[Dynamics of hantavirus detection in the excretory organs of Apodemus mice and its relation to epidemic manifestations of hantavirus infection].

This paper presents data on the detection of hantavirus in the excretory organs of Apodemus mice which are natural carriers of pathogenic hantaviral serotypes in the Primorye Region. Acute infection periods were detected in naturally infected rodents with the highest hantavirus dissemination to the environment in different phases of rodent population cycles. There was a relationship between the rise of morbidity and the seasonal manifestation of hemorrhagic fever with renal syndrome morbidity and activity of hantavirus reproduction in the murine excretory organs.

[The ecological aspects of the epidemiology of hemorrhagic fever with renal syndrome in the south of the Far East in Russia]. / Ekologicheskie aspekty épidemiologii gemorragicheskoi likhoradki s pochechnym sindromom na iuge Dal'nego Vostoka Rossii.

The data on the relationship between the epizootic process in the population of mice (the source of Hantavirus infection) and the seasonal manifestations of morbidity in hemorrhagic fever with renal syndrome (HFRS) in the southern region of the Russian Far East are presented. The asynchronous course of the epizootic process in the population of rodents causes irregularity in the spread of HFRS in the region and periodicity in the appearance of foci. Seasonal rises in HFRS morbidity coincide with the activity of the epizootic process in the population of mice: spring-summer rises with an increase in the number of infected rodents in the populations of large Japanese field mice and autumn-winter rises in voles.

[The role of Hantaan virus serotypes in the etiology of hemorrhagic fever with renal syndrome in the Far East of the USSR]. / Izuchenie roli serotipov khantavirusa v étiologii gemorragicheskoi likhoradki s pochechnym sindromom na Dal'nem Vostoke SSSR.

The employment of two serological tests (indirect fluorescence antibody technique and neutralization test) demonstrated the leading role of Hantaan virus serotype 1 strains isolated from field mice in the pattern of the incidence of hemorrhagic fever with renal syndrome (HFRS). Proofs of the etiological importance of strains of serotypes 3 and 5 occurring in brown rats and Cl. rufocanus were obtained. No data on any association of human HFRS cases with strains of serotype 4 isolated from reed voles could be demonstrated.