Effectiveness of prevention exercises protocol among office workers with symptoms of carpal tunnel syndrome.

OBJECTIVES: Carpal tunnel syndrome (CTS) is common among office workers and limits functional hand ability and the ability to work. Carpal tunnel syndrome prevention programs implementation are still insufficient among office workers. In view of the fact that physical activity is the best method of preventing musculoskeletal complaints the aim of the study was to evaluate the effectiveness of prevention exercises protocol for hand and wrist pain among office workers. MATERIAL AND METHODS: Study group consists form 62 office workers, reporting complaints of hand and wrist pain. Exercise group it was 49 subjects who performed the exercise protocol and the non-exercise group consisted of 13 subjects. An exercises program, consisting of 7 exercises. The program was planned for daily routine during 8 weeks. The effectiveness of the exercise program was assessed by physical parameters (hand grip and pinch grip strength, force of forearm muscles) and questionnaires (Visual Analog Scale pain scale, Carpal Tunnel Syndrome Symptom Severity Scale, and Carpal Tunnel Syndrome Functional Status Scale functional hand assessment questionnaires) were performed. Assessment was performed before and after the intervention. RESULTS: Statistical analysis of the data showed significant changes in the value of measured hand grip of the right hand (Z = -2.85, p < 0.01). For pinch grip, changes were significant for both the right (Z = -2.12, p < 0.05) and the left hands (Z = -2.35, p < 0.05). Functional performance improved significantly in bought groups. There was no statistically significant change in the intensity of experienced pain. CONCLUSIONS: The results of the study indicate that performing a preventive exercise program regularly has an effect on increasing forearm muscle strength in a group of office workers. Office workers with symptoms of CTS who exercised regularly had higher results in hand grip and pincer grip strength. Exercises do not affect the level of pain complaints, which may indicate a more complex etiology of pain perception in this study group. Int J Occup Med Environ Health. 2024;37(1):45-57.

Electroactive molecularly imprinted polymer nanoparticles for selective glyphosate determination.

Redox-active molecularly imprinted polymer nanoparticles selective for glyphosate, MIP-Gly NPs, were devised, synthesized, and subsequently integrated onto platinum screen-printed electrodes (Pt-SPEs) to fabricate a chemosensor for selective determination of glyphosate (Gly) without the need for redox probe in the test solution. That was because, ferrocenylmethyl methacrylate was added to the polymerization mixtures during the NPs synthesis so that the resulting MIP-Gly NPs contained covalently immobilized ferrocenyl moieties as the reporting redox ingredient, conferring these NPs with electroactive properties. MIP-Gly NPs of four different compositions were evaluated. The herein described approach represents a simple and effective way to endow MIP NPs with electrochemical reporting capabilities with neither the need to functionalize them post-synthesis nor to use electrochemical mediators present in the tested solution during the analyte determinations. MIP-Gly NPs synthesized using allylamine and squaramide-based monomers appeared most selective to Gly. The Pt-SPEs modified with MIP-Gly NPs were characterized with differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS). Changes in the DPV peak originating from the oxidation of the ferrocenyl moieties in these MIP-Gly NPs served as the analytical signal. The DPV limit of detection and the linear dynamic concentration range for Gly were 3.7 pM and 25 pM-500 pM, respectively. Moreover, the selectivity of the fabricated chemosensors was sufficiently high to determine Gly successfully in spiked river water samples.

[Changes in neuromuscular conduction of workers depending on age]. / Zmiany przewodnictwa nerwowo-miesniowego pracowników w zaleznosci od wieku.

