RESUMO
The article deals with factors causative of high social-economic importance of occupational skin diseases, presents parameters of occupational skin diseases prevalence, exogenous and endogenous risk factors of occupational skin diseases. This conditions appear to have negative influence on everyday life and occupational activities of the patients, induce lower quality of life and work performance. Pathogenesis and clinical signs, laboratory values characterizing atopic and allergic dermatitis are discussed. The authors necessitated a search of signs or complex of signs, that can point to predisposition for sensitization of individuals exposed to occupational hazards.
Assuntos
Dermatite Ocupacional/epidemiologia , Exposição Ocupacional/efeitos adversos , Dermatopatias/epidemiologia , Dermatite Atópica/epidemiologia , Dermatite Atópica/etiologia , Dermatite Atópica/fisiopatologia , Dermatite Ocupacional/fisiopatologia , Humanos , Prevalência , Qualidade de Vida , Fatores de Risco , Dermatopatias/etiologia , Dermatopatias/fisiopatologia , Fatores SocioeconômicosRESUMO
Evaluation of lipid peroxidation in patients with occupational allergic dermatoses revealed activation of free radical oxidation. Serum levels of diene conjugates and end products of free radical lipid peroxidation appeared to be informative parameters for assessing influences on body system and for estimating the disease severity and the individual protective means efficiency.
Assuntos
Indústria Química , Dermatite Ocupacional/metabolismo , Peroxidação de Lipídeos/fisiologia , Exposição Ocupacional/efeitos adversos , Adulto , Antioxidantes/metabolismo , Antioxidantes/intoxicação , Dermatite Ocupacional/sangue , Dermatite Ocupacional/classificação , Feminino , Sequestradores de Radicais Livres/metabolismo , Sequestradores de Radicais Livres/intoxicação , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Fatores de Tempo , Recursos HumanosRESUMO
Evaluating efficiency of individual skin protective means, the author used complex of clinical and laboratory methods with consideration of etiopathogenetic mechanism underlying occupational allergic dermatosis.
Assuntos
Dermatite Ocupacional/prevenção & controle , Níquel/efeitos adversos , Pomadas/uso terapêutico , Anticorpos/imunologia , DNA de Cadeia Simples/genética , Dermatite Ocupacional/genética , Dermatite Ocupacional/imunologia , Humanos , Peroxidação de Lipídeos , Nucleossomos/genética , Nucleossomos/imunologiaRESUMO
OBJECTIVE: To compare two strategies of patient recruitment, waiting room (WR) screening and screening after physician referral (PR), for participation in a treatment-outcome study of minor depression and dysthymia in primary care. The influence of demographic factors on patients' refusal to participate in WR screening was also examined. METHOD: Of a convenience sample of 3,344 first stage patients, a total of 609 patients were evaluated in a semi-structured manner using a two-stage screening procedure from the mood module of the Primary Care Evaluation of Mental Disorders (PRIME-MD). RESULTS: Male and older patients were more likely to refuse participation in screening than female and younger patients. Waiting room screens yielded a higher number of qualified patients compared to PR screens, but PR screens yielded a higher percentage of patients who qualified for further participation. CONCLUSIONS: The recruitment of male and older primary care patients is complicated by their tendency to refuse participation in WR screening for a treatment-outcome study of milder depression. Although each recruitment strategy offers advantages and disadvantages, the simultaneous use of both is recommended to recruit the most patients in the least amount of time.