Hypertonic saline versus fluid restriction: The pitfalls in managing acute hyponatremia in a patient with long-standing spinal cord injury.

Spinal cord injury-induced hyponatremia is an under-recognized entity, without a mention in the European hyponatremia guidelines. We present a case of a 56-year-old female quadraplegic patient with cervical cord injury, presenting with severe hyponatremia and tonic-clonic seizures. This case highlights the challenges in medical management; action mechanisms are further discussed.

Colesevelam-induced hypoglycaemia in a patient with type 1 diabetes mellitus.

Colesevelam possesses antidiabetic properties, which could potentiate sulphonylurea or insulin-induced hypoglycemia; clinically significant hypoglycemia, as a side effect to bile acid sequestrants, may be under-recognized in clinical practice.