The impact of generative artificial intelligence on socioeconomic inequalities and policy making.

Generative artificial intelligence (AI) has the potential to both exacerbate and ameliorate existing socioeconomic inequalities. In this article, we provide a state-of-the-art interdisciplinary overview of the potential impacts of generative AI on (mis)information and three information-intensive domains: work, education, and healthcare. Our goal is to highlight how generative AI could worsen existing inequalities while illuminating how AI may help mitigate pervasive social problems. In the information domain, generative AI can democratize content creation and access but may dramatically expand the production and proliferation of misinformation. In the workplace, it can boost productivity and create new jobs, but the benefits will likely be distributed unevenly. In education, it offers personalized learning, but may widen the digital divide. In healthcare, it might improve diagnostics and accessibility, but could deepen pre-existing inequalities. In each section, we cover a specific topic, evaluate existing research, identify critical gaps, and recommend research directions, including explicit trade-offs that complicate the derivation of a priori hypotheses. We conclude with a section highlighting the role of policymaking to maximize generative AI's potential to reduce inequalities while mitigating its harmful effects. We discuss strengths and weaknesses of existing policy frameworks in the European Union, the United States, and the United Kingdom, observing that each fails to fully confront the socioeconomic challenges we have identified. We propose several concrete policies that could promote shared prosperity through the advancement of generative AI. This article emphasizes the need for interdisciplinary collaborations to understand and address the complex challenges of generative AI.

Observing the earth from space: Does a virtual reality overview effect experience increase pro-environmental behaviour?

Astronauts (and recently businessmen) often express a renewed sense of responsibility for taking care of the environment, after observing the overwhelming beauty of Earth from space. Despite recent attention for this "overview effect", it is unclear whether experiencing the effect directly impacts pro-environmental behaviour. Using a virtual reality experience, the current research tests in two experimental studies the direct impact of an immersive overview effect experience on both short-term and longer term subsequent pro-environmental behaviours (donating to an environmental NGO, consuming less diary and meat). Furthermore, it investigates whether the technological immersiveness of the VR experience amplifies the effect, and the mediating role of connectedness to nature. Results show no effects of the short (7 minutes) overview effect VR video on pro-environmental behaviour (Study 1). For the longer video (15 minutes, Study 2), the results showed that the most immersive experience (video featuring meditative music and voice-over) appeared to increase connection with nature and higher donation amounts to an eco-NGO, but not significantly. No effects were found for subsequent meat and dairy consumption behaviours (measured on day 2, 4, and 6). These findings contribute to a deeper understanding of the specific features determining the effectiveness of the overview effect experiences on actual pro-environmental behaviour, providing important insights to businesses and educational institutions.

Love and hate do not modulate the attentional blink but improve overall performance.

How may feelings of love and hate impact people's attention? We used a modified Attentional Blink (AB) task in which 300 participants were asked to categorise a name representing a person towards whom they felt either hate, love, or neutral (first target) plus identify a number word (second target), both embedded in a rapidly presented stream of other words. The lag to the second target was systematically varied. Contrary to our hypothesis, results revealed that both hated and loved names resulted in higher accuracy for the second target than neutral names, which was largely independent of lag. Also, there we observed no sustained transfer effects of love and hate onto neutral name trials. The findings differ from prior research on attentional blink and transient, non-personal, stimulus-driven emotions, suggesting that interpersonal feelings activate different attention-relevant mechanisms. Relevant to future research, we speculate that love and hate are motivators of goal-directed behaviour that facilitate subsequent information processing.

How perceived coercion polarizes unvaccinated people: The mediating role of conspiracy beliefs.

