RESUMO
BACKGROUND AND STUDY AIMS: Esophageal squamous papilloma (ESP) is a rare lesion. The aims of this study were to assess the prevalence of ESP in northeastern France and the risk of associated squamous cell carcinoma (SCC). PATIENTS AND METHODS: The charts of 78 patients who were diagnosed with ESP between January 2005 and February 2013 at three hospitals in northeastern France were reviewed. RESULTS: A total of 55â305 endoscopies were performed and 78 ESP were diagnosed (0.01â%). Patients with ESP included 44 males (56.4â%), 34 females (43.6â%); median age 50, interquartile range (IQR) 19â-â86.âMedian follow-up was 21 months (IQR 0â-â91 mo) and median time between first and second endoscopy was 7 months (IQR 0.5â-â74 mo). Of the total number of patients, 35 (44.9â%) had a second endoscopy. Main endoscopy indication was dyspepsia (24.4â%). Most ESP were isolated (93.6â%) and located at distal esophagus (27âcm, IQR 16â-â40âcm). Median size was 3âmm (IQR 1â-â20âmm). ESP-associated endoscopic lesions were hiatal hernia in 12 patients and esophagitis in 11 patients. Endoscopic treatment was mainly excisional biopsies (60.3â%). Human papillomavirus (HPV) was not detected in the 6 patients with available data. Low dysplasia was found in 2 ESP. During follow-up endoscopies, 2 SCC were detected in 2 different patients; the first SCC was located at the previous resection site of the ESP and the second had a different location. Prevalence of associated cancer was 1.3â%. CONCLUSION: Prevalence of ESP in northeastern France is similar to that previously reported. Endoscopic findings were also broadly the same as in previous reports. The occurrence of dysplasia and SCC should strongly encourage the endoscopist to totally remove the ESP and to start an endoscopic surveillance, given the potential risk of malignant transformation.