Fracture of Contemporary Femoral Stems: Common Trends in This Rare Occurrence.

BACKGROUND: Fracture of contemporary femoral stems is a rare occurrence in total hip arthroplasty. A knowledge gap remains regarding manufacturing, patient, and surgeon factors that may contribute to the increased risk of this complication. METHODS: We analyzed 13 contemporary fractured porous-coated femoral stems of various designs to determine cause and contributing factors of mechanical failure. Cases included 12 men and 1 woman who had an average age at index surgery of 53 years (range, 34 to 76 years). There were 10 of 13 patients who had a body mass index more than 30 (obese); 3 of the 10 had a body mass index more than 40. The mean time to fracture was 7.6 years (range, 7 months to 12 years). RESULTS: There were 4 titanium alloy stems that fractured an average of 3.6 years postrevision surgery for head/cup exchange and had associated iatrogenic mechanical and electrocautery damage to the femoral neck at fracture initiation sites. There were 6 modular stems that failed at the stem-sleeve or stem-neck interfaces with evidence of fretting corrosion. For 2 stem-neck fractures, mismatched head/stem combinations from different manufacturers resulted in untested mechanical offsets and loading. There were 2 proximal neck fractures and 1 mid-shaft fracture of coated cobalt-chromium alloy stems that occurred in 3 obese men. The neck fractures (10 to 12 years) were well-fixed stems. Lack of proximal fixation contributed to the mid-shaft fracture (7 months). CONCLUSION: While rare, femoral stem fractures pose catastrophic outcomes in primary and revision total hip arthroplasty. Manufacturing, patient, and surgical factors contributing to stem failures were identified, including patient obesity, heat-treatment reduction of mechanical properties, iatrogenic implant damage, and mixing of different vendor stems and heads.

Stem Cells and Platelet-rich Plasma for Knee Osteoarthritis: Prevalence and Cost in South Florida.

INTRODUCTION: The use of stem cell therapy (SCT) and platelet-rich plasma (PRP) injection for knee osteoarthritis (OA) is extremely controversial and at best experimental stage. These treatments are being offered across the nation for "cash-only payments." Our objectives were to determine (1) what proportion of board-certified orthopedic surgeons in Miami-Dade County offer SCT or PRP and (2) how much do practices charge for these services. METHODS: All board-certified orthopedic surgeons' offices in Miami-Dade County were identified by their American Academy of Orthopaedic Surgeons active membership. Offices were contacted and presented a hypothetical patient with end-stage OA searching for treatment (SCT or PRP injections) before having to undergo surgery. RESULTS: Of the 96 registered American Academy of Orthopaedic Surgeons member's offices, 91 (94.7%) were contacted, 36% of offices offered PRP, and 24.5% offered SCT. However, 81% of the offices were transparent on the pricing of PRP, whereas 42% gave a price for SCT. Remaining practices stated that pricing would be "determined or discussed" during a scheduled visit. Mean cost for PRP injection was $897 (range, $350 to $1,700), and for SCT injection, it was $3,100 (range, $1,200 to $6,000). DISCUSSION: Biological injectables as treatment of knee OA have potential use in the nonsurgical management of this disease. Data on the effectiveness are lacking and are conflicting. Data should continue to be investigational. LEVEL OF EVIDENCE: Level IV.

Rehabilitation Outcomes for Total Knee Arthroplasties: Continuous Adductor Canal Block Versus Continuous Femoral Nerve Block.

OBJECTIVE: To determine whether any strength, range of motion (ROM), or functional improvement exists in the adductor canal block (ACB) group after completion of inpatient rehabilitation and following the removal of the continuous block. DESIGN: Retrospective cohort. SETTING: Inpatient rehabilitation at discharge and outpatient orthopedic clinic for follow-up. PARTICIPANTS: Two hundred forty-six consecutive primary total knee arthroplasties (TKAs; N = 221 patients) performed by a single surgeon in a single institution between July 2013 and August 2015 for a diagnosis of osteoarthritis. INTERVENTIONS: All TKA cases received a continuous femoral nerve block (FNB) from July 2013 to August 2014 for postoperative pain control. From August 2014 through August 2015, all TKAs received a continuous ACB. MAIN OUTCOME MEASURES: Manual muscle tests (MMTs; 0-5 scale) of the quadriceps and passive ROM of the knee were assessed at 3 time periods (hospital discharge [HD], 1-2 weeks, and 1 month). Patient-oriented outcomes and clinical knee scores were examined preoperatively and postoperatively at 3 and 6 months. RESULTS: 63.6% of FNB cases had an MMT less than 3 at HD and 36.4% of FNB cases had an MMT of 3 or greater at HD. Conversely, 46% of ACB cases had an MMT less than 3 at HD and 54% had an MMT of 3 or greater at HD. There were no statistically significant differences in all postoperative variables at all tested time periods. CONCLUSIONS: This study showed no short-term postoperative advantages in the ACB group after catheter removal. The superior inpatient rehabilitation course in the continuous ACB group is likely not long enough to translate into any maintained benefit following catheter removal. Nevertheless, the trend toward greater strength in the ACB group in the immediate short term at HD warrants further investigation.