During the COVID-19 pandemic, different policies were implemented to increase vaccination uptake. Meanwhile, conspiracy theories spread widely, and vaccinated versus unvaccinated people increasingly polarized against each other. This study examined the associations between perceived vaccination coercion, conspiracy beliefs and polarization. We tested the relationship of vaccination status with perceived vaccination coercion, conspiracy beliefs, and polarization, with a total sample size of N = 1202 (n = 400 in China, n = 401 in the US, and n = 401 in the UK), among them n = 603 were vaccinated and n = 599 were unvaccinated. As pre-registered, unvaccinated people perceived more vaccination coercion and endorsed more conspiracy theories. Conspiracy mentality was positively related to perceived coercion. Contrary to our hypotheses, vaccinated people were more polarized toward unvaccinated people than vice versa. Finally, conspiracy beliefs mediated the link between perceived coercion and polarization among unvaccinated people.

A synthesis of evidence for policy from behavioural science during COVID-19.

Scientific evidence regularly guides policy decisions1, with behavioural science increasingly part of this process2. In April 2020, an influential paper3 proposed 19 policy recommendations ('claims') detailing how evidence from behavioural science could contribute to efforts to reduce impacts and end the COVID-19 pandemic. Here we assess 747 pandemic-related research articles that empirically investigated those claims. We report the scale of evidence and whether evidence supports them to indicate applicability for policymaking. Two independent teams, involving 72 reviewers, found evidence for 18 of 19 claims, with both teams finding evidence supporting 16 (89%) of those 18 claims. The strongest evidence supported claims that anticipated culture, polarization and misinformation would be associated with policy effectiveness. Claims suggesting trusted leaders and positive social norms increased adherence to behavioural interventions also had strong empirical support, as did appealing to social consensus or bipartisan agreement. Targeted language in messaging yielded mixed effects and there were no effects for highlighting individual benefits or protecting others. No available evidence existed to assess any distinct differences in effects between using the terms 'physical distancing' and 'social distancing'. Analysis of 463 papers containing data showed generally large samples; 418 involved human participants with a mean of 16,848 (median of 1,699). That statistical power underscored improved suitability of behavioural science research for informing policy decisions. Furthermore, by implementing a standardized approach to evidence selection and synthesis, we amplify broader implications for advancing scientific evidence in policy formulation and prioritization.

Intravenous Levothyroxine for Unstable Brain-Dead Heart Donors.

BACKGROUND: Hemodynamic instability and myocardial dysfunction are major factors preventing the transplantation of hearts from organ donors after brain death. Intravenous levothyroxine is widely used in donor care, on the basis of observational data suggesting that more organs may be transplanted from donors who receive hormonal supplementation. METHODS: In this trial involving 15 organ-procurement organizations in the United States, we randomly assigned hemodynamically unstable potential heart donors within 24 hours after declaration of death according to neurologic criteria to open-label infusion of intravenous levothyroxine (30 µg per hour for a minimum of 12 hours) or saline placebo. The primary outcome was transplantation of the donor heart; graft survival at 30 days after transplantation was a prespecified recipient safety outcome. Secondary outcomes included weaning from vasopressor therapy, donor ejection fraction, and number of organs transplanted per donor. RESULTS: Of the 852 brain-dead donors who underwent randomization, 838 were included in the primary analysis: 419 in the levothyroxine group and 419 in the saline group. Hearts were transplanted from 230 donors (54.9%) in the levothyroxine group and 223 (53.2%) in the saline group (adjusted risk ratio, 1.01; 95% confidence interval [CI], 0.97 to 1.07; P = 0.57). Graft survival at 30 days occurred in 224 hearts (97.4%) transplanted from donors assigned to receive levothyroxine and 213 hearts (95.5%) transplanted from donors assigned to receive saline (difference, 1.9 percentage points; 95% CI, -2.3 to 6.0; P<0.001 for noninferiority at a margin of 6 percentage points). There were no substantial between-group differences in weaning from vasopressor therapy, ejection fraction on echocardiography, or organs transplanted per donor, but more cases of severe hypertension and tachycardia occurred in the levothyroxine group than in the saline group. CONCLUSIONS: In hemodynamically unstable brain-dead potential heart donors, intravenous levothyroxine infusion did not result in significantly more hearts being transplanted than saline infusion. (Funded by Mid-America Transplant and others; ClinicalTrials.gov number, NCT04415658.).