BACKGROUND: The research was conducted to determine the effect of age on potential functional changes occurring through the transmission of nerve impulses in the motor nerves supplying selected muscles of the lower limb. The nerve conduction parameters in the lower limb were measured, as well as the ability to control muscle tension with pressure on the foot pedal. MATERIAL AND METHODS: The study included a group of 54 men, differentiated by age. During the research, the speed of nerve conduction, amplitude and latency of the motor response in the tibial and peroneal nerves were measured. During the RAMP-contraction test, the EMG signal was recorded from the tibialis anterior muscles and the gastrocnemius muscles of the medial head. RESULTS: The results of the research showed that with age the ability to control muscle tone decreases, the speed of transmission of electrical impulses decreases, the motor response is delayed and its amplitude is significantly lower than in the case of younger people. CONCLUSIONS: The deterioration of neuromuscular conduction observed with age and a reduction in the ability to control the generated value of muscle strength may result in a deterioration of the ability to operate equipment or drive vehicles. From the point of view of prolonging the activity in working life, identifying all factors limiting the functioning of an older employee in the work environment may be the basis for creating guidelines and recommendations helpful in the design of devices and workstations for older employees. Med Pr. 2022;73(5):417-25.

An advantageous application of molecularly imprinted polymers in food processing and quality control.

In the global market era, food product control is very challenging. It is impossible to track and control all production and delivery chains not only for regular customers but also for the State Sanitary Inspections. Certified laboratories currently use accurate food safety and quality inspection methods. However, these methods are very laborious and costly. The present review highlights the need to develop fast, robust, and cost-effective analytical assays to determine food contamination. Application of the molecularly imprinted polymers (MIPs) as selective recognition units for chemosensors' fabrication was herein explored. MIPs enable fast and inexpensive electrochemical and optical transduction, significantly improving detectability, sensitivity, and selectivity. MIPs compromise durability of synthetic materials with a high affinity to target analytes and selectivity of molecular recognition. Imprinted molecular cavities, present in MIPs structure, are complementary to the target analyte molecules in terms of size, shape, and location of recognizing sites. They perfectly mimic natural molecular recognition. The present review article critically covers MIPs' applications in selective assays for a wide range of food products. Moreover, numerous potential applications of MIPs in the food industry, including sample pretreatment before analysis, removal of contaminants, or extraction of high-value ingredients, are discussed.

"Gate Effect" in p-Synephrine Electrochemical Sensing with a Molecularly Imprinted Polymer and Redox Probes.

The "gate effect" mechanism for conductive molecularly imprinted polymer (MIP) film coated electrodes was investigated in detail. It was demonstrated that the decrease of the DPV signal for the Fe(CN)64-/Fe(CN)63- redox probe with the increase of the p-synephrine target analyte concentration in solution at the polythiophene MIP-film coated electrode did not originate from swelling or shrinking of the MIP film, as it was previously postulated, but from changes in the electrochemical process kinetics. The MIP-film coated electrode was examined with cyclic voltammetry (CV), differential pulse voltammetry (DPV), electrochemical impedance spectroscopy (EIS), and surface plasmon resonance (SPR). The MIP-film thickness in the absence and in the presence of the p-synephrine analyte was examined with in situ AFM imaging. Moreover, it was demonstrated that doping of the MIP film was not affected by p-synephrine binding in MIP-film molecular cavities. It was concluded that the "gate effect" was most likely caused by changes in radical cation (polaron) mobility in the film.

Leg strength and power in Polish striker soccer players.

PURPOSE: The main goal of the present study was to examine muscle strength and power of dominant and non-dominant leg, knee extensors and flexors, and their correlations with jumping performances in soccer players. A secondary aim was to evaluate muscle sense. METHODS: 31 male professional strikers (age 20.9 ± 2.3 years, body mass 75.1 ± 6.6 kg, body height 179.5 ± 4.7 cm) participated in the study. The power output of lower extremities and the height of rise of the body mass centre during vertical jumps were measured using a force plate. The maximum muscle torque of the flexors and extensors of the knee were measured under isometric conditions using a special isometric torquemeter. Force sense was measured in isometric conditions in two tests: (a) fifty percent of the maximal voluntary contraction was set as a value of target force and the participants were instructed to reproduce the target force, (b) the participants attempted to develop a torque reproducing a sine course within the range of 10 to 50% of MVC performed. RESULTS: A direct relationship was observed between the peak muscle torque in knee extensors developed during isokinetic contraction at all velocities and power and height of three types of vertical jumps ( p <0.05). No correlation was observed between jumping performance and muscle torque under isometric condition. No differences were found in strength and jumping abilities as well as in force sense between dominant and non-dominant legs. CONCLUSIONS: This study offered a comprehensive and complete evaluation of leg muscle strength, sense and power, with the use of using force plate and isokinetic dynamometry.

