Assuntos
Encefalopatias/diagnóstico , Doenças do Colágeno/diagnóstico , Encefalite/diagnóstico , Adolescente , Adulto , Idoso , Antibacterianos/uso terapêutico , Diagnóstico Diferencial , Encefalite/líquido cefalorraquidiano , Encefalite/etiologia , Endocardite Bacteriana Subaguda/complicações , Endocardite Bacteriana Subaguda/tratamento farmacológico , Feminino , Febre , Humanos , Lúpus Eritematoso Sistêmico/líquido cefalorraquidiano , Lúpus Eritematoso Sistêmico/diagnóstico , Masculino , Pessoa de Meia-Idade , Poliarterite Nodosa/líquido cefalorraquidiano , Poliarterite Nodosa/diagnósticoRESUMO
The CT examinations described demonstrate the incidence of focal defects of cerebral substance corresponding to the aspect of a completed cerebral infarction. Progress of the disease over several years may induce a remarkable, mainly internal and cortical, cerebral atrophy, due to the vascular damage of the brain. That is why it is important to consider the possibility of a collagenous disease, particularly in the case of young patients, when a differential diagnosis is being made on the basis of such findings.
Assuntos
Encefalopatias/diagnóstico por imagem , Doenças do Colágeno/complicações , Tomografia Computadorizada por Raios X , Adolescente , Adulto , Atrofia , Encéfalo/patologia , Encefalopatias/etiologia , Humanos , Lúpus Eritematoso Sistêmico/complicações , Pessoa de Meia-Idade , Poliarterite Nodosa/complicaçõesRESUMO
392 cases of cerebrovascular disturbances in women while taking oral contraceptives are reported since 1962. There has been a remarkable change of the distribution of age among these women. Till 1970 were mostly women involved between the age of 30 and 34 years. Today this type of distribution is no more to be seen because of the growing number of reports about complications in other age-groups. Complications were till 1970 mostly reported in the period from ten days till six months after taking oral contraceptives. The publications of the last three years are showing that many women are involved, who had taken oral contraceptives more than two years. New publications and our own results are showing no changes of the clinical syndromes and of the prognosis. Our investigation shows no decrease in the number of young women suffering of thromboembolic cerebral disorders of unknown aetiology in the last years. In this group is the percentage of the women, which had taken ovulation inhibitors, no reduced. The conception, that there is a connection between oral contraceptives and cerebrovascular occlusions seems more possible as before. Especially attention in prescription of oral contraceptives should be given to the fact of a known predisposition. The rareness of these complications leads to the conclusion that one or more predisponating factors of a nature not yet known have to be existent.
Assuntos
Anticoncepcionais Orais/efeitos adversos , Embolia e Trombose Intracraniana/induzido quimicamente , Adulto , Tronco Encefálico , Trombose das Artérias Carótidas/induzido quimicamente , Artéria Carótida Interna , Cavidades Cranianas , Estrogênios , Feminino , Alemanha Ocidental , Humanos , Embolia e Trombose Intracraniana/epidemiologia , Trombose dos Seios Intracranianos/induzido quimicamente , Fatores de TempoRESUMO
CNS involvement is a rare manifestation of collagen disease. But in three patients with lupus erythematosus (L.E.) the disease was from its onset characterized by CNS signs: epileptic seizures, cerebellar ataxia, and organic psychosis. The combination of epilepsy or organic psychosis with inflammatory joint disease should make one consider L.E. in the differential diagnosis, even if there is no close time relationship between the occurrence of these signs. Muscle biopsy, EEG recordings and CSF examinations may be of diagnostic value in addition to serological and immunological studies.