Adaptations to infer fitness interdependence promote the evolution of cooperation.

The evolution of cooperation is a major question in the biological and behavioral sciences. While most theoretical studies model cooperation in the context of an isolated interaction (e.g., a Prisoner's Dilemma), humans live in heterogeneous social environments, characterized by large variations in fitness interdependence-the extent to which one's fitness is affected by others. Theoretical and experimental work indicates that humans can infer, and respond to, variations in interdependence. In a heterogeneous ancestral environment, these psychological mechanisms to infer fitness interdependence could have provided a selective advantage, allowing individuals to maximize their fitness by deciding when and with whom to cooperate. Yet, to date, the link between cognitive inference, variation in fitness interdependence, and cooperation remains unclear. Here we introduce a theoretical framework to study the evolution of inference and cooperation in heterogeneous social environments, where individuals experience interactions with varying levels of corresponding interests. Using a combination of evolutionary game theory and agent-based modeling, we model the evolution of adaptive agents, who incur a cost to infer interdependence, in populations of fixed-behavior agents who always cooperate or defect. Our results indicate that natural selection could promote the evolution of psychological mechanisms to infer fitness interdependence, provided that there is enough variation in fitness interdependence to offset the cost of inference. Under certain conditions, the fixation of adaptive agents results in higher levels of cooperation. This depends crucially on the type of inference performed and the features of the interdependence landscape.

Reputation Reminders: When do Eye Cues Promote Prosocial Behavior?

The watching eyes effect has gained significant attention in recent years both from scientists and from policy makers and professionals in the field. The phenomenon posits that the mere presence of eye cues can promote prosocial behavior. However, there is a growing debate about the generality of the effect across various measures and contexts. This review seeks to combine various distinct -and formerly isolated- perspectives by identifying four key components for effective interventions based on the watching eyes effect: Anonymity, crowdedness, costs, and exposure. Eye cues need to reduce perceived anonymity, be placed in non-crowded places, target low-cost prosocial acts and appear for a short amount of time. Next to these conditions, we discuss implications for other cues to reputation and recommend directions that will stimulate further research and applications in society.

The moral significance of prosstecting environmental and cultural objects.

A powerful avenue through which to promote the preservation of the natural and cultural environment is to afford cultural and environmental objects moral significance. In this research, we examine a range of factors that may give rise to moral concern regarding the protection of culturel and environmental objects as ends in themselves. In this way, we also extend theorizing and evidence beyond a focus on sentience as a focal determinant of moral significance Across five studies we show that non-sentient objects can sometimes be viewed as possessing intrinsically valuable properties that afford them moral standing (independent of their extrinsic/means-end value or any perception of their capacity to think and feel). People judge it morally wrong to harm things that are beautiful, sacred, rare, or old, and this cannot be explained merely by their usefulness or economic value. Our findings provide new insight into ways to elevate the protection of natural and cultural objects to an issue of moral significance, and suggest avenues through which to motivate the preservation of a natural and cultural environments.

Enriching Psychology by Zooming Out to General Mindsets and Practices in Natural Habitats.

Psychology has been "zooming in" on individuals, dyads, and groups with a narrow lens to the exclusion of "zooming out," which involves placing the targeted phenomena within more distal layers of influential context. Here, we plea for a paradigm shift. Specifically, we showcase largely hidden scientific benefits of zooming out by discussing worldwide evidence on inhabitants' habitual adaptations to colder-than-temperate and hotter-than-temperate habitats. These exhibits reveal two different types of theories. Clement-climate perspectives emphasize that generic common properties of stresses from cold and hot temperatures elicit similar effects on personality traits and psychosocial functioning. Cold-versus-heat perspectives emphasize that specific unique properties of stresses from cold and hot habitats elicit different effects on phenomena, such as speech practices and intergroup discrimination. Both zooming-out perspectives are then integrated into a complementary framework that helps identify explanatory mechanisms and demonstrates the broader added value of embedding zooming-in approaches within zooming-out approaches. Indeed, zooming out enriches psychology.