Cultural Biases in Current Medical Practices with a Specific Attention to Orthopedic Surgery: a Review.

Due to the increasing diversity within the United States population, there is an ever-increasing need for increased education on cultural literacy and tolerance in medical schools and residency programs. The purpose of this article was to review how a person's culture can play a substantive role in effecting and influencing (1) medical diagnosis, (2) patient and health provider medical decision-making, (3) the patient's perception of disease, and (4) the doctor-patient relationships. Many of the decisions we make as orthopedic surgeons must account for the patient's cultural needs, as much of our work impacts patients' daily activities and function. When considering the patient's perception of disease, validated tools have been developed, such as the Patient-Specific Index, which can be used to assess the feelings, goals, and expectations of patients. Cultural competency should be a part of curricula at every level of medical education.

Primary Total Knee Arthroplasty: How Does Residual Patellar Thickness Affect Patient-Oriented Outcomes?

BACKGROUND: Maintenance of the native patellar thickness has been deemed important for proper clinical outcomes after total knee arthroplasty (TKA). Our objective was to study the effects of the change in patellar thickness on patient-perceived outcomes (PPOs) after TKA. We hypothesized that reestablishing native patellar thickness after TKA results in better PPOs. METHODS: 819 consecutive patients undergoing primary TKA were studied. Patients were classified according to their postoperative patellar thickness into: (1) less than native patella thickness; (2) equal to native patella thickness; and (3) greater than native patella thickness. Difference in postoperative range of motion (ROM), PPOs and clinical scores, and delta-Δ-change were assessed. MANCOVA was used to assess for differences. RESULTS: No significant differences found based on postoperative patellar thickness (mean follow-up: 4.9 ± 2.1 years) for each ROM assessments. Those who reported more stiffness (Western Ontario and McMaster Universities Arthritis Index stiffness; P = .011) and lower knee active flexion (P = .046) preoperatively had "greater than native patella thickness" after surgery. Postoperatively, the "equal to native patella thickness" group reported significantly better quality of life (quality of well-being scale 7 total; P = .008) as well as better physical score (Short Form-36 role physical score; P = .03). The amount of improvement (delta-Δ-change), when restoring patellar thickness equal to the native demonstrated greatest improvements in quality of life (quality of well-being scale 7 total; P = .016) physical measures (Short Form-36 role physical [P = .025], and Western Ontario and McMaster Universities Arthritis Index stiffness scores [P = .006]). CONCLUSION: When compared with the native patellar thickness, a final postoperative difference (delta thickness) that ranges from -1.06 to 2.58 mm provides satisfactory results and does not seem to affect ROM after surgery.

Prolonged Conservative Management in Total Joint Arthroplasty: Harming the Patient?

BACKGROUND: It is important to understand the long-term consequences of postponing total joint arthroplasty until the onset of severe functional impairment. Therefore, the purpose of this investigation was to determine and compare the midterm to long-term postoperative outcomes of patients who underwent total joint arthroplasty with severe vs less severe preoperative functional impairment. METHODS: A total of 105 primary unilateral total hip/knee arthroplasty patients were studied. Patients were divided into 2 groups-severely functionally impaired (preoperative Western Ontario and McMaster Osteoarthritis Index function ≥51 points) and functionally impaired (preoperative Western Ontario and McMaster Osteoarthritis Index function <51 points). RESULTS: At an average of 11.2 years postoperatively, the patients who were severely functionally impaired preoperatively had worse outcomes than did the patients with less severe preoperative functional impairment. CONCLUSION: Our data suggest that, after surgery, it is unlikely that patients who are severely functionally impaired preoperatively will ever catch up to patients who have the surgery with less severe functional impairment.

