2-years retrospective observational case-control study on survival and marginal bone loss of implants in patients with hereditary coagulopathies

Background: Evaluating 2-years implant loss and marginal bone loss in patients with hereditary coagulopathies, comparing with a healthy control group. Material and Methods: 37 implants in 13 patients (17 haemophilia A, 20 Von-Willebrand disease) versus 26 implants in 13 healthy patients. Data measured through Lagervall-Jansson index (after surgery, at prosthetic loading, at 2 years). Statistics: Chi-square, Haberman’s, ANOVA, Mann-Whitney-U. Significance p<0.05. Results: Haemorrhagic accidents in 2 coagulopathies patients (non-statistical differences). Hereditary coagulopathies patients suffered more hepatitis (p<0.05), HIV (p<0.05) and less previous periodontitis (p<0.01). Non-statistical differences in marginal bone loss among groups. 2 implants were lost in the hereditary coagulopathies and none in the control group (non-statistical differences). Hereditary coagulopathies patients had longer (p<0.001), and narrower implants (p<0.05) placed. 43.2% external prosthetic connection in hereditary coagulopathies patients (p<0.001); change of prosthetic platform more frequent in control group (p<0.05). 2 implants lost: external connection (p<0.05). Survival rate 96.8% (hereditary coagulopathies 94.6%, control group 100%). Conclusions: Implant and marginal bone loss at 2 years is similar in patients with hereditary coagulopathies and control group. Precautions should be taken on the treatment for hereditary coagulopathies patients, through prior haematological protocol. Implant loss only occurred in in a patient with Von-Willebrand´s disease. (AU)

Four years survival and marginal bone loss of implants in patients with Down syndrome and cerebral palsy.

OBJECTIVES: To evaluate implant survival rate and marginal bone loss (MBL) after 4 years in patients with Down syndrome and cerebral palsy, compared with a healthy control group. MATERIAL AND METHODS: The case group comprises 102 implants in 19 patients (71 cerebral palsy, 21 Down syndrome), and the control group comprises 70 implants in 22 healthy patients. One implant per patient was selected (n = 41 implants) to take clustering effects into account. MBL was measured using two panoramic radiographs (after surgery and 4 years later). Lagervall-Jansson's Index was used. Statistics used are chi-squared test and Haberman's post hoc test. p Value is significant at <0.05. RESULTS: MBL was significantly higher in the cases in all samples (p < 0.001) and when one implant was selected per patient (p < 0.05). More implants were lost in the cases (p < 0.01), especially those with a higher MBL (p < 0.01). MBL (p < 0.05) and implant loss (p < 0.01) increased with age in the cases. The three-unit fixed dental prosthesis (FDP) showed higher MBL (p < 0.05). Down syndrome had a higher MBL than cerebral palsy (entire sample p < 0.0001, one implant per patient p < 0.05). All patients with Down syndrome saw some damage to bone support (entire sample p < 0.0001; one implant per patient p < 0.05). Implant loss occurred only in Down syndrome (p < 0.00001). CONCLUSIONS: MBL and implant loss 4 years after placement are higher in neuropsychiatric disabilities. Down syndrome has a higher risk of MBL and implant loss; therefore, special precautions should be taken when deciding on treatment for these patients. CLINICAL RELEVANCE: As a consequence of this pilot study, professionals should be very cautious in placing implants in patients with Down syndrome.

Current methods of sedation in dental patients - a systematic review of the literature

OBJECTIVE: The main objective of this systematic literature review is to identify the safest and most effective sedative drugs so as to ensure successful sedation with as few complications as possible. Study DESIGN: A systematic literature review of the PubMed MEDLINE database was carried out using the key words "conscious sedation", "drugs", and "dentistry". A total of 1,827 scientific articles were found, and these were narrowed down to 473 articles after applying inclusion and exclusion criteria. These 473 studies were then individually assessed for their suitability for inclusion in this literature review. RESULTS: A total of 21 studies were selected due to their rigorous study design and conduciveness to further, more exhaustive analysis. The selected studies included a total of 1,0003 patients classified as ASA I or II. Midazolam was the drug most frequently used for successful sedation in dental surgical procedures. Ketamine also proved very useful when administered intranasally, although some side effects were observed when delivered via other routes of administration. Both propofol and nitrous oxide (N2 O) are also effective sedative drugs. CONCLUSIONS: Midazolam is the drug most commonly used to induce moderate sedation in dental surgical procedures, and it is also very safe. Other sedative drugs like ketamine, dexmedetomidine and propofol have also been proven safe and effective; however, further comparative clinical studies are needed to better demonstrate which of these are the safest and most effective

Survival of dental implants in patients with Down syndrome: A case series.

