Differences in anxiety, worry, and perceived stress among naturally cycling women and oral contraceptives users: a cross-sectional study investigating the role of contraceptive types.

The goal of our study was to test whether the types of OC affect the link between anxiety and its main maintenance factors: worry and perceived stress. Women are particularly at risk of being affected by excessive worrying, a core component of generalized anxiety disorder (GAD), and they are twice as likely as men to suffer from GAD. The literature suggests that gonadal hormones and types of oral contraceptives (OC) should be taken into account when exploring anxiety disorders in women, but the precise mechanism of this link remains understudied. We performed an observational cross-sectional study on a sample of 908 women, including 499 women naturally cycling (NC) and 409 taking OC (277 in the anti-androgenic group, 132 in the androgenic group). The participants filled in a battery of online questionnaires. Anxiety positively correlated with worry and perceived stress in the whole sample and in the three groups: androgenic OC, anti-androgenic OC, and NC. There was no significant difference between the groups on all the variables apart from the age of the participants. However, we found that women taking anti-androgenic OC had significantly higher levels of worry than NC women (after controlling for stress and age). The differences in OC types should be taken into account in future studies which might also lead to a better choice of OC based on women's individual needs.

Neural simulation pipeline: Enabling container-based simulations on-premise and in public clouds.

In this study, we explore the simulation setup in computational neuroscience. We use GENESIS, a general purpose simulation engine for sub-cellular components and biochemical reactions, realistic neuron models, large neural networks, and system-level models. GENESIS supports developing and running computer simulations but leaves a gap for setting up today's larger and more complex models. The field of realistic models of brain networks has overgrown the simplicity of earliest models. The challenges include managing the complexity of software dependencies and various models, setting up model parameter values, storing the input parameters alongside the results, and providing execution statistics. Moreover, in the high performance computing (HPC) context, public cloud resources are becoming an alternative to the expensive on-premises clusters. We present Neural Simulation Pipeline (NSP), which facilitates the large-scale computer simulations and their deployment to multiple computing infrastructures using the infrastructure as the code (IaC) containerization approach. The authors demonstrate the effectiveness of NSP in a pattern recognition task programmed with GENESIS, through a custom-built visual system, called RetNet(8 × 5,1) that uses biologically plausible Hodgkin-Huxley spiking neurons. We evaluate the pipeline by performing 54 simulations executed on-premise, at the Hasso Plattner Institute's (HPI) Future Service-Oriented Computing (SOC) Lab, and through the Amazon Web Services (AWS), the biggest public cloud service provider in the world. We report on the non-containerized and containerized execution with Docker, as well as present the cost per simulation in AWS. The results show that our neural simulation pipeline can reduce entry barriers to neural simulations, making them more practical and cost-effective.

Maladaptive task-unrelated thoughts: Self-control failure or avoidant behavior? Preliminary evidence from an experience sampling study.

Introduction: Task-unrelated thoughts (TUT) play an important role in everyday life functioning (e.g., anticipating the future, or providing a mental break). However, TUT might also be maladaptive, impairing cognitive performance emotion regulation, and increasing the risk of psychological disorders. In the present study, we aimed to test how self-reported control over TUT and task valence moderate the link between task difficulty and TUT intensity, testing the context regulation and avoidant alternative hypotheses of TUT occurrence. Method: Forty-nine participants took part in an experience sampling study. They were asked to answer five times a day for 5 days a series of questions assessing the intensity, valence, control over TUT, and their momentary affect along with characteristics of the task they were currently performing. They also filled in trait questionnaires assessing their tendency to daydream, ruminate, and their beliefs on emotions' usefulness and controllability. Results: The results showed that both task difficulty and one's lower control over thoughts along with their interaction significantly increased TUT intensity. Task negative valence significantly predicted TUT intensity and moderated the link between task difficulty and TUT intensity. In addition, the tendency to daydream and beliefs in the controllability of negative emotions affect the relations in this model. Discussion: To the best of our knowledge, this study is the first to provide quantitative evidence from an experience sampling study on the role of the valence of currently performed tasks and beliefs on emotions on TUT intensity. It might be an important indication for research and clinical practice that maladaptive TUT might not be only linked to self-control failure but also to emotion regulation strategies one is using.

Gratitude Can Help Women At-Risk for Depression Accept Their Depressive Symptoms, Which Leads to Improved Mental Health.

