1.
Clin Endocrinol (Oxf)
; 80(5): 770-1, 2014 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23803013
Assuntos
Predisposição Genética para Doença , Variação Genética , Paralisia Periódica Hipopotassêmica/diagnóstico , Canais de Potássio Corretores do Fluxo de Internalização/genética , Adulto , Estudos de Casos e Controles , China , Frequência do Gene , Genótipo , Doença de Graves/genética , Humanos , Masculino , Pessoa de Meia-Idade , Análise de Sequência de DNA , Temperatura , Tailândia
2.
Zhonghua Wai Ke Za Zhi
; 45(18): 1264-6, 2007 Sep 15.
Artigo
em Chinês
| MEDLINE
| ID: mdl-18067741
RESUMO
OBJECTIVE: To investigate whether the MTNR1A gene promotor polymorphism (rs2119882) are associated with the occurrence or curve severity of adolescent idiopathic scoliosis (AIS). METHODS: 226 AIS patients and 277 normal controls were recruited. The maximum Cobb angles were recorded in AIS patients. PCR-RFLP was used for the genotyping. RESULTS: The genotype and allele frequency distribution were comparable between AIS and normal control, the mean maximum Cobb angle of different genotypes of rs2119882 were similar with each other among AIS patients. CONCLUSION: The MTNR1A gene promoter polymorphism was neither associated with the occurrence nor the curve severity of AIS.