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1.
Comput Biol Med ; 172: 108191, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38457932

RESUMO

Bicuspid aortic valve (BAV), the most common congenital heart disease, is prone to develop significant valvular dysfunction and aortic wall abnormalities such as ascending aortic aneurysm. Growing evidence has suggested that abnormal BAV hemodynamics could contribute to disease progression. In order to investigate BAV hemodynamics, we performed 3D patient-specific fluid-structure interaction (FSI) simulations with fully coupled blood flow dynamics and valve motion throughout the cardiac cycle. Results showed that the hemodynamics during systole can be characterized by a systolic jet and two counter-rotating recirculation vortices. At peak systole, the jet was usually eccentric, with asymmetric recirculation vortices and helical flow motion in the ascending aorta. The flow structure at peak systole was quantified using the vorticity, flow rate reversal ratio and local normalized helicity (LNH) at four locations from the aortic root to the ascending aorta. The systolic jet was evaluated with the peak velocity, normalized flow displacement, and jet angle. It was found that peak velocity and normalized flow displacement (rather than jet angle) gave a strong correlation with the vorticity and LNH in the ascending aorta, which suggests that these two metrics could be used for clinical noninvasive evaluation of abnormal blood flow patterns in BAV patients.


Assuntos
Doença da Válvula Aórtica Bicúspide , Doenças das Valvas Cardíacas , Humanos , Valva Aórtica/anormalidades , Doenças das Valvas Cardíacas/diagnóstico por imagem , Aorta , Hemodinâmica/fisiologia
2.
Heliyon ; 8(8): e10017, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35928101

RESUMO

In the present work, a vertical axis turbine with straight blades was analyzed through a numerical simulation in three dimensions, the performance of the turbine was studied while synthetic jets were used as an active flow control method. To carry out the simulations, the Unsteady Reynolds Averaged Navier-Stokes (URANS) equations were solved on Star CCM+, through the k-ω SST turbulence model. The dynamics of the turbine movement were described using the Overset Mesh technique, capturing the transient characteristics of the flow field. Hydrodynamic coefficients and vorticity fields were obtained to describe the flow behaviour, and the results were compared with two-dimensional simulations of the same system. Turbine performance with tangential synthetic jets located on the intrados and extrados of the airfoil shows an increase in the torque and power output of the turbine. Moreover, using simple estimates, synthetic jets used less power than the increment in power generated at the turbine shaft, showing that efficiency of the turbine increases with the use of synthetic jets. However, the increment in the turbine performance is not as high as in previous two-dimensional studies reported in the literature.

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