[Synthesis and antibacterial activity of new polyfluoro-1,3,5-oxadiazines].

A number of polyfluro-3,6-dihydro-2H-1,3,5-oxadiazines and polyfluoro-4H-1,3,5-oxadiazines was designed. Relationship between their chemical structure and in vitro activity was investigated. The highest activity against grampositive microorganisms was shown by N1,N6-bis-[2,2,6,6-tetrakis(trifluoromethyl)-3,6-dihydro-2H-1,3,5-oxadiazine-4-yl]-1,6-hexane diamine.

[Synthesis of 1-hydroxyalkyl-3-substituted ureas and thioureas as a substrates for alcohol dehydrogenase]. / Sintez 1-gidroksialkil-3-zameshchennykh mochevin i tiomochevin kak substratov alkogol'degidrogenazy.

A series of 1-(2-hydroxyethyl)- and 1-(3-hydroxyethyl)-3-substituted ureas and thioureas were synthesized. 1-(3-Hydroxyethyl)-3-acylthioureas were shown to be specific substrates for alcohol dehydrogenase in vitro.

[Synthesis of uracil and theophylline derivatives and study of their effect on glucose transport in rat hepatic cells]. / Sintez proizvodnykh uratsila i teofillina i issledovanie ikh vliianiia na transport gliukozy v kletki pecheni krys.

A series of uracil and theophyllin derivatives were synthesized. 4-Amino-1,3-dimethyl-5-nonanoylaminouracil displayed the most pronounced effect of the in vitro stimulation of the 2-deoxyglucose transport into hepatic rat cells.