Introduction: Gratitude is commonly known as a positive emotion, but it can also be understood as a disposition-one's inherent quality that includes being grateful for the positive aspects of one's life and appreciating altruistic gifts. A growing body of research suggests that having a disposition of gratitude is positively related to wellbeing and psychological adjustment. The present study examined the extent to which acceptance of illness-a measure of adjustment to a distressing condition-mediated relationships between dispositional gratitude and wellbeing among women who had elevated levels of depressive symptoms. Methods: Participants were 131 women who, based on scores on the Center for Epidemiological Studies Depression scale, were at-risk for experiencing clinical depression. Thirty-five of these participants had been diagnosed as depressed at some point in their lives and 96 had not. Participants completed measures of dispositional gratitude, wellbeing, anxiety, and acceptance of illness. Results: Dispositional gratitude was positively correlated with wellbeing and was negatively correlated with depression and anxiety. Dispositional gratitude was also positively correlated with acceptance of illness. Mediational analyses found that acceptance of illness mediated relationships between dispositional gratitude and wellbeing, between dispositional gratitude and anxiety, and between dispositional gratitude and depression. Moreover, such mediation varied as a function of whether women had ever been diagnosed as depressed. Acceptance of illness was related more strongly to wellbeing for women who had been diagnosed as depressed at some time in their lives than it was for women who had never been diagnosed as depressed. Conclusion: Women with elevated depressive symptoms who were more grateful (compared to those who were less grateful) were more accepting of their condition, which was related to increased wellbeing and decreased feelings of depression and anxiety.

Visual strategies of young soccer players during a passing test - A pilot study.

In sports, studies on visual behavior have mostly focused on expert-novice differences during decision making tasks and during aiming tasks. How visual behavior changes during the early stages of skill acquisition however, has hardly been documented. The current study investigated gaze behavior of young soccer players during the execution of a soccer passing task. Gaze behavior of eleven 8- to 10-year-old soccer players was recorded while they performed the Loughborough Soccer Passing Test. Based on their score, participants were then divided into a high performance group (N=5), and a low performance group (N=6). Results showed that the low performance group tended to look more at the ball while they were handling it. These findings suggest that gaze strategies develop alongside technical skills. More insights in the interplay between technical skills and gaze strategies during skill acquisition could lead to improved training methods for young soccer players.

A Grateful Disposition Promotes the Well-Being of Women with Breast Cancer Through Adaptive Coping.

INTRODUCTION: Gratitude has been studied as a disposition that reflects the extent to which people appreciate what they have in life knowing that it has not been given to them forever. Being grateful has been found to promote quality of life, which is why it may be used to cope in difficult times including during breast cancer diagnosis and treatment. METHODS: Dispositional gratitude was examined in relation to the well-being of women with breast cancer. In the current study, 119 women with breast cancer completed questionnaires that measured gratitude, well-being, coping styles, depression, and anxiety. RESULTS: Correlational analyses found that dispositional gratitude was positively correlated with well-being (p < 0.001) and was negatively correlated with depression (p < 0.05) and anxiety (p < 0.05). Gratitude was also positively correlated with the use of task-oriented (p < 0.05) and socially oriented coping (p < 0.01) techniques. Analyses of mediation using PROCESS found that the use of task-oriented and socially oriented coping mediated relationships between gratitude and well-being, between gratitude and anxiety, and between gratitude and depression. CONCLUSION: In terms of application, the present results suggest that among women who have breast cancer, increasing dispositional gratitude may increase adaptive coping, which in turn will increase their well-being.

Mindfulness-based cognitive therapy reduces clinical symptoms, but do not change frontal alpha asymmetry in people with major depression disorder.

OBJECTIVES: Mindfulness-based cognitive therapy (MBCT) has demonstrated to be successful in the reduction of relapse rates in patients with recurrent major depressive disorder (MDD). Little is known if MBCT is effective for treating individuals with current MDD episode and about underlying psychophysiological mechanisms of symptoms reduction. The aim of the present study was to assess effects of MBCT on depressed individuals in terms of reduction of depressive and anxiety symptoms and to evaluate if this therapeutic improvement would be reflected on neurophysiological level by shift in frontal alpha asymmetry (FAA). PARTICIPANTS: We studied 20 individuals with current MDD. DESIGN: Participants were randomly assigned either to waiting list or 8-week MBCT. Before and after the treatment we have assessed depression, anxiety, and FAA in resting-state electroencephalogram (EEG) - an indicator of approach vs. withdrawal-related response dispositions and a vulnerability factor of MDD. RESULTS: In line with previous findings, reduction of depressive and anxiety symptoms, but no change in mean values of FAA in MBCT group was found. CONCLUSIONS: These results provide a support for the beneficial effects of MBCT in current MDD treatment, however, they do not support the hypothesis on alpha asymmetry change as a neural correlate of MDD improvement.