STATEMENT OF PROBLEM: The need for tooth replacement in individuals with Down syndrome (DS) is explained by the high prevalence of dental agenesis and by the premature loss of teeth through severe periodontal disease. Dental implants may be the dental procedure of choice in some of these patients. PURPOSE: The purpose of this clinical study was to analyze dental implant survival in a series of patients with DS. MATERIAL AND METHODS: This was a multicenter, retrospective, observational study. Information on patients was gathered using a standardized questionnaire designed specifically for this study, including personal details, oral health status, information on the surgical and prosthetic phases, and follow-up visits. The questionnaire was sent to centers registered with the research network of the Spanish Society of Special Needs Dentistry (SEOENE). Patients with DS aged 18 years or older were included in the study if they had at least 1 dental implant and the corresponding prosthesis and had been followed up for at least a year. RESULTS: The study population was formed of 25 adult patients (13 men and 12 women) aged between 19 and 60 years. The interventions were performed by 5 different dental surgeons, usually under general anesthesia or deep sedation (n=17 patients). A total of 73 implants were inserted, 30 in the maxilla and 43 in the mandible, most commonly in the anterior region (n=51). The mean time to loading the implants was 4.1 ±1.3 months after surgery (range, 1 to 7 months). All patients completed prosthetic rehabilitation; the most frequent design used was the single fixed prosthesis (n=13 patients). A total of 17 (23.2%) implants failed in 8 (32%) patients; the majority (n=14 implants) failed in the postsurgical period before implant loading. The distribution by patients was 1 implant failure in 6 patients, 3 failures in 1 patient, and 8 failures in 1 patient. CONCLUSIONS: Dental implant survival is lower in individuals with DS than in the general population. The reasons for early implant failure in these patients have still not been clearly identified.

Correlation between permanent tooth eruption pattern and the predominance of the motor function laterality

OBJECTIVES: To asses whether dental eruption order can play a role in the early diagnosis of crossed laterality. STUDY DESIGN: Dental eruption pattern along with eye, ear, hand and foot lateralism were examined on 131 children between 6 to 8 years old from public schools from a multietnic population area of Barcelona city. Statistic methods (Statgraphics Plus 5.1 program) were used to evaluate data recollected. RESULTS: Only foot and dentition lateralities behave as independent variables regarding hand laterality. So dental eruption laterality (along with the foot one) would be one of the parameters more related to hand laterality given that dentition variable relationship is greater that the foot one. This suggests that tooth eruption could be more clinically relevant. Crossed laterality hand-foot is significantly more predominant in men (13%) than in women (1,6%). Meanwhile, the relationship between hand and dentition didn't show any influence of sex. CONCLUSIONS: Dental eruption order, can be used as a good parameter in the determination of the patient's laterality

Implants in disabled patients: A review and update

The range of indications for dental implants has broadened enormously owing to their predictability and the improvement of patient satisfaction in terms of stability, comfort, aesthetics and functionality. The aim of this article is to review those indications in patients with mental or physical disabilities as the difficulty to cope with oral hygiene often leads to teeth extraction, adding edentulousness to the impairments already present. Following that goal, available literature in Pubmed database, Scopus, Web of Knowledge and The Cochrane Library database about dental implants placement in these patients has been reviewed, assessing the variables of each study: number of patients, sex, average age, oral hygiene, parafunctional habits, impairment, bone quality, protocol of implant surgery, necessity of deep intravenous sedation or general anesthesia, follow-up period and number of failures. The comparison with studies involving other patient populations without mental or physical impediments did not show statistically significant differences in terms of the failure rate recorded. Although there is not much literature available, the results of this review seem to suggest that osseointegrated oral implants could be a therapeutic option in patients who suffer from any physical or psychological impairment. The success of an oral rehabilitation depends mainly on an adequate selection of the patients

Correlation between permanent tooth eruption pattern and the predominance of the motor function laterality.

