[Progress in research of long-term protective efficacy of human papillomavirus vaccine].

The efficacy of HPV vaccine in preventing cervical cancer has been demonstrated in numerous clinical trials and clinical uses. The follow-up after clinical trials usually last for 5-6 years to evaluate the long-term efficacy, and a series of long-term follow-up studies have been conducted in some regions. The literature retrieval of HPV vaccine long term efficiency research both at home and abroad indicated that the protective efficacy of the vaccine against vaccine-type-related cervical intraepithelial neoplasia grade 2 and above is higher than 90%.

[Epidemiological survey of childhood leukemia].

This paper reports epidemiological data of childhood leukemia in the 14 years 1973-1986 in Qidong county, Jiangsu province. Mortality of childhood leukemia was 1.74 per 10 million, taking first place among various malignant tumors of children. The annual mortality distribution of this disease and the age and season at death showed no significant difference, But finer age grouping of death rates revealed remarkable difference. Thus, in 0-4 age-group the mortality was 2.95 per 10 million higher than the remainder. Childhood leukemia mortality by space-Time Clusters analysis showed the significance of difference lobe P greater than 0.05, suggesting that childhood leukemia mortality in space and time clusters were random.