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Nat Prod Res ; 34(24): 3545-3547, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30835550

RESUMO

The aim of the present study was to evaluate the phenolic contents in capsule and root methanolic extracts of Euphorbia retusa followed by identification of phenolic on capsule extracts through high-performance liquid chromatography (HPLC- DAD) for the first time. Likewise, the antioxidant activity of both extracts was investigated by using Cupric reducing antioxidant capacity (CUPRAC). The result implies that E. retusa capsules have the highest phenolic and flavonoid contents with 105.33 ± 7.75 µg GAE.mg-1 extract 19.95 ± 0.96 µg QEs.mg-1 extract; respectively and the highest activity in CUPRAC assay with epigallocatechin 3-O-Gallate was the major flavonoid. Thus, our findings indicate that E. restusa capsules may be valorized in industrial fields.


Assuntos
Antioxidantes/química , Antioxidantes/farmacologia , Euphorbia/química , Fenóis/farmacologia , Extratos Vegetais/farmacologia , Cápsulas , Catequina/análogos & derivados , Catequina/análise , Cromatografia Líquida de Alta Pressão , Avaliação Pré-Clínica de Medicamentos , Flavonoides/análise , Fenóis/análise , Fenóis/química , Extratos Vegetais/química
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