OBJECTIVES: To asses whether dental eruption order can play a role in the early diagnosis of crossed laterality. STUDY DESIGN: Dental eruption pattern along with eye, ear, hand and foot lateralism were examined on 131 children between 6 to 8 years old from public schools from a multietnic population area of Barcelona city. Statistic methods (Statgraphics Plus 5.1 program) were used to evaluate data recollected. RESULTS: Only foot and dentition lateralities behave as independent variables regarding hand laterality. So dental eruption laterality (along with the foot one) would be one of the parameters more related to hand laterality given that dentition variable relationship is greater that the foot one. This suggests that tooth eruption could be more clinically relevant. Crossed laterality hand-foot is significantly more predominant in men (13%) than in women (1,6%). Meanwhile, the relationship between hand and dentition didn't show any influence of sex. CONCLUSIONS: Dental eruption order, can be used as a good parameter in the determination of the patient's laterality.

Implants in disabled patients: a review and update.

The range of indications for dental implants has broadened enormously owing to their predictability and the improvement of patient satisfaction in terms of stability, comfort, aesthetics and functionality. The aim of this article is to review those indications in patients with mental or physical disabilities as the difficulty to cope with oral hygiene often leads to teeth extraction, adding edentulousness to the impairments already present. Following that goal, available literature in Pubmed database, Scopus, Web of Knowledge and The Cochrane Library database about dental implants placement in these patients has been reviewed, assessing the variables of each study: number of patients, sex, average age, oral hygiene, parafunctional habits, impairment, bone quality, protocol of implant surgery, necessity of deep intravenous sedation or general anesthesia, follow-up period and number of failures. The comparison with studies involving other patient populations without mental or physical impediments did not show statistically significant differences in terms of the failure rate recorded. Although there is not much literature available, the results of this review seem to suggest that osseointegrated oral implants could be a therapeutic option in patients who suffer from any physical or psychological impairment. The success of an oral rehabilitation depends mainly on an adequate selection of the patients.

Cornelia de Lange syndrome: a case report.

Cornelia de Lange is a genetic syndrome which affects between 1/10.000 and 1/60.000 neonates, but its genetic bases are still not clear. Its principal clinical characteristics are the delay in growth and development, hirsute, structural anomalies in the limbs and distinctive facial characteristic. Dental problems are frequent and include: ogival palate, micrognathia, dental malalignment, delayed teething, microdontic teeth, periodontal disease and dental erosion produced by gastric reflux. Discussed is the case of a 29 year old patient affected by the syndrome in question, which presents the principal clinical characteristics. The patient's general state of health is acceptable, without cardiac or respiratory alterations. The intraoral exploration shows policaries, periodontal disease, persistence of the temporal teeth and ectopic molars. After completing the necessary pre-operatory preparations, the entire odontological treatment was carried out under general aesthesia, due to the patient's total lack of collaboration.

Cornelia de Lange syndrome: A case report

Cornelia de Lange is a genetic syndrome which affects between 1/10.000 and 1/60.000 neonates, but its genetic bases are still not clear. Its principal clinical characteristics are the delay in growth and development, hirsute, structural anomalies in the limbs and distinctive facial characteristic. Dental problems are frequent and include: ogival palate, micrognathia, dental malalignment, delayed teething, microdontic teeth, periodontal disease and dental erosion produced by gastric reflux. Discussed is the case of a 29 year old patient affected by the syndrome in question, which presents the principal clinical characteristics. The patient’s general state of health is acceptable, without cardiac or respiratory alterations. The intraoral exploration shows policaries, periodontal disease, persistence of the temporal teeth and ectopic molars. After completing the necessary pre-operatory preparations, the entire odontological treatment was carried out under general aesthesia, due to the patient’s total lack of collaboration

