Assuntos
Infecções por Citomegalovirus/diagnóstico por imagem , Endossonografia , Gastrite/diagnóstico por imagem , Linite Plástica/diagnóstico por imagem , Neoplasias Gástricas/diagnóstico por imagem , Anticorpos Antivirais/análise , Biópsia , Citomegalovirus/imunologia , Infecções por Citomegalovirus/patologia , Infecções por Citomegalovirus/virologia , Diagnóstico Diferencial , Mucosa Gástrica/patologia , Mucosa Gástrica/virologia , Gastrite/patologia , Gastrite/virologia , Gastroscopia , Humanos , Linite Plástica/patologia , Masculino , Pessoa de Meia-Idade , Neoplasias Gástricas/patologiaRESUMO
OBJECTIVES: We report the efficacy of alteplase (a recombinant tissue plasminogen activator) with heparin or heparin alone in the treatment of acute thrombosis of the portal venous system. METHODS: Ten consecutive patients with acute portal venous system thrombosis were studied. Five patients were treated with alteplase and heparin, and the remaining 5 patients, who were asymptomatic or had a contraindication to alteplase, were treated with heparin alone. RESULTS: In 3 of the 5 patients treated with alteplase, ultrasonography showed total resolution of the thrombus; the remaining 2 had partial resolution of the thrombus. In 4 of the 5 patients treated with heparin alone, ultrasonography showed total resolution of the thrombus, and no change in one. No bleeding occurred. CONCLUSION: Treatment with heparin can result in complete recanalisation of acute portal venous system thrombosis. These data suggest that combined therapy with systemic alteplase does not increase the efficacy of heparin.