Manifestations of clinical depression in daily life: a daily diary study of descriptions of naturally occurring events.

In the present study, clinically depressed (n = 135) and non-depressed adults (n = 138) described the events that happened to them each day for two weeks, and these descriptions were content analysed. Participants also rated how stressful and how positive each event was. Multilevel analyses found that depressed individuals, compared to the non-depressed, used more negative emotion words and more pronouns and used fewer positive emotion words, and they rated events as more stressful and less positive. Stressfulness of events was positively related to the use of pronouns and negative emotion words and was negatively related to the use of positive emotion words. Relationships between positivity of events and word counts were in the opposite direction. Controlling for stressfulness or positivity of events eliminated differences between the depressed and non-depressed in word use, except for use of other-pronouns words. Compared to the non-depressed, depressed people may either experience a greater number of objectively stressful or less pleasant daily events or perceive naturally occurring daily events as more stressful and less positive, and they describe daily events in ways that are consistent with such differences.

Attention Dynamics During Emotion Recognition by Deaf and Hearing Individuals.

The enhancement hypothesis suggests that deaf individuals are more vigilant to visual emotional cues than hearing individuals. The present eye-tracking study examined ambient-focal visual attention when encoding affect from dynamically changing emotional facial expressions. Deaf (n = 17) and hearing (n = 17) individuals watched emotional facial expressions that in 10-s animations morphed from a neutral expression to one of happiness, sadness, or anger. The task was to recognize emotion as quickly as possible. Deaf participants tended to be faster than hearing participants in affect recognition, but the groups did not differ in accuracy. In general, happy faces were more accurately and more quickly recognized than faces expressing anger or sadness. Both groups demonstrated longer average fixation duration when recognizing happiness in comparison to anger and sadness. Deaf individuals directed their first fixations less often to the mouth region than the hearing group. During the last stages of emotion recognition, deaf participants exhibited more focal viewing of happy faces than negative faces. This pattern was not observed among hearing individuals. The analysis of visual gaze dynamics, switching between ambient and focal attention, was useful in studying the depth of cognitive processing of emotional information among deaf and hearing individuals.

Concrete vs. Abstract Processing in Repetitive Negative Thinking: Distinct Functional Effects on Emotional Reactivity and Attentional Control.

Repetitive negative thinking (RNT) is a transdiagnostic process linked to emotional regulation impairment and involved in mood, anxiety, eating disorders and addictions. Attentional disengagement impairment is one of the factors hypothesized to be responsible for the recurrent and uncontrollable character of RNT. The aim of the present study was to empirically test this hypothesis with evaluation of disengagement from negative and RNT-related stimuli separately. Sixty participants were randomly allocated to one of three experimental conditions: abstract RNT, concrete RNT, and control condition (distraction). The change in their negative affect (PANAS) and their attentional disengagement impairment (exogenous cueing task) were measured. The analysis revealed that participants in abstract RNT condition presented higher emotional reactivity comparing to concrete or distraction conditions. The results indicated no differences between induction conditions in attentional disengagement. However, participants after concrete RNT induction had longer mean response times in exogenous cueing task comparing to control induction suggesting that they detected presented stimuli slower than participants in control condition. The results raised an important, from clinical point of view, question of distinctive impact of two types of RNT on emotional reactivity and attentional processes.

Relationship between alexithymia and variability of blood pressure measured with ABPM in hypertensive patients.

OBJECTIVE: Studies indicates that dysregulation of emotions plays an important role in the etiology of elevated blood pressure (BP). One of the signatures of emotional dysregulation is alexithymia defined as an impaired ability to experience and express emotions. Previous work indicated that primary hypertension (HT) is marked by higher alexithymia, but little research examined the relationship between alexithymia and variability of evaluated BP with 24 h Ambulatory Blood Pressure Monitoring (ABPM) in HT patients. METHOD: Fifty-five participants diagnosed with hypertension and a matched group of thirty-nine healthy participants filled in The Toronto Alexithymia Scale (TAS-20), a clinical-demographic questionnaire, and were assessed with 24 h ABPM. RESULTS: After removing those with white coat HT, as expected, hypertensive individuals had a higher total score and all three alexithymia subscales. Furthermore, alexithymia was positively correlated with average values of systolic BP. CONCLUSION: These findings provided support for the contention that alexithymia is associated with elevated BP, the higher level of alexithymia the higher systolic BP in 24 h BP measurement. Future studies may examine the causal relationship between alexithymia and HT and evaluate the effectiveness of emotional regulation training interventions to reduce BP in people suffering from primary hypertension.

