Adsorption of anti-inflammatory and analgesic drugs traces in water on clay minerals.

The aim of this study was to assess the adsorption of four non-steroidal anti-inflammatory drugs (NSAIDs), namely Paracetamol (PRC), Diclofenac (DIC), Ibuprofen (IBU), and Ketoprofen (KET), using both batch and continuous experiments with clay. Various analytical techniques, including XRD, FTIR, SEM coupled to EDX, and Zeta potential, were employed to characterize both raw and calcined clay. XRD and FTIR analyses confirmed the kaolinite nature of the clay. SEM data revealed a lamellar structure formed in the clay after calcination at 550 °C. Adsorption tests were conducted to determine the optimal adsorption conditions. Batch kinetics of adsorption demonstrated rapid adsorption of all four NSAIDs, with the highest adsorption occurring at pH 4 (DIC, IBU, and KET) and pH 6 for PRC, using a concentration of 20 mg L-1 of calcined clay. Additionally, the pseudo-second-order model provided the best fit for all NSAIDs adsorption processes. Maximum adsorption capacities, as determined by the Langmuir model, were 80 mg g-1 for PRC, 238 mg -1g for DIC, 138 mg g-1 for IBU, and 245 mg g-1 for KET. In fixed bed column studies, three dynamic models (Thomas, Adams-Bohart, and Yoon-Nelson) were utilized to describe the breakthrough curves, with linear regression used to identify key characteristics for process design. The fixed bed column adsorption study revealed that DIC exhibited the highest removal efficiency at 98%, while KET, IBU, and PRC were more persistent, with removal efficiencies of 77.1%, 76.7%, and 67.1%, respectively. The Thomas model was deemed appropriate for describing the breakthrough curve. These findings offer valuable insights into the interactions between clay and pharmaceuticals with varying physicochemical properties. They also provide information on the adsorption models, saturation, and adsorption capacities of various pharmaceuticals on natural clays, which can be crucial for further research and environmental remediation efforts.

Water implications in dialysis therapy, threats and opportunities to reduce water consumption: a call for the planet.

Water is a dwindling natural resource, and potable water is wrongly considered an unlimited resource. Dialysis, particularly hemodialysis, is a water-hungry treatment that impacts the environment. The global annual water use of hemodialysis is approximately 265 million m3/yr. In this reference estimate, two-thirds of this water is represented by reverse osmosis reject water discharged into the drain. In this review, we would like to draw attention to the complexity and importance of water saving in hemodialysis. We propose that circular water management may comply with the "3R" concept: reduce (reduce dialysis need, reduce dialysate flow, and optimize reverse osmosis performance), reuse (reuse wastewater as potable water), and recycle (dialysis effluents for agriculture and aquaponic use). Awareness and sustainability should be integrated to create positive behaviors. Effective communication is crucial for water savings because local perspectives may lead to global opportunities. Besides the positive environmental impacts, planet-friendly alternatives may have significant financial returns. Innovative policies based on the transition from linear to circular water management may lead to a paradigm shift and establish a sustainable water management model. This review seeks to support policymakers in making informed decisions about water use, avoiding wasting, and finding solutions that may be planet friendly and patient friendly in dialysis, especially in hemodialysis treatments.

Living membrane bioreactor for highly effective and eco-friendly treatment of textile wastewater.

The treatability of synthetic textile wastewater containing model dyes, such as reactive black and direct black dye (25.0 ± 2.6 mgdye/L), with chemical oxygen demand (COD, 1000 ± 113 mg/L), ammonia­nitrogen (NH3-N, 140 ± 97 mg/L) and sulphate ions (SO42-, 1357 ± 10.86 mg/L) was investigated in this study using an innovative living membrane bioreactor (LMBR) using an encapsulated self-forming dynamic membrane (ESFDM). The key advantage of ESFDMBR is the self-forming of the biological filtering layer protected between two meshes of inert robust and inexpensive material. A laboratory scale bioreactor (BR) equipped with a filtering unit mounting polyester meshes with a pore size of 30 µm, operated at an influent flux of 30 LMH was thus used. After the formation of the biological living membrane (LM), the treatment significantly reduced COD and DOC concentrations to the average values of 34 ± 10 mg/L and 32 ± 7 mg/L, corresponding to reduction efficiencies of 96.0 ± 1.1 % and 94 ± 1.05 %, respectively. Throughout the LMBR operation, the colours were successfully removed from synthetic textile wastewater with an overall removal efficiency of about 85.0 ± 1.8 and 86.0 ± 1.9 % for direct and reactive dyes, respectively. In addition, the proposed system was also found effective in affording removal efficiency of ammonia (NH3) of 97 ± 0.5 %. Finally, this treatment afforded circa 40.7 ± 5.8 % sulphate removal, with a final concentration value of 805 ± 78.61 mg/L. The innovative living membrane, based on an encapsulated self-forming dynamic membrane allows a prolonged containment of the membrane fouling, confirmed by investigating the concentration of membrane fouling precursors and the time-course variations of turbidity and transmembrane pressure (TMP). Those final concentrations of wastewater pollutants were found to be below the limits for admission of the effluents in public sanitation networks in Italy and Tunisia, as representative countries for the regulation in force in Europe and North Africa. In conclusion, due to the low costs of plant and maintenance, the simple applicability, the rapid online implementation, the application of LMBR results in a promising method for the treatment of textile wastewater.