Lost in between crises: How do COVID-19 threats influence the motivation to act against climate change and the refugee crisis?

While the COVID-19 pandemic has been found to undermine mental health, it is unclear how it may impact individuals' motivation to tackle other global crises. There are at least two perspectives on how COVID-19 might psychologically impact how people respond to other global crises. The finite-pool-of-worry hypothesis suggests that worrying about one issue might diminish worry about other issues since individuals have a limited capacity of worry. Conversely, the affect-generalization hypothesis advocates that worry about an issue might generalize to other issues and increase general levels of worry. To test these competing hypotheses, the present research investigated how threats activated by the COVID-19 pandemic might affect individuals' interest in and motivation to address climate change (Study 1) and the refugee crisis (Study 2) by assessing pro-environmental behavior and prosocial behavior toward refugees, respectively. The results showed that exposure to COVID-19 threats elevated anxiety levels, and trait anxiety, psychological distance, and future orientation moderated this effect. While COVID-19 threats did not influence pro-environmental and prosocial behavior and intentions, exploratory analyses uncovered that being psychologically closer to COVID-19 might predict an increase in pro-environmental and prosocial behavior and intentions, pointing to the affect-generalization hypothesis.

Corrupt third parties undermine trust and prosocial behaviour between people.

Corruption is a pervasive phenomenon that affects the quality of institutions, undermines economic growth and exacerbates inequalities around the globe. Here we tested whether perceiving representatives of institutions as corrupt undermines trust and subsequent prosocial behaviour among strangers. We developed an experimental game paradigm modelling representatives as third-party punishers to manipulate or assess corruption and examine its relationship with trust and prosociality (trust behaviour, cooperation and generosity). In a sequential dyadic die-rolling task, the participants observed the dishonest behaviour of a target who would subsequently serve as a third-party punisher in a trust game (Study 1a, N = 540), in a prisoner's dilemma (Study 1b, N = 503) and in dictator games (Studies 2-4, N = 765, pre-registered). Across these five studies, perceiving a third party as corrupt undermined interpersonal trust and, in turn, prosocial behaviour. These findings contribute to our understanding of the critical role that representatives of institutions play in shaping cooperative relationships in modern societies.

Reputation Reminders: When do Eye Cues Promote Prosocial Behavior?

The watching eyes effect has gained significant attention in recent years both from scientists and from policy makers and professionals in the field. The phenomenon posits that the mere presence of eye cues can promote prosocial behavior. However, there is a growing debate about the generality of the effect across various measures and contexts. This review seeks to combine various distinct -and formerly isolated- perspectives by identifying four key components for effective interventions based on the watching eyes effect: Anonymity, crowdedness, costs, and exposure. Eye cues need to reduce perceived anonymity, be placed in non-crowded places, target low-cost prosocial acts and appear for a short amount of time. Next to these conditions, we discuss implications for other cues to reputation and recommend directions that will stimulate further research and applications in society. (AU)

Social mindfulness predicts concern for nature and immigrants across 36 nations.

People cooperate every day in ways that range from largescale contributions that mitigate climate change to simple actions such as leaving another individual with choice - known as social mindfulness. It is not yet clear whether and how these complex and more simple forms of cooperation relate. Prior work has found that countries with individuals who made more socially mindful choices were linked to a higher country environmental performance - a proxy for complex cooperation. Here we replicated this initial finding in 41 samples around the world, demonstrating the robustness of the association between social mindfulness and environmental performance, and substantially built on it to show this relationship extended to a wide range of complex cooperative indices, tied closely to many current societal issues. We found that greater social mindfulness expressed by an individual was related to living in countries with more social capital, more community participation and reduced prejudice towards immigrants. Our findings speak to the symbiotic relationship between simple and more complex forms of cooperation in societies.

