Electrical and Optical Properties of Silicon OxideLignin Polylactide (SiO2-L-PLA).

This paper presents a study on the electrical properties of new polylactide-basednanocomposites with the addition of silicon-dioxide-lignin nanoparticles and glycerine as a plasticizer.Four samples were prepared with nanoparticle mass fractions ranging between 0.01 to 0.15(0.01, 0.05, 0.10, and 0.15), and three samples were prepared without nanoparticle filler-unfilledand unprocessed polylactide, unfilled and processed polylactide, and polylactide with Fusabondand glycerine. All samples were manufactured using the melt mixing extrusion techniqueand injection molding. Only the unfilled and unprocessed PLA sample was directly preparedby injection molding. Dielectric properties were studied with broadband spectroscopy in a frequencyrange from 0.1 Hz to 1 MHz in 55 steps designed on a logarithmic scale and a temperature rangefrom 293.15 to 333.15 K with a 5 K step. Optical properties of nanocomposites were measuredwith UV-VIS spectroscopy at wavelengths from 190 to 1100 nm. The experimental data show thatthe addition of silicon-dioxide-lignin and glycerine significantly affected the electrical propertiesof the studied nanocomposites based on polylactide. Permittivity and electrical conductivity showa significant increase with an increasing concentration of nanoparticle filler. The optical properties arealso affected by nanofiller and cause an increase in absorbance as the number of silicon-dioxide-ligninnanoparticles increase.

Captopril apparently increase and cisplatin apparently decrease human albumin concentration in artificial urinary solutions.

BACKGROUND: Measurement of urinary albumin (HSA) is very important in diagnostic of kidney diseases. Much less is known about the possible impact of substances present in urine together with albumin on the results of measurements. METHODS: We investigated the effect of the presence of captopril and cisplatin in the solution on the result of the determination of HSA by native polyacrylamide gel electrophoresis. Protein conformation in the absence and presence of the drugs was examined using Fourier Transform Infrared Spectroscopy (FTIR). RESULTS: The presence of captopril apparently increases HSA concentration while cisplatin causes an apparent decrease in the HSA concentration. The presence of both drugs also influence the secondary structure forms of HSA albumin investigated by FTIR. CONCLUSION: Both drugs tested in the concentration of human use can have an impact on the results of determination of albumin in urine which can influence clinical decision.