[The results of a seroepidemiologic study of Newcastle dysentery]. / Rezul'taty seroépidemiologicheskogo izucheniia dizenterii N'iukasla.

Differences in the monthly distribution in the number of seropositive individuals among children and adults in years with different intensity of the epidemic process have been revealed. Immunity in cases of dysentery caused by S. newcastle reflects the yearly and seasonal activation of the epidemic process in this Shigella infection both in children and adults, the seroconversion characteristics observed in the year of a high morbidity level being a more objective criterion indicating the beginning of the activation of the epidemic process in dysentery caused by S. newcastle in comparison with the commonly registered morbidity level.

[The main trends in a diphtheria epidemic process and the potentials for its elimination in a large city]. / Osnovnye tendentsii épidemicheskogo protsessa difterii i vozmozhnosti ee likvidatsii v usloviiakh krupnogo goroda.

In recent years the tendency towards the activation of the epidemic process of diphtheria, i.e. the appearance of cases of diphtheria simultaneously with the increased levels of circulation of toxigenic and nontoxigenic Corynebacterium diphtheriae and with antitoxic immunity characteristics in children and adults constantly remaining low, has been registered. For the effective control of diphtheria, the profound study of such problems as bacterial carriership, antibacterial immunity and the development of supplementary means of specific prophylaxis is necessary.

[Seasonality of Sonne dysentery among organized and unorganized groups of children in years with different morbidity levels]. / Sezonnost' dizenterii Zonne sredi organizovannykh i neorganizovannykh detei v gody s raznymi urovniami zabolevaemosti.

Differences in the monthly distribution of morbidity in Sonne dysentery among children of preschool age in children's institutions and among those not attending such institutions have been revealed. In years characterized by a high morbidity level, the epidemic process develops simultaneously among all children with some prevalence in its activity being observed from January to August among children not attending children's institutions and from September to December among institutionalized children. In years characterized by a low morbidity level, the rise of morbidity among children aged up to 3 years, both seasonal and not connected with the season (in January), is determined by the rise of morbidity among those children who attend children's institutions, while among noninstitutionalized children aged 4-6 years the seasonal rise of morbidity begins and becomes manifest earlier.

[Monthly dynamics of the antitoxic immunity against diphtheria and tetanus and of normal antibodies to fraction I of the plague microbe in adults]. / Pomesiachnaia dinamika antitoksicheskogo immuniteta protiv difterii i stolbniaka i normal'nykh antitel k fraktsii I chumnogo mikroba u vzrosylkh.

Monthly characteristics of antitoxic immunity to diphtheria and tetanus toxoids in 3,334 adults in Ryazan were determined. As a result, the following differences were established: the characteristics of antidiphtheria immunity were somewhat higher in the autumn-winter period and dropped to the minimal level in the winter-spring period; the maximal characteristics of antitetanus immunity clearly coincided with the hot season, its minimal characteristics with the cold season. For the first time the frequency and titers of normal antibodies to fraction I of Pasteurella pestis in humans were determined. Their monthly dynamics proved to be parallel to the curve indicating the characteristics of antitetanus immunity, but on a lower level: 1-10%. The presence of normal antibodies was accompanied by higher titers to tetanus toxoid, but not to diphtheria toxoid. According to the results of earlier studies, normal antibodies were shown to be the sign of homologous reactivity in inbred animals. Our data indicate that these antibodies can serve as the indirect sign of heterologous reactivity in humans.

[Use of data on Shigella contamination and immunity indices for studying the activity of the epidemic process in dysentery]. / Ispol'zovanie dannykh o vysevaemosti shigell i pokazatelei immuniteta s tsel'iu izucheniia aktivnosti épidemicheskogo protsessa pri dizenterii.

The comparative study of the monthly distribution of characteristics indicating the levels of contamination with Sh. sonnei and Sh. flexneri separately, as well as the seasonal dynamics of the corresponding antibodies, in the years with high and low morbidity levels has been made with the use the indirect hemagglutination test. The possibility of using these characteristics for the evaluation of the activity of the epidemic process in dysentery caused by Sh. sonnei is shown.