El síndrome de Cornelia de Lange es un síndrome genético que afecta entre 1/10.000 y 1/60.000 neonatos, y cuyas bases genéticas todavía no están claras. Sus características clínicas principales son el retraso en el crecimiento y en el desarrollo, hirsutismo, anomalías estructurales en miembros y unas características faciales distintivas. Los problemas dentales son frecuentes e incluyen: Paladar ojival, micrognátia, malposición dental, retraso en la erupción, microdoncia, enfermedad periodontal y erosión dental producida por el reflujo gástrico. Se describe el caso de una paciente de 29 años de edad afecta por el síndrome en cuestión, que presenta las principales características clínicas. El estado general de la paciente es aceptable, sin alteraciones cardíacas ni respiratorias. La exploración intraoral muestra policaries, enfermedad peridontal,pesistencia de dientes temporales y cordales ectópicos. Después de realizar las pruebas preoperatorios necesarias, se realiza el tratamiento odontológico completo bajo anestesia general, debido a la nula colaboración de la paciente

Consideraciones y diferencias en el tratamiento de un diente fusionado / Considerations and differences in the treatment of a fused tooth

Las malformaciones dentales referentes a bigeminismos, fusiones dentarias, etc. presentan una prevalencia que oscila de 0,5 a 5%, dependiendo de factores geográficos, raciales o genéticos. Ello puede comportar una modificación en el tratamiento a llevar a cabo en cada caso particular. La presencia de anomalias en la forma, tamaño y número de dientes es mayor en los llamados síndromes genéticos pediátricos, en muchos de los cuales el retraso mental es una característica asociada. El objetivo de este trabajo es analizar dos casos clínicos similares de fusión dentaria en un incisivo central y trazar un plan de tratamiento individualizado, diferente según las características de cada paciente. El primer caso clínico se trata de un niño de 9 años sano, que presentaba un incisivo central superior fusionado a un supernumerario. El diente fusionado presentaba dos raices independientes y convergentes con una única cámara pulpar, que fue tratado mediante endodoncia, odontosección y reconstrucción con composite de la corona, reservándose para un segundo tiempo el tratamiento ortodóncico. El segundo caso clínico se trata de un paciente de 27 años con una disminución psíquica severa, epiléptico, afecto de hiperplasia gingival con ausencia total de higiene oral. El tratamiento consistió únicamente en la resolución del problema periodontal mediante cirugía e instauración de un programa exhaustivo de prevención con normas de higiene oral, implicando a padres y personal asistencial. Como conclusión diremos que en la elaboración del plan de tratamiento odontológico a llevar a cabo en dos casos de fusión dentaria influye como factor determinante el grado de colaboración asociado a la disminución psíquica severa en uno de ellos, con lo que resulta un tratamiento completamente diferente en cada caso (AU)

Dental malformations relating to bigeminism, fused teeth, etc., have a prevalence of 0.5-5%, depending on geographic, racial or genetic factors. This in turn may influence the treatment to be provided in each case. Anomalies in the shape, size and number of teeth are more common in the so-called pediatric genetic syndromes, many of which are associated to mental retardation. The present study describes two clinical cases of similar dental fusion involving a central incisor and comprising different and individualized treatment plans due to the important differences in the characteristics of each patient. The first case corresponded to a healthy 9-year-old boy with a fused upper central incisor and a supernumerary incisor in the second quadrant. The fused tooth presented two independent and converging roots with a single pulp chamber. Endodontic treatment was provided, with dental sectioning and composite reconstruction of the crown. Orthodontic management was reserved for a second stage. The second patient was a 27-year-old male with severe mental retardation of uncertain origin, gingival hyperplasia, a large bilobular upper central incisor, and a total lack of oral hygiene. Treatment in this case was limited to surgical resolution of the periodontal problem and the introduction of an exhaustive prevention program involving instructions for oral hygiene (with implication of the parents and care takers). In conclusion, the development of a management plan in these two cases of fused teeth required due consideration of the degree of patient cooperation, which was severely limited in one case - thereby causing treatment to differ greatly from one individual to another (AU)

Considerations and differences in the treatment of a fused tooth.