Preoperative Glycemic Control on Total Joint Arthroplasty Patient-Perceived Outcomes and Hospital Costs.

BACKGROUND: The purpose of this study was to determine the influence of preoperative glycemic control in diabetic patients undergoing a primary total hip or knee arthroplasty. We wanted to study patient-perceived outcomes in the medium term, the length of stay, hospital costs, and rate of short-term postoperative complications. METHODS: One hundred twenty consecutive primary total joint arthroplasties (TJAs) performed in type 2 diabetic patients were stratified into 2 groups representing optimal and suboptimal preoperative glycemic control, based on serum levels of glycated hemoglobin (HbA1c), and those groups compared. RESULTS: The mean follow-up time was 5.9 years (range, 2.1-10.7 years). Both groups demonstrated improvement in all patient-perceived outcome measures after TJA, with no significant difference detected in any change of a measure between the groups. No significant difference was detected in the length of stay, hospital costs, or rate of short-term postoperative complications between the groups. CONCLUSION: Preoperative glycemic control in type 2 diabetic patients undergoing TJA did not affect patient-perceived outcomes in the medium term. Optimal vs suboptimal glycemic control in these patients also had no effect on the length of stay, hospital costs, or rate of short-term postoperative complications.

Total Joint Arthroplasty: A Granular Analysis of Outcomes in the Economically Disadvantaged Patient.

BACKGROUND: Poor patients experience more serious complications and worse outcomes after surgery than higher-income patients. Our objective was to study detailed patient sociodemographic characteristics and preoperative/postoperative patient-oriented outcomes in economically disadvantaged and non-economically disadvantaged primary total joint arthroplasty patients. METHODS: From a consecutive series, 213 economically disadvantaged patients and 1940 non-economically-disadvantaged patients were statistically analyzed. Baseline sociodemographic characteristics and pain visual analog scale, Quality of Well-Being Index 7, Short Form 36, and Western Ontario and McMaster Universities Arthritis Index scores recorded before and after surgery were compared between both groups controlling for baseline differences. Minimum follow-up was 1 year. RESULTS: Economically disadvantaged patients were significantly younger, more likely to be disabled, and had worse preoperative and postoperative scores. CONCLUSION: When compared with non-economically disadvantaged patients, economically disadvantaged patients consistently had lower function and worse quality of life before and after total joint arthroplasty.

Preventing Leg Length Discrepancy and Instability After Total Hip Arthroplasty.

Restoration of equal leg lengths and dynamic hip stability are essential elements of a successful total hip arthroplasty. A careful clinical examination, a preoperative plan, and appropriate intraoperative techniques are necessary to achieve these goals. Preoperative identification of patients at risk for residual leg length discrepancy allows surgeons to adjust the surgical approach and/or the type of implant and provide better preoperative patient education. The use of larger femoral heads, high-offset stem options, and enhanced soft-tissue repairs have improved impingement-free range of motion as well as dynamic hip stability and have contributed to an overall reduction in dislocation. Methods for accurate leg length restoration and component positioning include anatomic landmarks, intraoperative radiographs, intraoperative calipers, stability testing, and computer-assisted surgery. If recurrent instability occurs after total hip arthroplasty, the underlying cause for dislocation should be identified and treated; this may include the use of semiconstrained dual-mobility or fully constrained liners, depending on abductor function. Surgeons should be aware of the clinical and surgical techniques for achieving leg length equalization and dynamic hip stability in total hip arthroplasty.

Update on Biomaterials.

Biomaterials are essential to the use and development of successful treatments for orthopaedic patients. Orthopaedic surgeons need to understand the expected clinical performance and the effects of implants in patients. Recent attempts to improve implant durability have resulted in adverse effects related to biomaterials and their relationship to patients. Examples of these adverse effects in hip arthroplasty include wear and corrosion of metal-on-metal bearings, trunnions, and tapered modular neck junctions. Conversely, polymers and ceramics have shown substantial improvements in durability. Improved implant compositions and manufacturing processes have resulted in ceramic head and acetabular liners with improved material properties and the avoidance of voids, which have, in the past, caused catastrophic fractures. Cross-linking of polyethylene with radiation and doping with antioxidants has substantially increased implant durability and is increasingly being used in joint prostheses other than the hip. Additive manufacturing is potentially a transformative process; it can lead to custom and patient-specific implants and to improvements in material properties, which can be optimized to achieve desired bone responses. Orthopaedic surgeons must understand the material properties and the biologic effects of new or altered biomaterials and manufacturing processes before use. In addition, a clear benefit to the patient must be proven based on superior preclinical results and high-quality clinical investigations before orthopaedic surgeons use new or altered biomaterials.

