1.
Nat Prod Res
; 25(2): 169-74, 2011 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21246444
RESUMO
Three aromatic sesquiterpene derivatives, (+)-(7R, 10S)-2-methoxy calamenene (1), (+)-(7R, 10S)-2,5-dimethoxy calamenene (2) and (+)-(7R, 10S)-2-methoxy-5-acetoxy calamenene (3) were isolated from the methanol extract of the Indian gorgonian Subergorgia reticulata. Compound 2 has not been previously described in the literature. Compound 3 has not been isolated previously from a natural source. Compounds 1, 2 and 3 showed settlement inhibition activity against cyprids of Balanus amphitrite with EC(50) values of 4.4, 7.8 and 0.03 µg mL(-1), respectively. These compounds also exhibited considerable activity against Artemia nauplii at 50 µg mL(-1), indicative of their potential use as cytotoxic agents.