[The dynamics of histograms of difference between successive RR intervals of ECG during 24 hours as index of the balanced state of neurogenic influences on the heart rate].

The quantitative parameters of neurogenic influences on the heart rate is offered: the dispersion of histograms of differences between successive RR intervals of ECG, the number of zero differences and the value of sum of differences between successive RR intervals.

[The quantitative analysis of the balanced state (or condition) of the neurogenic influences on the heart rhythm].

The technique of the analysis of the R-R subsequent series intervals differences in the prolonged heart rhythm records is offered. The differences reflect the certain regularities of the heart rhythm change (heart rate deceleration and heart rate acceleration). The offered parameters of the differences characterize the condition of the heart and the whole organism.

[Special characteristics of electrocardiogram in healthy children and adolescents].

Special characteristics of electrocardiogram of healthy children in the process of their growth and development are presented as well as specific changes which can be seen in practically healthy children. There are differences between electrocardiograms of children and adults. Moreover some specific peculiarities which emerge during each age period can cause difficulties in analysis and interpretation of obtained data.

[Zinc and copper blood plasma and erythrocyte value in adolescent with the different types of pathology].

Comparative analysis the value of the cation of zinc and copper in the blood plasma and erythrocytes were performed in the different diseases in children and adolescent. The patients with bronchopulmonary diseases, liver diseases, low cardiovascular malformation and growth inhibition were examined. Increase the value of the intracellular zinc and copper was detected in patients with the definite bronchopulmonary diseases, which can on the one hand, reflected the activation of the antioxidant protection system and by another hand, reflected destructive metalloproteinase. Decrease the value of the intracellular copper in bronchopulmonary patients with the lung emphysema and Kartagnera syndrome indicate about the falure of the compensatory reactions and needs the additional investigation. It was detected that copper content in the blood plasma and the copper accumulation in erythrocyte were decrease in patients with liver diseases in comparison with the health children. The increase of copper value in erythrocyte in children with low cardiovascular malformation was detected and need the additional investigation. In children with the growth inhibition was detected appreciable decrease the value of the free zinc and copper ions in erythrocytes and copper in the blood plasma, which can explained the physical developmental lagging.

[Clinical value of the use of magnesium orotate in adolescents with syndrome of cardiac connective tissue dysplasia].

According to results of clinical and instrumental investigation magnesium orotate (50 mg/day during first week and 25 mg/day thereafter) was found to be effective therapy of children with syndrome of cardiac connective tissue dysplasia (mainly with mitral valve prolapse and anomalous chordae tendineae).

[The effect of a low-frequency magnetic field on erythrocyte membrane function and on the prostanoid level in the blood plasma of children with parasystolic arrhythmia]. / Vliianie nizkochastotnogo magnitnogo polia na sostoianie membran éritrotsitov i soderzhanie prostanoidov v plazme krovi detei s parasistolicheskoi aritmiei.

As shown by clinical and biochemical evidence on 23 parasystolic children, the treatment with low-frequency magnetic field improves humoral and cellular processes participating in cardiac rhythm regulation. There is activation of Ca, Mg-ATPase in the red cells, a reduction of plasma thromboxane levels. Red cell phospholipid composition insignificantly change. Further courses of magnetotherapy may lower the risk of recurrent arrhythmia.

[ECG changes in hypertrophic cardiomyopathy in children (data of routine and circadian ECG)]. / Izmeneniia EKG pri gipertroficheskoi kardiomiopatii u detei (po dannym obychnoi i sutochnoi EKG).

Analysis is made of the routine and circadian ECG in 32 children with hypertrophic cardiomyopathy. The signs of myocardial hypertrophy of some or other parts of the heart were discovered in 29 children (90.6%). The signs of left ventricular hypertrophy were the most suggestive ones, whereas the signs of left atrial hypertrophy and right heart hypertrophy were observed less frequently. The use of the daily ECG monitoring allowed rhythm and conduction disorders to be revealed in 30 children (93.8%). It should be mentioned that in patients with the obstructive form of the disease, the signs of myocardial hypertrophy and heart arrhythmia on the ECG occurred much more often than in children suffering from the non-obstructive form. In accordance with the observations, prognostically unfavourable disorders of heart rhythm are not characteristic of children, they occur rarely, being primarily seen in the obstructive form of the disease. The daily ECG monitoring not infrequently allows the identification of heart arrhythmias and transitory disorders of conduction, which cannot be recorded on routine electrocardiography.

[Arrhythmia in children with dilated cardiomyopathy (data of 24-hour ECG monitoring)]. / Narusheniia ritma serdtsa u detei s dilatatsionnoi kardiomiopatiei (po dannym sutochnogo monitorovaniia EKG).

The authors demonstrate potentialities of long-term ECG monitoring in the diagnosis of heart rhythm and conduction disturbances in children with dilated cardiomyopathy. Provide the results of comparative studies of routine and 24-hour ECG monitoring in children with dilated cardiomyopathy under every-day life conditions. Show that during 24-hour ECG monitoring, all the children with the above pathology manifest heart rhythm and conduction disturbances of varying intensity and prognostic significance.

[Additional phonocardiographic symptom and the functional state of the heart during mitral valve prolapse in children]. / O dopolnitel'nom fonokardiograficheskom simptome i funktsional'nom sostoianii serdtsa pri prolapse mitral'nogo klapana u detei.

A review of the clinical pattern and heart function in 50 children (aged 6 to 15 years) with mitral valve prolapse (MVP) demonstrated that MVP was mild or of medium severity and had a favourable course in most of the cases. Systolic extratone due to MVP can be manifested to the greatest degree within the low-frequency range of phonocardiograms. Morphometric and functional electrocardiographic parameters were within the normal range in most of the children. The transitory nature of MVP in some of the cases suggests a functional origin of the disease, with vegetovascular dystonia, temporary dysfunction of papillary muscles or reversible myocardial dystrophy as provoking factors.