RESUMO
To determine urine cholinesterase activity in full-term neonatal infants with varying ischemic nephropathy in an intensive care unit, the investigators studied this enzyme on days 1 and 5-7 of life, by using a kinetic photometric test optimized according to the Deutsche Gesellschaft fur Klinische Chemie (German Society for Clinical Chemistry) recommendations. In the early neonatal period, the newborns with grade III ischemic nephropathy were found to have a high urine cholinesterase activity. The determination of urine cholinesterase activity just on the first day of life may be used for the early diagnosis of grade III ischemic nephropathy in the newborns until the clinical manifestations of this pathology develop.
Assuntos
Colinesterases/urina , Doenças do Recém-Nascido , Isquemia , Nefropatias , Rim/irrigação sanguínea , Feminino , Humanos , Recém-Nascido , Doenças do Recém-Nascido/diagnóstico , Doenças do Recém-Nascido/enzimologia , Doenças do Recém-Nascido/urina , Isquemia/diagnóstico , Isquemia/enzimologia , Isquemia/urina , Nefropatias/diagnóstico , Nefropatias/enzimologia , Nefropatias/urina , MasculinoRESUMO
The dynamics and role of inherent malformations in the structure of infant mortality in Ivanovskaya oblast from 2007 to 2008 is analyzed. The data on the rate of inherent handicaps in population is received. The decrease of mortality among children younger than 1 year is revealed. The higher percentage of inherent malformations in the structure of infant mortality due to inherent valvular heart disease, nervous system, kidney diseases and multiple inherent malformations in male newborns are identified.
Assuntos
Anormalidades Congênitas/mortalidade , Mortalidade Infantil/tendências , População Rural , Causas de Morte/tendências , Feminino , Humanos , Recém-Nascido , Masculino , Estudos Retrospectivos , Federação Russa/epidemiologia , Taxa de Sobrevida/tendênciasRESUMO
To ascertain the level of medium-weight molecules in the plasma and urine in critically ill neonatal infants with varying ischemic nephropathy, the authors determined the content of medium-weight molecules by N. I. Gabrielyan's procedure modified by M. Ya. Malakhova. Within the first 24 hours of life, the newborn infants with ischemic nephropathy had high plasma levels of medium-weight proteins. The high plasma levels of medium-weight molecules were attended by their urinary elimination in first- and second-grade ischemic nephropathy and these were not compensated for by their elimination in third-grade nephropathy, which was linked to decreased renal excretory function. The determination of medium-weight molecules in the plasma and urine permits identification of acute renal failure in the newborn.