Adverse outcomes with extracorporeal adsorbent blood treatments in toxic systemic inflammation: a perspective on possible mechanisms.

BACKGROUND: Extracorporeal blood purification (EBP) treatments may be used in patients with sepsis and related conditions to mitigate toxic systemic inflammation, prevent or reverse vital organ injury, and improve outcome. These treatments lack demonstrable efficacy, but are generally considered safe. However, since late 2020, four clinical studies of EBP treatment using adsorbent devices in inflammatory disease reported significantly increased patient mortality associated with the adsorbent treatments. Criticisms of study design and execution were published, but revealed no decisive flaws. None of these critiques considered possible toxic effects of the adsorbent treatments per se. PERSPECTIVE AND CONCLUSION: In adsorbent EBP treatment of systemic inflammatory disease the adsorbent media are deployed in patient blood or plasma flow for the purpose of broad spectrum, non-specific adsorptive removal of inflammatory mediators. Adsorption and sequestration of inflammatory mediators by adsorbent media is intended to reduce mediator concentrations in circulating blood and neutralize their activity. However, in the past two decades developments in both biomedical engineering and the science of cytokine molecular dynamics suggest that immobilization of inflammatory proteins on solid scaffolds or molecular carriers may stabilize protein structure and preserve or amplify protein function. It is unknown if these mechanisms are operative in EBP adsorbent treatments. If these mechanisms are operative, then the adsorbent medium could become reactive, promoting inflammatory activity which could result in negative outcomes. Considering the recent reports of harm with adsorbent treatments in diverse inflammatory conditions, caution urges investigation of these potentially harmful mechanisms in these devices. Candidate mechanisms for possible inquiry are discussed.

Positive fortune telling enhances men's financial risk taking.

Fortune telling is a widespread phenomenon, yet little is known about the extent to which people are affected by it-including those who consider themselves non-believers. The present research has investigated the power of a positive fortune telling outcome (vs. neutral vs. negative) on people's financial risk taking. In two online experiments (n1 = 252; n2 = 441), we consistently found that positive fortune telling enhanced financial risk taking particularly among men. Additionally, we used a real online gambling game in a lab setting (n3 = 193) and found that positive fortune telling enhanced the likelihood that college students gambled for money. Furthermore, a meta-analysis of these three studies demonstrated that the effect of positive fortune telling versus neutral fortune telling was significant for men, but virtually absent for women. Thus, positive fortune telling can yield increased financial risk taking in men, but not (or less so) in women.

Lower class people suffered more (but perceived fewer risk disadvantages) during the COVID-19 pandemic.

Does COVID-19 affect people of all classes equally? In the current research, we focus on the social issue of risk inequality during the early stages of the COVID-19 pandemic. Using a nationwide survey conducted in China (N = 1,137), we predicted and found that compared to higher-class individuals, lower-class participants reported a stronger decline in self-rated health as well as economic well-being due to the COVID-19 outbreak. At the same time, we examined participants' beliefs regarding the distribution of risks. The results demonstrated that although lower-class individuals were facing higher risks, they expressed lesser belief in such a risk inequality than their higher-class counterparts. This tendency was partly mediated by their stronger endorsement of system-justifying beliefs. The findings provide novel evidence of the misperception of risk inequality among the disadvantaged in the context of COVID-19. Implications for science and policy are discussed.

Outcomes of lung transplantation at a Canadian center using donors declined in the United States.