Nanostructured molecularly imprinted polymers for protein chemosensing.

Molecularly imprinted polymers (MIPs) are tailor made recognition materials that can mimic biological receptors. If used as recognition units for chemosensors fabrication, they outperform natural receptors with their durability, chemical stability, and low production costs. Novel techniques of MIP deposition as thin films, surface development, and introduction of additional properties are very much demanded in terms of selective and sensitive chemosensors fabrication. Therefore, in recent years a particular attention has been paid to syntheses of nanostructured MIP films and MIP nanoparticles. The present brief review surveys novel achievements in the field of MIP nanostructures and their application for determination of protein analytes.

Molecularly Imprinted Polymer Chemosensor for Selective Determination of an N-Nitroso-l-proline Food Toxin.

A molecularly imprinted polymer (MIP)-based chemosensor for the selective determination of a chosen toxin, N-nitroso-l-proline (Pro-NO), was devised and fabricated. By means of DFT, the structure of the pre-polymerization (functional monomer)-template complex was modeled. This complex was then potentiodynamically electropolymerized in the presence of cross-linking monomer to form a MIP-Pro-NO thin film. Next, the Pro-NO template was extracted from MIP-Pro-NO with 0.1 m NaOH. Piezoelectric microgravimetry (PM) on an electrochemical quartz crystal microbalance and electrochemical (differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS)) techniques were used to transduce binding of Pro-NO to molecular cavities of the MIP-Pro-NO. With DPV and EIS chemosensing, the limits of detection (LODs) were about 80.9 and 36.9 nM Pro-NO, respectively; and the selectivity coefficients for urea, glucose, creatinine, and adrenalin interferences were 6.6, 13.2, 2.1, and 2.0, respectively, with DPV as well as 2.3, 2.0, 3.3, and 2.5, respectively, with EIS. With PM under flow injection analysis conditions, the LOD was 10 µm Pro-NO. The MIP-Pro-NO chemosensor detectability and selectivity with respect to interferences were sufficiently high to determine Pro-NO in protein-providing food products.

Measuring the force of punches and kicks among combat sport athletes using a modified punching bag with an embedded accelerometer.

The main aim of the study was to design a new system to measure punching and kicking forces as well as reaction times in combat sport athletes. In addition, the study examined whether there were any intergender differences in the force of punches thrown by boxers and kicking forces delivered by taekwondo athletes. Boxers (male, n = 13; female, n = 7) were examined for the force of single straight punches and taekwondo athletes (male, n = 14; female, n = 14) for force of single Apdolio and Dwit Chagi kicks. The punching bag was equipped with acceleration transducers and gyroscopes embedded in a cylinder covered with a layer to absorb shock as well as a set of colour signal diodes. Value of the punching bag's acceleration was used for calculating: strike force; the punching location on the bag; and time of a strike. The relative error of force calculation was 3%; the relative error in acceleration measurement was less than 1%. The force of a straight rear-hand punch was greater than the force of a lead-hand punch among male and female boxers. The force of Apdolio kick delivered with a rear leg was greater compared to a lead leg among female and male taekwondo athletes. Significant gender differences were noticed in the force in both types of kicks. In boxers, intergender differences were reported only for the force of a punch thrown with the rear hand. Based on these findings, it was concluded that the modified punching bag is a good diagnostic tool for combat sports.