Hazard and health risk assessment of exposure to pharmaceutical active compounds via toxicological evaluation by zebrafish.

The uncontrolled or continuous release of effluents from wastewater treatment plants leads to the omnipresence of pharmaceutical active compounds (PhACs) in the aquatic media. Today, this is a confirmed problem becoming a main subject of twin public and scientific concerns. However, still little information is available about the long-term impacts of these PhACs on aquatic organisms. In this review, efforts were made to reveal correlation between the occurrence in the environment, ecotoxicological and health risks of different PhACs via toxicological evaluation by zebrafish (Danio rerio). This animal model served as a bioindicator for any health impacts after the exposure to these contaminants and to better understand the responses in relation to human diseases. This review paper focused on the calculation of Risk Quotients (RQs) of 34 PhACs based on environmental and ecotoxicological data available in the literature and prediction from the ECOSAR V2.2 software. To the best of the authors' knowledge, this is the first report on the risk assessment of PhACs by the two different methods as mentioned above. RQs showed greater difference in potential environmental risks of the PhACs. These differences in risk values underline the importance of environmental and experimental factors in exposure conditions and the interpretation of RQ values. While the results showed high risk to Danio rerio of the majority of PhACs, risk qualification of the others varied between moderate to insignifiant. Further research is needed to assess pharmaceutical hazards when present in wastewater before discharge and monitor the effectiveness of treatment processes. The recent new advances in the morphological assessment of toxicant-exposed zebrafish larvae for the determination of test compounds effects on the developmental endpoints were also discussed. This review emphasizes the need for strict regulations on the release of PhACs into environmental media in order to minimize their toxicity to aquatic organisms.

Soil contamination by microplastics in relation to local agricultural development as revealed by FTIR, ICP-MS and pyrolysis-GC/MS.

Plastic film mulching and use of wastewaters for irrigation have been common agricultural practices for over half a century in Tunisia, especially in arid regions, resulting in the undesired creation of a pathway for microplastics (MPs) to enter farmland soil. In order to assess the extent and characteristics of soil contamination by MPs in the Moknine province, an area of intensive agricultural practices, 16 farmland soil samples were collected and characterized. The total concentration of targeted MPs was 50-880 items/kg; among them, the most common MPs type being polypropylene (PP), mainly occurring as white/transparent fibers with small size (cross section <0.3 mm). SEM images of MPs surfaces revealed multiple features related to environmental exposure and degradation. ATR-FTIR spectroscopy and pyrolysis-GC/MS analyses enabled the accurate identification of MPs separated from the embedding soil micro- and macro-aggregates. Finally, contamination of the polymeric microparticles with a broad range of metals was found by ICP-MS analysis, suggesting that MPs can be vectors for transporting heavy metals in the soil and indicators of soil contamination as a result of mismanagement of industrial wastewaters.

Storage facilities reclamation using dredged sediments from waterways: Growing media formulation for plants according to the EU Ecolabel requirements.

Dredged sediments display a great potential for growing media applications; however, there are few studies about their beneficial reuse for the waste storage reclamation. This research study aims at checking the agronomic values and environmental impacts of three growing media based on waterways sediments (WSs) and green waste (GW) according ecolabel requirements. For this purpose, three growing media named GW0, GW25, and GW50 were prepared at field pilot scale by co-composting WS and GWs during 12 months. Samples were submitted to ecolabel analyses package. Following to the ecolabel requirements, the growing media comply with criteria like pH, electrical conductivity, trace elements and polycyclic aromatic hydrocarbon contents, chlorides, and pathogens, whereas they are not in compliance with the EU Ecolabel guidelines for propagules, organic matter, and zinc contents. Results of laboratory leaching tests performed according to NF EN 12457-2 for GW0, GW25, and GW50 have shown that sulfates, soluble fraction exceed limit for inert waste storage. Lysimeter tests at pilot scale were performed during 6 months to check the leaching potential of pollutants from growing media under real field conditions, including a European ecolabel product. Results demonstrate that Ba, Mo, Sb, Zn, Se, and Sb are higher in GW0, GW25, and GW50 than in the European ecolabel. As, Cd, Cr, Ni, and F- are more soluble in the commercial product compared to other growing media. This study allowed to demonstrate that main characteristics are fulfilling for reusing these growing media in the specific field of waste storage reclamation.

