptin and nitrates in acute myocardial infarction with circulatory insufficiency allowed to avoid depressive effect of phynoptin on myocardial contractility and to avoid progression of cardiac insufficiency.
Assuntos
Infarto do Miocárdio/tratamento farmacológico , Verapamil/uso terapêutico , Adulto , Avaliação de Medicamentos , Quimioterapia Combinada , Feminino , Hemodinâmica/efeitos dos fármacos , Humanos , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/fisiopatologia , Nitroglicerina/administração & dosagemRESUMO
The authors give a description of methods of diagnosis and drug optimization of complicated forms of healing of myocardial infarction. It is emphasized that measures of optimization facilitate the clinical course of the disease, reduce the frequency of development of postinfarction aneurysms and further the decrease of lethality.