Using a Gratitude Intervention to Improve the Lives of Women With Breast Cancer: A Daily Diary Study.

Gratitude can be understood in two ways: as a state of being grateful for things and people, and as a disposition. Research suggests that focusing on reasons for being grateful promotes various aspects of well-being. The present study examined the effectiveness of a gratitude intervention for women with breast cancer. Each day for 2 weeks, 42 women with breast cancer described their psychological well-being, social support, and coping strategies. Women in the intervention condition reported the reasons why they felt grateful that day. Moreover, all participants took part in a pre-test session where trait measures were taken to control for dispositional differences. Listing the reasons for gratitude led to higher levels of daily psychological functioning, greater perceived support, and greater use of adaptive coping strategies. These results suggest that gratitude interventions may improve the lives of oncological patients.

Attention to negative words predicts daily rumination among people with clinical depression: evidence from an eye tracking and daily diary study.

The present study examined relationships between attention to negative words and daily rumination and daily adjustment in a sample of clinically depressed individuals. We recorded eye movements of 43 individuals diagnosed with major depression while they were freely viewing dysphoric, threat-related, neutral, and positive words. Then, each day for one week, participants provided measures of their daily rumination and psychological adjustment. Multilevel analyses found that attention to dysphoric and threat-related words was positively related to daily rumination and attention to threat-related words was negatively related to daily adjustment. These findings suggest that the impaired ability to disengage from negative words is positively related to rumination in daily life and is negatively related to well-being, as defined in terms of Beck's Triad.

Eye tracking cognitive load using pupil diameter and microsaccades with fixed gaze.

Pupil diameter and microsaccades are captured by an eye tracker and compared for their suitability as indicators of cognitive load (as beset by task difficulty). Specifically, two metrics are tested in response to task difficulty: (1) the change in pupil diameter with respect to inter- or intra-trial baseline, and (2) the rate and magnitude of microsaccades. Participants performed easy and difficult mental arithmetic tasks while fixating a central target. Inter-trial change in pupil diameter and microsaccade magnitude appear to adequately discriminate task difficulty, and hence cognitive load, if the implied causality can be assumed. This paper's contribution corroborates previous work concerning microsaccade magnitude and extends this work by directly comparing microsaccade metrics to pupillometric measures. To our knowledge this is the first study to compare the reliability and sensitivity of task-evoked pupillary and microsaccadic measures of cognitive load.

Chronic Stereotype Threat Is Associated With Mathematical Achievement on Representative Sample of Secondary Schoolgirls: The Role of Gender Identification, Working Memory, and Intellectual Helplessness.

Stereotype threat affects performance in many different groups across many different domains. Despite a large body of experimental research on situational stereotype threat, little attention has been paid to the consequences of repeated experience of stereotype threat. Using structural equation modeling on data from a representative sample of girls from secondary schools, the current research examined the relations of chronic stereotype threat with mathematical achievement, and effectiveness of working memory functions. Moving beyond past theory, this study examined a new mechanism by which chronic stereotype threat decreases school achievement - namely intellectual helplessness. We assumed that repeated experience of stereotype threat works as intellectual helplessness training. After the phase of cognitive mobilization, cognitive exhaustion appears, because the individual has no gain from intense cognitive effort. Corroborating previous research on acute stereotype threat, we demonstrated that chronic stereotype threat is negatively associated with mathematical achievement. Additionally, it was also associated with lower effectiveness of working memory functions, which seems to show depletion of working memory as an effect of chronic stereotype threat. The results also demonstrated that both mediational paths from chronic stereotype threat to mathematical achievement: through working memory depletion and through intellectual helplessness were significant but only for girls that were highly identified with their gender group. In sum, we extended a well-established model of acute stereotype threat to its chronic version and suggested a new mechanism of chronic stereotype threat, which involves intellectual helplessness. Implications for stereotype threat theory and educational practice are discussed.

Positive online attentional training as a means of modifying attentional and interpretational biases among the clinically depressed: An experimental study using eye tracking.