Microplastics on Barra beach sediments in Aveiro, Portugal.

Microplastic (MPs) pollution has been recognized as a serious threat to marine environment with the growing use of plastics. There is no sufficient data on the extent and characteristics of MPs pollution in the beach sediments and sand in the Atlantic Ocean. The coastal area is one of the main tourist zones in Aveiro in Portugal, thus, impacted by both tourism and maritime traffic, which are major sources of MPs. Considering this issue, 33 sediment samples were collected from the Praia da Barra beach in Aveiro. This pilot study showed that large quantities of MPs are accumulated on this beach with a median concentration of 100 MP kg-1 (15-320 MP kg-1), that is dominated by polyethylene (30%), polypropylene (27%), polystyrene (18%), nylon (12%), and polyester (6%). Size <1 mm constituted 99.5% of particles, mostly of transparent or black colors, with highest concentrations closest to the water line.

Indoor versus outdoor transmission of SARS-COV-2: environmental factors in virus spread and underestimated sources of risk.

The first case of Coronavirus Disease 2019 (COVID-19), which is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), in Europe was officially confirmed in February 2020. On 11 March 2020, after thousands of deaths from this disease had been reported worldwide, the WHO changed their classification of COVID-19 from a public health emergency of international concern to a pandemic. The SARS-CoV-2 virus has been shown to be much more resistant to environmental degradation than other coated viruses. Several studies have shown that environmental conditions can influence its viability and infectivity. This review summarizes current knowledge on the transmission pathways of the novel coronavirus, and directs attention towards potentially underestimated factors that affect its propagation, notably indoor spread and outdoor risk sources. The contributions of significant indoor factors such as ventilation systems to the spread of this virus need to be carefully ascertained. Outdoor risk sources such as aerosolized particles emitted during wastewater treatment and particulate matter (PM), both of which may act as virus carriers, should be examined as well. This study shows the influence of certain underestimated factors on the environmental behavior and survival of the SARS-CoV-2 virus. These aspects of coronavirus propagation need to be accounted for when devising actions to limit not only the current pandemic but also future outbreaks.

Types, occurrence, and distribution of microplastics and metals contamination in sediments from south west of Kerkennah archipelago, Tunisia.

Microplastics (MPs) are one of the most significant solid waste pollutants in the marine environment and accumulate in sediments around worldwide. In this study, the pollution level, the type, occurrence, and distribution of MPs in sediments from the southwestern Kerkennah archipelago, Tunisia, were investigated. Sediment samples were collected from 20 adjacent sites through three "lines L1, L2, and L3." MPs were separated from sediment by density flotation (NaCl, 1.2 g cm-3) and characterized in terms of shape, size, and color using microscope. The accumulation of toxic chemicals such as trace metals on microplastics was measured by atomic absorption microwave-assisted acid extraction. Polymer types were identified using FTIR-ATR spectroscopy. This study showed that microplastics were found in all samples, which emphasized that their extensive distribution throughout three lines by an average abundance of "MPs" was 611 items/m2. Among the shape categories of plastic particles, fiber and fragment were the most dominant frequent shapes (94%). The more frequent colors found were white (52.7%) and transparent (35.1%). Regarding the sizes, the microplastics below 1 mm were the most common accounting for 97% of all plastics. Results of trace metals Zn, Cu, Pb, Cr, and Ni in sediments with concentrations were reported as 3.48 µg/g, 0.41 µg/g, 0.38 µg/g, 0.33 µg/g, and 0.12 µg/g, respectively. Graphical abstract.

Potential of Eucalyptus globulus for the phytoremediation of metals in a Moroccan iron mine soil-a case study.

