[Aerospace toxicology: basic stages of formation and prospects of development]. / Aviatsionno-kosmicheskaia toksikologiia, osnovnye étapy stanovleniia i perspektivy razvitiia.

The review shows the basic stages of development of aerospace toxicology. It traces the way of forming this research direction from its origin to the present day. Study methods are being improved as practical tasks are becoming more intricate. The names of the Institute's employees who take an active part in the development of this problem and the advances made are enlisted. The results of researches are summed up and further trends are outlined.

[Adaptation to anthropogenic chemical compounds in human applied ecology]. / Nekotorye aspekty adaptatsii k antropogennym khimicheskim soedineniiam v prikladnoi ékologii cheloveka.

The literature data pointing to the fact that man can actively adapt to the effect of chemical substances at doses not exceeding hygienic norms are presented. However using some medical measures it is possible to increase to some extent the body resistance to the effect of chemical impurities of the environment and thus delaying for some time the development of disadaptation disorders induced by these impurities.

[Use of bemitil for increasing the resistance of the human body to combined effects of carbon monoxide and heating microclimate]. / Ispol'zovanie bemitila dlia povysheniia ustoichivosti organizma cheloveka k sochetannomu vozdeistviiu oksida ugleroda i nagreva- iushchego mikroklimata

Basing on experimental data, it was established that single administration of 0.5 mg bemitil increased human resistance to carbon oxide in concentration 300 mg/m3. The use of bemitil optimized human body state in the conditions of the complex influence of carbon oxide and extreme heating microclimate.

[Various characteristics of the action of chemical substances on general adaptability of the body]. / O nekotorykh osobennostiakh vliianiia khimicheskikh soedinenii na obshchuiu adaptosposobnost' organizma.

The article presents a summation of medical literature data and the author's personal studies to the effect that human organism's real adaptation to chemical compounds' action can exist only within standardized limits. Deadapting and disadapting chemical actions have been studied, and it was shown that the peculiarities of their action on the organism's adaptability determine the nature of the total biological response in case with complex chemical and other actions.

[Quantitative evaluation of combined effects of carbon monoxide, toluene and hot microclimate on humans]. / Kolichestvennaia otsenka sochetannogo deistviia na organizm cheloveka oksida ugleroda, toluola i nagrevaiushchego mikroklimata.

As a result of the proposed study it was established that a complex action of carbon oxide and toluene++ in 300 mg/m3 concentration in a combination with heating microclimate (leading to a maximum heat labour condition) results in an increased total biological effect. The coefficient to the complex action of carbon oxide and heating microclimate is equal to 2.5 and toluene++ and heating microclimate to 1.9. These coefficients should be taken into account in establishing hygienic norms for the chemical compounds.

[The questions of the combined action on the body of industrial chemical compounds and ionizing radiations]. / Nekotorye voprosy sochetannogo deistviia na organizm promyshlennykh khimicheskikh soedinenii s ioniziruiushchimi izlucheniiami.

Proceeding from the analysis of literature data on the problem of the combined body effect of chemical industrial compounds, a methodological approach to the problem has been developed in order to regulate hygienically the concentration of industrial poisons in the work zone air under the combined effect of ionizing radiation and industrial chemical compounds.

[Short-term action of high carbon monoxide concentrations on the psychophysiological functions of a human operator]. / Issledovanie kratkovremennogo vozdeistviia vysokikh kontsentratsii okisi ugleroda na nekotorye psikhofiziologicheskie funktsii cheloveka-operatora.

Experiments on volunteers, aged 26-40, demonstrated that a 10-minute exposure to carbon monoxide at a concentration of 900 +/- 20 mg/m3 caused a significant decline of the quality of their operator's function. The task they performed was a two-dimensional compensatory tracking task combined with mental arithmetic. Some of the test subjects showed symptoms of mild CO intoxication which preceded disorders in their work and were accompanied by an increase of HbCO to 10 +/- 0.57%. Such an exposure to CO should be regarded as hazardous since it may increase the probability of erroneous actions particularly, of the flying personnel.