[Treatment of purulent-inflammatory complications of polytrauma, diabetes, infected pancreonecrosis]. / Lechenie gnoino-vospalitel'nykh oslozhnenii, soprovazhdaiushchikh politravmu, sakharnyi diabet, infitsirovannyi pankreonekroz.

Results of Antilympholin-K3 use in combined treatment of purulent-inflammatory complications in polytrauma, diabetes, infected pancreonecrosis are analysed. Thirty-nine patients aged from 19 to 74 years were treated. Double injection of Antilympholin-K3 enhanced phagocytic activity of neutrophils, phagocytic index, chemiluminescence of mononuclears and neutrophils, immunoglobulins concentration. Positive dynamics in immunological indices is accompanied by improving clinical status, cleaning of postoperative wounds from pus, improving of epithelisation.

[Mast cells as a test of body state during electromagnetic exposure of varying intensity]. / Tuchnye kletki kak test sostoianiia organizma pri élektromagnitnykh vozdeistviiakh raznoi intensivnosti.

Effects of single and repeated exposure of mice, rats, and rabbits in magnetic fields at 50 Hz and 2 kA/m, 16 kA/m, and 32 kA/m on the populations of dermal, intestinal, and popliteal lymph node labrocytes were studied immediately and within one month after exposure. Single exposure in the magnetic fields of 2 kA/m and 16 kA/m for 4 hours did not produce any changes in labrocytes of these organs. Repeated exposure to 2 kA/m, 16 kA/m, and 32 kA/m for 4 hours during 5 days modulated the functional activity of labrocytes in all the organs. More extended (1.5-2 months) repeated exposure to the intensive magnetic field (32 kA/m) stimulated adaptation and regain of labrocyte populations in the dermal and popliteal lymph nodes whereas enhanced secretion, i.e. degranulation of labrocytes persisted in the intestine. Following one month after the 1.5-2-month exposure to 32 kA/m, labrocyte populations were recovered with the maximum effect in the lymph nodes. High magnetic sensitivity of labrocytes revealed in this study can be used as a test of body reactivity and adaptation to this physical agent. Differences in the reactivity of labrocytes of individual organs and species must be taken into account.

[Standardization of electromagnetic fields of 3-30 MHz with reference to the time factor]. / Normierung elektromagnetischer Felder von 3-30 MHz unter Berücksichtigung des Zeitfaktors.

In chronic experiments (4 months) in rabbits, rats, and mice biological effects were investigated from 7 exposure regimen of electromagnetic fields with a frequency of 24 MHz at field strengths of the electric field component of 125, 250, 500, and 1,000 V/m, respectively, and an exposure time of 0.25, 1, and 4 hrs. respectively. The effects on the CNS, the immune and hormone systems, the peripheral blood and on the spermato and embryo genesis were estimated. The results delivered the basis for the introduction of an index. In point of time different limit values are to be determined according to the energetic load. A concrete value for the energetic load 7,200 (V/m)2.h is proposed as maximum allowable field strength of the electric component 300 V/m.

[Selective action of chorionic gonadotropin on lymphocyte subpopulations]. / Izbiratel'noe vliianie khorionicheskogo gonadotropina na subpopuliatsii limfotsitov.

Influence of chorionic gonadotropin on induction and formation of specific T-suppressors, TDTH-effectors and spontaneous killer cells, depending on its doses and schema of injections was studied. It is shown that chorionic gonadotropin has a stimulating effect on precursors of T-suppressors, not affecting the mature specific T-suppressors, causes damage to the TDTH-effectors and spontaneous killer cells, that permits chorionic gonadotropin to be recognized as an immunomodulating agent.

[Effect of extracts of different origin on primary cultures of cells from inbred mice]. / Deistvie ekstraktov razlichnogo proiskhozhdeniia na pervichnye kul'tury kletok inbrednykh myshei.

The effect of allogeneic and syngeneic extracts from inbred male and female mouse spleens on the primary culture of fibroblasts obtained from subcutaneous connective tissue of CBA and C57BL/6j female mouse fetus was studied. Cytotoxic and growth-inhibiting effect on the cultures increased successively in using extracts from the tissues of syngeneic male mice, allogeneic female and male mice. Consequently, an increase in the degree of antigenic differences of the target=cells and extracts led to enhancement of the allogeneic inhibition phenomenon. For the first time it was shown that in the syngeneic system the extracts from male mouse tissues (containing weak H-Y antigen) exerted a cytotoxic action on the inbred female mouse cells, i.e. caused reaction similar to allogeneic inhibition.