The contamination left by abandoned mines demands sustainable mitigation measures. Hence, the aim of this study was to examine the phytoremediator ability of Eucalyptus globulus Labill. to be used for cleaning up metal-contaminated soils from an African abandoned iron (Fe) mine (Ait Ammar, Oued Zem, Morocco). Plantlets of this species were exposed to a control (CTL), a reference (REF), and a mine-contaminated soil (CS). Morphological (growth, leaf area) and physiological stress biomarkers (photosynthetic efficiency, pigments content, leaf relative water, and malondialdehyde (MDA) levels) and metal bioaccumulation were assessed. The growth and leaf area of E. globulus increased overtime in all soils, although at a lower rate in the CS. Its photosynthetic efficiency was not markedly impaired, as well as MDA levels decreased throughout the experiment in CS. In this soil, higher metal contents were detected in E. globulus roots than in leaves, especially Fe (roots: 15.98-213.99 µg g-1; leaves: 5.97-15.98 µg g-1) and Zn (roots: 1.64-1.99 µg g-1; leaves: 0.67-1.19 µg g-1), indicating their reduced translocation. Additionally, though at low extent, the plants bioaccumulated some metals (Pb > Zn > Cu) from CS. Overall, E. globulus may be potentially used for the phytoremediation of metals in metal-contaminated soils.

Application of a standard risk assessment scheme to a North Africa contaminated site (Sfax, Tunisia) -Tier 1.

Phosphorus is a critical element to agriculture, consequently global phosphate rock demand will remain rising to feed a growing world population. The beneficiation of phosphorous ore gives rise to several tons of a waste by-product [phosphogypsum (PG)] which valorisation is limited, within other reasons, by the risks posed to environment and human health. Although threatening, the accumulation in stacks is the only procedure so far practiced by several countries as a means to get rid of this industrial externality. As part of a NATO Science for Peace Project (SfP 983311) this study describes the application of an environmental risk assessment (ERA) framework, to assess the risks posed by a PG stack to the surrounding soils, in Sfax, Republic of Tunisia. The ERA followed a weight of evidence approach, supported by two lines of evidence (LoE): the chemical (ChemLoE) and the ecotoxicological (EcotoxLoE). Integrated risks point for risk values greater than 0.5 in soils collected in PG stack surrounding area. Soil salinization, has likely contributed to the exacerbation of risks, as well as to the lack of consistency between both LoEs. This study highlights the need of rethinking the weight given to each LoE in ERA, in areas where soil salinization is a reality.

Health risk assessment of heavy metals exposure via consumption of crops grown in phosphogypsum-contaminated soils.

The management of phosphogypsum (PG) heap, located south of the Sfax city in Tunisia, has been going on for decades. But dumping this solid waste still poses environmental problems. Even though valorized as amendment to agriculture soils, the sanitary impact of this practice is not seriously considered. To assess the risk of the transference of contaminants from PG to agricultural soil-plants food chain, a wild plant species Salicornia arabica grown in PG-contaminated field and tomato (Lycopersicon esculentum) and oat (Avena sativa) grown in laboratory using different rates (10, 20 and 30%) of PG amendment, were tested. The cadmium, lead, chromium, nickel, copper and zinc concentrations in soils and plants were determined by atomic absorption spectrometry and by inductively coupled plasma-mass spectrometry, respectively. Measurements showed that Ni, Cu and Pb levels in the amended soils were below international standards except for Cd and Cr which exceeded Chinese, FAO/WHO and European allowable standard limits. Gathered results showed that the more the PG rate increases, the more the bioconcentration factors of heavy metals increased in plants, particularly in the roots. This is a prospective study assuming direct or indirect exposure scenario of different human cohorts by consuming varied common food stuffs. The Human Exposure to Soil Pollutants evaluation and United State Environment Protection Agency models were adopted for the hazard quotient calculation to assess the acceptability of sanitary risk related to each metal. The direct and indirect health risk assessments varied in the decreasing order: children, adolescents and then adults. Therefore, the PG amendment must not exceed the rate of 10%.

An eco-friendly epoxy polymer binder for the treatment of Tunisian harbor sediments: Laboratory investigations for beneficial reuse.

The management of dredged sediments poses serious environmental and economic problems because of their geochemical properties and in particular their pollutant content. In this research, marine sediments from Tunisian harbors were collected to study their beneficial reuse as construction materials using an eco-friendly polymer binder. Experimental investigations include the determination of physicochemical, mineralogical, and environmental parameters of sediments from the Sidi Mansour and Sidi Youssef areas in Tunisia. Prismatic mortar samples (4 × 4 × 16 cm) were prepared at laboratory scale using normalized sand and epoxy resin. Then their composition was modified by including a sediment fraction in the substitution of sand at rates ranging from 10 to 50% in dry mass. After a 7-day curing period, mortar samples were submitted to mechanical, physicochemical, and environmental analyses. Mortar samples including sediment fractions displayed lower strength than sand mortar used as control. This result is explained by the increase of porosity values in the mortar samples when sediment samples were incorporated. A positive relationship between porosity and compressive strength values was evidenced, suggesting that the compactness of granular skeleton could play an important role in the preparation of materials. From an environmental point of view, the mortar samples containing sediment fractions showed relatively low leaching levels, which confirms their suitability for the manufacturing of construction materials.

