Accuracy and Comprehensiveness in Recording Information of a Web-Based Application for Preoperative Assessment: A Prospective Observational Study.

PURPOSE: Preanestes@s is a web-based application that includes a smart computer-based self-assessment preoperative questionnaire (PreQuest). Preanestes@s enables remote non-telephonic preoperative assessment via a virtual visit. We aimed to determine if the American Society of Anesthesiologists (ASA) physical status classification assigned by PreQuest and virtual visit is comparable with that assigned by face-to-face assessment, and to determine the accuracy of Preanestes@s in recording complementary preoperative information. DESIGN: Prospective, observational, paired study. METHODS: This study was conducted in a tertiary teaching hospital. A total of 510 adult patients scheduled for surgery were consecutively recruited. Of these, 220 patients were included in the analysis of ASA grade agreement. FINDINGS: PreQuest and virtual visit showed higher predictive value than face-to-face assessment in detecting patients with ASA grades 1 to 2. Face-to-face assessment showed the highest rate of false negatives (ASA 3-4 misclassified as ASA 1-2), with a sensitivity of 44.2% versus 69.8% and 50% for PreQuest and virtual visit, respectively. Virtual visit showed the highest agreement with the ASA grade assigned by a panel of experts (kappa index 0.52, 95% confidence interval 0.15-0.89). PreQuest and virtual visit offered a more comprehensive registry of anthropometric data, more detailed record of chronic diseases condition, and more accurate registry of patients' treatments (virtual visit > PreQuest > face-to-face assessment). CONCLUSIONS: The combined use of PreQuest and virtual visit offers a better performance in assigning the ASA grade for non-complex patients and a more accurate and detailed record of complementary information. This finding suggests the feasibility of Preanestes@ as a tool for preoperative assessment.

Case Report of a Patient Treated With Acenocumarol Awaiting Orthotopic Liver Transplant: Perioperative Coagulation Management and Risk for Hepatic Artery Thrombosis.

BACKGROUND: End-stage liver disease is associated with a concomitant reduction of pro- and anticoagulant factors that typically leads to rebalanced hemostasis. This rebalanced hemostasis can be easily disturbed, encountering both hemostasis-related bleeding episodes and thrombotic events. METHODS: This article reports a case of a 52-year-old man diagnosed with portal vein thrombosis and treated with Acenocumarol. The patient received ortothopic liver transplant. The preprocedure international normalized ratio was 3.5. A transfusion of 2000 units of prothrombin complex concentrate was indicated by Hematology. RESULTS: Repeated intra- and postoperative hepatic artery thrombosis resulted in graft loss and patient retransplantation in first 24 hours. CONCLUSIONS: The new concept of rebalanced hemostasis in these patients forces us to change our clinical decisions in preoperative coagulation management, avoiding old practices based on the traditional model such as transfusion guided by international normalized ratio and platelet count, among others that will be analyzed in present work.

Hepatic Artery Thrombosis After Orthotopic Liver Transplant: Experience in the Last 10 Years.

BACKGROUND: Hepatic artery thrombosis (HAT) is the second cause of graft failure, after primary disfunction. It has a significant morbidity, with a retransplant and mortality rate in early hepatic artery thrombosis of 50%. The incidence of this event goes from 2% to 9% in the adult population. METHODS: The objective is to assess the incidence of HAT in a third-level hospital. The study design is an observational retrospective study, collecting data of the transplant recipient from 2010 to 2020. RESULTS: Incidence of HAT was 5.33% (39/732). A statistical difference was found with the blood intraoperative administration (P = .002) and with the presence of anatomic abnormalities in the hepatic artery between the HAT and the non-HAT group. We did not find any statistical difference with portal thrombosis (P = .73) between the groups. CONCLUSIONS: HAT is a fatal complication after an orthotopic liver transplant, which can lead to graft loss and even recipient death. For these reasons, we should early identify risk factors associated with this event early and try to minimize them to avoid the devastating consequences.

Molecular concentration of deoxyHb in human prefrontal cortex predicts the emergence and suppression of consciousness.

This is the first study to use fNIRS to explore anaesthetic depth and awakening during surgery with general anaesthesia. A 16 channel continuous wave (CW) functional near-infrared system (fNIRS) was used to monitor PFC activity. These outcomes were compared to BIS measures. The results indicate that deoxyHb concentration in the PFC varies during the suppression and emergence of consciousness. During suppression, deoxyHb levels increase, signalling the deactivation of the PFC, while during emergence, deoxyHb concentration drops, initiating PFC activation and the recovery of consciousness. Furthermore, BIS and deoxyHb concentrations in the PFC display a high negative correlation throughout the different anaesthetic phases. These findings suggest that deoxyHb could be a reliable marker for monitoring anaesthetic depth, and that the PFC intervenes in the suppression and emergence of consciousness.

Sedación para la realización de ecobroncoscopia lineal / Sedation for linear endobronchial ultrasound

Introducción: La ecobroncoscopia es una nueva técnica diagnóstica en la detección del cáncer de pulmón. Permite realizar la punción aspirativa con aguja fina de adenopatías mediastínicas e hiliares, lo que ayuda a determinar el estadio de la enfermedad. Es una técnica mínimamente invasiva que se realiza bajo sedación consciente y que no requiere ingreso. Objetivos: Presentación de un caso clínico en el que se emplea esta nueva técnica diagnóstica y exposición del manejo anestésico fuera del área quirúrgica. Material y métodos: Exposición del caso clínico. Conclusiones: El principal objetivo de la sedación durante la realización de esta prueba es la correcta analgesia acompañada de la inmovilidad completa del paciente, todo esto manteniendo la estabilidad hemodinámica y respiratoria. El anestesiólogo debe proporcionar al paciente el mayor confort y seguridad posibles, facilitando la labor del médico explorador. La comunicación entre especialistas es fundamental.

Introduction: Endobronchial ultrasound is a new diagnostic technique for the detection of lung cancer. The technique enables a fine needle aspiration of mediastinal and hilar adenopathies to help stage the pathology. This is a minimally invasive technique performed under conscious sedation and does not require admission. Objectives: Presenting a clinical case using this new diagnostic technique and illustrate the anesthetic management outside the operating room. Material and methods: Presentation of the clinical case. Conclusions: The main objective of sedating the patient undergoing the procedure is proper analgesia and total patient immobility, while maintaining hemodynamic and respiratory stability. The anesthetist should provide maximum comfort and safety to the patient, facilitating the work of de physician doing the exploration. Communication between the two specialists is of the essence.