RESUMO
This paper describes the study of the neuroepithelial bodies (NEB) in the lungs of adult healthy Wistar rats (n = 12). Using the immunocytochemical reaction demonstrating synaptophysin, NEB and immunopositive nerve terminals approaching them, were visualized. It was found that NEB were the structures constantly presented in the rat lung. In contrast to the diffuse neuroendocrine elements, NEB are characterized by grouped distribution of cells. It was found that some part of NEB had no efferent innervation.
Assuntos
Pulmão/citologia , Corpos Neuroepiteliais/citologia , Animais , Pulmão/inervação , Pulmão/metabolismo , Corpos Neuroepiteliais/metabolismo , Nervos Periféricos/citologia , Ratos , Ratos Wistar , Sinaptofisina/genética , Sinaptofisina/metabolismoRESUMO
Distribution of iron in the substantia nigra of the human brain (10 men and women aged 27-78 years) was studied using Perls' histochemical method. Iron ions were demonstrated in the nigral neuropil and melanin-containing neurons. For the first time the nuclei of some neurons were found to contain iron accumulations. The intranuclear iron inclusions correspond to the nucleolus according to their sharp outline and sizes. Detection of iron in the neuronal nucleolus may contribute to the understanding of mechanisms of iron neurotoxicity for nigral dopaminergic neurons.