Comparison of Sample Preparation Methods for Multielements Analysis of Olive Oil by ICP-MS.

Elemental analysis of olive oils by Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is challenging because of the high organic load in olive oil samples and the low analyte concentrations. However, conflicting operating procedures in the preparation of oils prior to analysis by ICP-MS have been reported to overcome these difficulties. This study compared three methods of inorganic elements' extraction from olive oils: The two commonly used microwave-assisted, acid digestion, and liquid-liquid, ultrasound-assisted extraction methods; and an optimized method: The combined microwave digestion-evaporation. Overall, microwave digestion-based methods did not compare opportunely, and ultrasound-assisted extraction was found to provide the best accord between simplicity of use, detection limits and precision improvement. The detection limits were in the range of 0.3-160 µg·kg-1, 0.012-190 µg·kg-1 and 0.00061-1.5 µg·kg-1, while repeatabilities were in the range of 5-21%, 5.4-99% and 5.1-40% for the microwave digestion, the combined digestion-evaporation and the ultrasound assisted extraction, respectively. The ultrasound-assisted extraction is therefore recommended as a preparation method for olive oils prior to analysis by ICP-MS. The broader range of elements that can be accurately detected is expected to help increase the discriminatory power and performance of geographical traceability models.

Microplastic pollution in the sediments of Sidi Mansour Harbor in Southeast Tunisia.

Despite the increasing interest in microplastic (MP) research, the accurate prevalence, distribution and fate of these materials in the environment is yet poorly known and, consequently, a focus of debate. Hence, to better ascertain the presence of microplastics in specific environments, samples from 35 random sites distributed across a 4200-meter long section from the area of Sidi Mansour, Sfax-Tunisia, were collected and analyzed. MPs were extracted, digested with potassium hydroxide and dyed with Eosin B, for visual microscopy counting and sorting. Polymer composition and surface morphology were identified by FTIR-ATR spectroscopy and SEM microscopy. Total abundances ranged from 252 to-5332 particles per m2 where fragments and granules were the most frequent types of microplastics. These findings highlight the considerable presence of these materials in the studied harbor region and underscore the density dependence on the distribution and occurrence of MPs and how these tend to accumulate in the sandy sediments.

Interregional traceability of Tunisian olive oils to the provenance soil by multielemental fingerprinting and chemometrics.

The aim of this study was to prove the usefulness of multielements as provenance markers of olive oils by evaluating their link with soil composition and their discriminatory power. Eleven elements in twenty-one olive oils and their paired soils from four Tunisian regions were characterized. Chemometrics have been implemented for ICP-MS data processing. Principal component analysis identified the predominant geochemical source of the elements in the oils based on their associations according to Goldschmidt's rule. Although a clear correlation was not proven, correspondence was identified between the discriminating elements for both the soils and olive oils, which included Fe, Rb, Mg, and Pb. Linear discriminant analysis achieved classification and prediction rates of 92.1% and 87.3%, respectively. Our study substantiates the validity of multielements as markers of the olive oils' provenance, and that an elemental fingerprinting approach can be successfully applied in the construction of a database of Tunisian olive oils.

Decision tree for mapping of halophyte cover around Ghannouch, Tunisia.

Environment of Ghannouch in the south-east of Tunisia is characterized by the wide-spread hypersaline soils, typically colonized by halophytes. The study of their distribution is required in order to reveal the extent of salinization and its dynamic. Mapping and monitoring with a remote sensing approach are foreseen as the ways to trace the spatial and temporal dimensions of the phenomenon. The identification of halophyte vegetation can take advantage by analyzing optical remote sensing data. Here, we propose using a decision tree approach applied to European Space Agency Sentinel-2 imagery, for an accurate land cover mapping of Ghannouch district in Gabès governorate. Data pre-processing was carried out using the European Space Agency's Sentinel Application Platform and the SEN2COR toolboxes. The mapping approach combines the spectral information in several channels of the visible-near-infrared spectrum. The land cover identification was performed following a spectral classification approach, exploiting several optical indices, normalized difference water index, normalized difference vegetation index, and several soil salinity index, in order to elaborate a decision tree algorithm. As a result, for an area of interest of 50 × 50 km2, at least 68% was classified as halophyte land cover. This mapping exercise represents an important step toward improved halophytes mapping in Tunisia and could be used to monitor the status of other salinity prone regions in the world.