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1.
Heliyon ; 8(11): e11814, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-36468135

RESUMO

Safety of passenger road transportation (PRT) is a global problem considered by scientists. The present study is aimed at PRT safety improvement by developing its advanced model with accident risk minimization. Functional Resonance Analysis Method is used to identify factors influencing PRT safety. Accident risk assessment of the combined action of several factors in PRT is based on a phenomenological model. Possible good and bad PRT scenarios were considered differing in the staff professional experience, work shift duration, speed, vehicle service lifetime, and driver's stress load. Method for quantitative assessment of five main functions in PRT with their variability caused by parameters changes was designed. The proposed criteria were used to assess the parameter's deviations from their normative values and determine the major characteristics of each function. The recommendations for monitoring the driver's psychophysiological state at all transportation stages were developed and the relationship of transportation functions characteristics and criteria affecting passenger safety was established. This methodology enables assessing the PRT reliability level at a certain time. The approach allows evaluating the criteria affecting traffic safety, identifying their potential functionally resonant effect for abnormal PRT due to conditional changes; developing mechanisms to reduce accident risks by improving technical and organizational management.

2.
Comput Math Methods Med ; 2015: 142987, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26543492

RESUMO

This paper proposes and analyses a mathematical model for the problem of distribution of a finite number of irradiation sources during radiotherapy in continuous environments to maximize the minimal cumulative effects. A new algorithm based on nondifferentiable optimization techniques has been developed to solve this problem.


Assuntos
Algoritmos , Planejamento da Radioterapia Assistida por Computador/métodos , Biologia Computacional , Simulação por Computador , Humanos , Conceitos Matemáticos , Modelos Biológicos , Neoplasias/radioterapia , Planejamento da Radioterapia Assistida por Computador/estatística & dados numéricos
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