Dental malformations relating to bigeminism, fused teeth, etc., have a prevalence of 0.5-5%, depending on geographic, racial or genetic factors. This in turn may influence the treatment to be provided in each case. Anomalies in the shape, size and number of teeth are more common in the so-called pediatric genetic syndromes, many of which are associated to mental retardation. The present study describes two clinical cases of similar dental fusion involving a central incisor and comprising different and individualized treatment plans due to the important differences in the characteristics of each patient. The first case corresponded to a healthy 9-year-old boy with a fused upper central incisor and a supernumerary incisor in the second quadrant. The fused tooth presented two independent and converging roots with a single pulp chamber. Endodontic treatment was provided, with dental sectioning and composite reconstruction of the crown. Orthodontic management was reserved for a second stage. The second patient was a 27-year-old male with severe mental retardation of uncertain origin, gingival hyperplasia, a large bilobular upper central incisor, and a total lack of oral hygiene. Treatment in this case was limited to surgical resolution of the periodontal problem and the introduction of an exhaustive prevention program involving instructions for oral hygiene (with implication of the parents and care takers). In conclusion, the development of a management plan in these two cases of fused teeth required due consideration of the degree of patient cooperation, which was severely limited in one case -- thereby causing treatment to differ greatly from one individual to another.

Sedation in the geriatric patient.

A review is made of the utility of iatrosedation and pharmacological sedation in the dental treatment of elderly patients. The adoption of such measures is required due to the increased prevalence of oral pathology, poorer stress tolerance and frequent association of systemic disease in such patients. A description is made of the recommended psychoactive drug administration routes according to the associated pathology and of the most frequent pharmacological interactions with the background disease. Drug sedation should always be accompanied by psychological measures to minimize the required drug dose, and by correct locoregional anesthesia.

Sedacion en el paciente geriátrico / Sedation in the geriatric patient

Se exponen la utilidad de la yatrosedación y de la sedación farmacológica para el tratamiento odontológico en el paciente anciano, su aplicación es necesaria debido a la mayor prevalencia de patología oral, peor tolerancia al estrés y a la asociación frecuente con patología sistémica. Se describen las vías de administración de psicofármacos más indicada según la patología asociada y a la interrelación farmacológica más frecuente con su patología de base. La fármaco-sedación siempre debe ir acompañada de un manejo psicológico para así minimizar las dosis y de una anestesia loco-regional correcta (AU)

Implants in handicapped patients.

Implantology as an approach for replacing missing teeth has become a generalized practice in recent years. The present study describes the results of placing 67 implants in 18 patients with various degrees of mental and physical impediments. Only four implants were lost, though in all cases fixed-prosthesis oral rehabilitation was achieved -- the implant failure rate (5.6%) being similar to that observed in healthy individuals. A description is provided of the course of different clinical cases illustrating the rehabilitation process, from implant placement to completion of the prosthesis. In our opinion, implantology may constitute a valid management alternative to be taken into consideration in the oral rehabilitation of handicapped patients. The use of implants should be evaluated taking into account the particular characteristics of each individual patient.

An epidemiological study of caries in a group of children with cerebral palsy.

The results of an epidemiological study of caries in a group of 103 children with cerebral palsy between 5 and 20 years of age and treated in Nen Deu Hospital (Barcelona, Spain) are presented. The CAOD (caries, absent teeth, filled teeth) and ICO indices (caries, filled teeth) were evaluated in the permanent and deciduous dentition, respectively.

Síndrome de Coffin Lowry, características odontológicas, revisión de la literatura y presentación de un caso clínico / Coffin-lowry syndrome: odontologic characteristics. Review of the literature and presentation of a clinical case

Se describen las características generales y estomatológicas del Síndrome de Coffin Lowry, características estomatológicas (AU)

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Estudio epidemiológico de la caries en un grupo de niños con parálisis cerebral / an epidemiological study of caries in a group of children with cerebral palsy

Se presentan los resultados de un estudio epidemiológico de la caries en un grupo de 103 niños con parálisis cerebral del Hospital Niño Dios de Barcelona en edades comprendidas entre los 5 y 20 años. Se exploró el índice CAOD en dentición permanente y el Ico en dentición temporal (AU)

Características y tratamiento estomatológico en la trisomía parcial del cromosoma n° 9 / Characteristics and dental treatment of partial trisomy 9

Se describen las características estomatológicas y el tratamiento odontológico realizado a una paciente afecta de una trisomía parcial del par cromosómico número 9. Debido a la profunda deficiencia psico-motriz de la paciente, dicho tratamiento se lleva a cabo en medio hospitalario y bajo anestesia general. El tratamiento incluye exodoncias, periodoncia y odontología conservadora. Dicha trisomía aparece descrita muy raramente en la literatura siendo éste uno de los primeros artículos en describir tanto las características estomatológicas como el tratamiento de la patología oral (AU)