OBJECTIVES: Donor lungs from the United States can be offered by US organ procurement organizations to Canada if no American centers accept them. The purpose of this study is to evaluate outcomes of patients undergoing transplant at a single center in Canada using declined lungs from the United States and to compare these outcomes to patients receiving lungs from Canadian donors. METHODS: A single-center retrospective review of recipients receiving lung transplantation between January 2009 and October 2019 was performed. An Organ Procurement and Transplantation Network standard transplant analysis and research-limited dataset as of August 17, 2021, was provided by the United Network for Organ Sharing. De-identified patient-level data were extracted from the standard transplant analysis and research file to identify lung offers made by US organ procurement organizations, declined by US lung centers, and transplanted by the University Health Network within the study time frame. We divided the analysis into 2 groups: recipients receiving donor lungs from Canada and recipients receiving donor lungs from the United States. Donor and recipient characteristics between the 2 groups were compared. Primary end point was proportional survival over a 10-year period. Secondary end points included 30-day mortality, intensive care unit and hospital length of stay, severe primary graft dysfunction, and incidence of chronic lung allograft dysfunction. RESULTS: During the study period, 1424 lung transplants were performed at our center. Of these, 124 (8.7%) were performed using donors from the United States. The incidence of transplants using US donors increased from 5% (5 out of 102) in 2009 to 15% (30 out of 200) in 2018. US donors were younger (aged 41 vs 47 years; P = .004), less likely to be from donors after cardiac death (9.6% vs 20%; P = .008), had higher use of ex vivo lung perfusion (EVLP, 46% vs 27%; P = .0002), and higher incidence of positive nucleic acid test for hepatitis C (16% vs 0.7%; P = .0001). Although the incidence of EVLP utilization was higher in the US lungs versus Canada lungs, more than half of US lungs (54%) proceeded directly to transplantation. Similar short- and long-term outcomes were observed between the 2 groups, including overall survival (hazard ratio, 1.12; 95% CI, 0.85-1.47; P = .40) CONCLUSIONS: Lung transplantation using donor lungs declined by multiple centers in the United States resulted in similar short- and long-term outcomes compared with donor lungs offered in Canada.

Perceiving societal pressure to be happy is linked to poor well-being, especially in happy nations.

Happiness is a valuable experience, and societies want their citizens to be happy. Although this societal commitment seems laudable, overly emphasizing positivity (versus negativity) may create an unattainable emotion norm that ironically compromises individual well-being. In this multi-national study (40 countries; 7443 participants), we investigate how societal pressure to be happy and not sad predicts emotional, cognitive and clinical indicators of well-being around the world, and examine how these relations differ as a function of countries' national happiness levels (collected from the World Happiness Report). Although detrimental well-being associations manifest for an average country, the strength of these relations varies across countries. People's felt societal pressure to be happy and not sad is particularly linked to poor well-being in countries with a higher World Happiness Index. Although the cross-sectional nature of our work prohibits causal conclusions, our findings highlight the correlational link between social emotion valuation and individual well-being, and suggest that high national happiness levels may have downsides for some.

Human Cooperation and the Crises of Climate Change, COVID-19, and Misinformation.

Contemporary society is facing many social dilemmas-including climate change, COVID-19, and misinformation-characterized by a conflict between short-term self-interest and longer-term collective interest. The climate crisis requires paying costs today to reduce climate-related harms and risks that we face in the future. The COVID-19 crisis requires the less vulnerable to pay costs to benefit the more vulnerable in the face of great uncertainty. The misinformation crisis requires investing effort to assess truth and abstain from spreading attractive falsehoods. Addressing these crises requires an understanding of human cooperation. To that end, we present (a) an overview of mechanisms for the evolution of cooperation, including mechanisms based on similarity and interaction; (b) a discussion of how reputation can incentivize cooperation via conditional cooperation and signaling; and (c) a review of social preferences that undergird the proximate psychology of cooperation, including positive regard for others, parochialism, and egalitarianism. We discuss the three focal crises facing our society through the lens of cooperation, emphasizing how cooperation research can inform our efforts to address them.