OBJECTIVE: The present study examined the effectiveness of online positive attention bias modification training (ABMT) in inducing positive attention and positive interpretational biases in depressed individuals. METHOD: Clinically depressed individuals (n = 60) were randomly assigned to one of two conditions of 14-day online ABMT. In the positive ABMT condition, a probe replaced positive stimuli in 100% of trials. In the control condition, the probe replaced positive stimuli in 50% of trials. Before and after training, we recorded eye movements during the completion of a Scrambled Sentence Task in which participants created positive or negative sentences. Participants also completed measures of symptoms of depression and anxiety. RESULTS: After training, participants in the positive ABMT condition fixated longer on positive keywords than participants in the control group and experienced a significant reduction in anxiety. CONCLUSION: These findings suggest that positive AMBT can promote positive attention bias among clinically depressed individuals.

Association of anxiety sensitivity-physical concerns and FVC with dyspnea severity in sarcoidosis.

OBJECTIVE: The purpose of the study was to evaluate the relationship of an objective functional lung parameter (FVC) and a subjective psychological factor (physical symptom concerns) with dyspnea in sarcoidosis. Dyspnea constitutes one of the most common and burdensome symptoms in sarcoidosis, yet little is known about its mechanisms and, in particular, psychological. METHOD: A total of 107 hospitalized sarcoidosis patients (Female=50, Mage=45.3years) volunteered to take part in the correlational research study. Participants underwent spirometry and completed the MRC Dyspnea Scale and the Anxiety Sensitivity Index-3 (ASI) questionnaire. Linear hierarchical regression analysis was used to determine the relationship between the studied predictors and dyspnea severity. RESULTS: The best fitting model predicted 18% of variance in dyspnea severity. Physical symptom concerns subscale of ASI (ß=0.24) and FVC (ß=-0.23) were significantly related to dyspnea MRC severity, but only physical concerns remained significantly related to dyspnea when both predictors were in the model. CONCLUSIONS: The current results suggest that both psychological and physiological factors should be taken into account when explaining subjective dyspnea severity in sarcoidosis. More specifically, these findings call for including cognitive vulnerability factors related to anxiety (physical symptom concerns) into the diagnostic procedures and management of dyspnea in sarcoidosis.

It's Greek to me: Domain specific relationships between intellectual helplessness and academic performance.

In a study of the domain specificity of intellectual learned helplessness, we collected data from 376 students in 14 classrooms. We measured feelings of intellectual helplessness for mathematics and language skills, anxiety about performance in each of these domains, and general working memory. Multilevel modeling analyses found that feelings of helplessness in language skills were negatively related to grades in language but were unrelated to grades in mathematics. Similarly, feelings of helplessness in mathematics were negatively related to grades in mathematics but were unrelated to grades in language. Controlling for anxiety or working memory did not change these relationships, nor did they vary across the age of students. The results support conceptualizations in which learned helplessness has a domain specific component.

Reading Function and Content Words in Subtitled Videos.

In this study, we examined how function and content words are read in intra- and interlingual subtitles. We monitored eye movements of a group of 39 deaf, 27 hard of hearing, and 56 hearing Polish participants while they viewed English and Polish videos with Polish subtitles. We found that function words and short content words received less visual attention than longer content words, which was reflected in shorter dwell time, lower number of fixations, shorter first fixation duration, and lower subject hit count. Deaf participants dwelled significantly longer on function words than other participants, which may be an indication of their difficulty in processing this type of words. The findings are discussed in the context of classical reading research and applied research on subtitling.

An experimental study of the influence of limited time horizon on positivity effects among young adults using eye-tracking.

Compared to younger adults, older adults attend more to positive stimuli, a positivity effect. Older adults have limited time horizons, and they focus on maintaining positive affect, whereas younger adults have unlimited time horizons, and they focus on acquiring knowledge and developing skills. Time horizons were manipulated by asking participants (66 young adults, M age = 20.5 yr., SD = 1.2) to think that their lives would end in three years. Some participants focused on what they would do in these three years (life focus), whereas others focused on the fact that they would die in three years (death focus). Attentional biases to facial expressions of happiness, sadness, fear, anger, and disgust were measured. Participants viewed 20 slides including pairings of a happy face with each of the negative emotions. The dependent measure was the relative attention paid to the faces on each slide. Participants in the experimental conditions exhibited a positivity effect compared to participants in the control condition, although some results suggested that this effect was weaker in the death focus condition than in the life focus condition.