RESUMO
OBJECTIVE: To determine whether blood glucose values of over 200 mg/dL in the oral glucose tolerance test (OGTT) are associated with pregnancy complications and adverse perinatal outcomes in patients with gestational diabetes mellitus (GDM). METHODS: A retrospective cohort study was performed comparing patients with GDM A1 (diet controlled) that had at least one value of 200 mg/dL or higher in the OGTT, to those who did not. Patients were treated at the diabetes day care clinic of a tertiary medical center between the years 1999 and 2010. Data were available from the computerized perinatal databases. RESULTS: During the study period, 778 women with GDM were treated at the diabetes day care clinic. Of these, 162 had at least one test value of 200 mg/dL or greater. No significant differences regarding maternal and perinatal complications, such as polyhydramnios, macrosomia (birth-weight above 4 kg), shoulder dystocia, low Apgar scores at 5 min (<7) and cesarean section were noted between the groups. CONCLUSIONS: A value of 200 mg/dL or more in the OGTT is not an indicator of perinatal complications.
Assuntos
Glicemia/análise , Diabetes Gestacional/sangue , Adulto , Biomarcadores/sangue , Diabetes Gestacional/diagnóstico , Feminino , Teste de Tolerância a Glucose/normas , Humanos , Valor Preditivo dos Testes , Gravidez , Prognóstico , Valores de Referência , Estudos Retrospectivos , Índice de Gravidade de Doença , Adulto JovemRESUMO
The NavChair Assistive Wheelchair Navigation System [19] is being developed to reduce the cognitive and physical requirements of operating a power wheelchair for people with wide ranging impairments that limit their access to powered mobility. The NavChair is based on a commercial wheelchair system with the addition of a DOS-based computer system, ultrasonic sensors, and an interface module interposed between the joystick and power module of the wheelchair. The obstacle avoidance routines used by the NavChair in conjunction with the ultrasonic sensors are modifications of methods originally used in mobile robotics research. The NavChair currently employs three operating modes: general obstacle avoidance, door passage, and automatic wall following. Results from performance testing of these three operating modes demonstrate their functionality. In additional to advancing the technology of smart wheelchairs, the NavChair has application to the development and testing of "shared control" systems where a human and machine share control of a system and the machine can automatically adapt to human behaviors.
Assuntos
Locomoção , Robótica/métodos , Terapia Assistida por Computador/métodos , Interface Usuário-Computador , Cadeiras de Rodas , Algoritmos , Desenho de Equipamento , Humanos , Reprodutibilidade dos Testes , Robótica/instrumentação , Terapia Assistida por Computador/instrumentaçãoRESUMO
This paper presents a new concept for a travel aid for the blind. A prototype device, called the NavBelt, was developed to test this concept. The device can be used as a primary or secondary aid, and consists of a portable computer, ultrasonic sensors, and stereophonic headphones. The computer applies navigation and obstacle avoidance technologies that were developed originally for mobile robots. The computer then uses a stereophonic imaging technique to process the signals from the ultrasonic sensors and relays their information to the user via stereophonic headphones. The user can interpret the information as an acoustic "picture" of the surroundings, or, depending on the operational mode, as the recommended travel direction. The acoustic signals are transmitted as discrete beeps or continuous sounds. Experimental results with the NavBelt simulator and a portable prototype show that users can travel safely in an unfamiliar and cluttered environment at speeds of up to 0.8 m/s.
Assuntos
Cegueira/reabilitação , Tecnologia Assistiva , Localização de Som , Acústica , Desenho de Equipamento , Humanos , Microcomputadores , Robótica , Processamento de Sinais Assistido por ComputadorRESUMO
cDNA clones of the fish Cyprinus carpio growth hormone (GH) mRNA have been isolated from a cDNA library prepared from carp pituitary gland poly(A)+RNA. The nucleotide sequence of one of the carp GH cDNA clones containing an insert of 1164 nucleotides (nt) was determined. The cDNA sequence was found to encode a polypeptide of 210 amino acids (aa) including a signal peptide of 22 aa and to contain 5' and 3' untranslated regions of the mRNA of 36 and 498 nt, respectively. The carp GH presents a 63% amino acid sequence homology with the salmon GH, has structural features common with other GH polypeptides of mammalian or avian origin and contains domains of conserved sequence near the N- and C-terminal regions. Southern blot hybridization of carp genomic DNA with GH cDNA probes shows the presence of at least two GH-coding sequences in the fish genome.
Assuntos
Carpas/genética , Clonagem Molecular , Cyprinidae/genética , DNA/genética , Hormônio do Crescimento/genética , Precursores de Proteínas/genética , Sequência de Aminoácidos , Animais , Sequência de Bases , Northern Blotting , Southern Blotting , DNA/isolamento & purificação , Genes , Hormônio do Crescimento/biossíntese , Dados de Sequência Molecular , Conformação de Ácido Nucleico , Precursores de Proteínas/biossíntese , RNA Mensageiro/genética , Mapeamento por Restrição , Salmão/genéticaRESUMO
An experimental microcomputer controlled prosthesis is discussed, where knee damping is governed by kinematic signals, picked up from both legs. The control algorithm is based on division of the walking cycle into ten stages; each stage characterized by an appropriate damping level which governs the restraining moment at the knee, as functionally required. Stage identification is carried out by the kinematic inputs. The experimental prosthesis was tested on one amputee, the first author of this paper. The control system was found to be more advantageous than a conventional valve system in significantly reducing hip muscular effort on the prosthetic side. Gait symmetry is also improved.