Bilateral atypical femoral fracture and end-stage arthritis of the hip, treated with total hip arthroplasty.

The prolonged use of bisphosphonates has been associated with an increased rate of atypical femoral fracture. A 77-year-old woman with prolonged bisphosphonate use presented to our office with groin pain and end-stage arthritis, She was scheduled for a total hip replacement. Before the surgery and with minimal trauma, the patient then suffered a displaced atypical femoral fracture. She underwent a total hip replacement as a treatment for her fracture and her arthritis. Subsequently, the patient presented with pain in the contralateral thigh with an incomplete atypical femoral fracture. That side was also treated with a total hip arthroplasty. An uncemented stem with open reduction internal fixation and a long cemented stem were used on the complete fracture and incomplete fracture sides, respectively. At a follow-up of 2 years, the patient had no pain and had excellent function demonstrating the short-term success of both cemented and uncemented stems in total hip arthroplasty after atypical femoral fractures.

High Rates of Interest in Sex in Patients With Hip Arthritis.

BACKGROUND: Being sexually active has been associated with a high quality of life. Unfortunately, the topic of sexual limitations in patients undergoing total hip arthroplasty (THA) has not been well studied. QUESTION/PURPOSES: (1) What proportion of patients experience sexual limitations because of hip arthritis before THA; (2) whether patient reports of sexual limitations would be associated with poorer results on general health and hip-specific instruments; and (3) whether patient reports of sexual limitations would be associated with poorer preoperative range of motion. METHODS: Between May 19, 2003, and August 17, 2009, 403 patients (423 hips) underwent primary THA; of those, 237 patients/hips (59% [237 of 403]) had addressed the new patient questionnaire within 1 year before surgery and had it available for review; and of those, 192 (48% [192 of 403]) had answered the question about sexual function on their questionnaire. This group included 159 patients who were sexually active (82% [159 of 192]). These patients were defined as our study cohort. Among them, 131 patients (82% [131 of 159]) reported some degree of sexual limitations and 28 patients (18% [28 of 159]) did not report limitations. Patient characteristics evaluated included baseline demographics, body mass index, American Society of Anesthesiologists, Charlson in addition to preoperative/postoperative pain intensity/frequency (visual analog scale, 0-10), SF-36, WOMAC, and baseline hip range of motion measures. Outcomes of interest were compared between both groups. Mean age was 65 years. Chi-square, t-tests, and multivariate analysis of variance were used. Alpha was set at 0.05. RESULTS: Hip arthritis interfered with the sexual life of 82% (131 of 159) of sexually active patients, more so in women than men (96% [68 of 71], versus 72% [63 of 88]; odds ratio, 8.99; 95% confidence interval, 2.588-31.258; p = 0.001). Preoperatively, patients with sexual limitations had a mean pain intensity of 8 ± 1.84 points on the visual analog scale, whereas patients without limitations had 6 ± 1.99 points (p < 0.001). Differences were also found in WOMAC pain (11 ± 3.9 versus 8 ± 3.5; p = 0.004) and WOMAC stiffness (3.4 ± 2.3 versus 1.4 ± 1.7; p = 0.001). Baseline hip flexion (84° ± 22.4° versus 93° ± 16.5°, respectively; p = 0.04) and external rotation (23° ± 14.5° versus 30° ± 11.6°; p = 0.02) were also different. CONCLUSIONS: Our data suggest that many patients getting a hip arthroplasty are sexually active but most patients who are sexually active have sexual limitations before surgery as a result of hip arthritis. Women are more affected than men. Patients with these limitations experience more pain and have less flexion and external rotation before surgery. Preoperatively, counseling on sexual activities should be routinely discussed with all patients undergoing THA. LEVEL OF EVIDENCE: Level III, prognostic study.

Racial Disparities in Lower Extremity Arthroplasty Outcomes and Use.

Race-associated disparities often occur in patients who undergo lower extremity total joint arthroplasty (TJA). Although it is imperative to elucidate and describe the disparities in race and ethnicity that may influence patient perception, satisfaction, and surgical outcomes, there is a paucity of reports detailing the nature of potential racial disparities in TJA. Therefore, the purpose of this review was to examine racial and ethnic disparities in the (1) physician-patient relationship; (2) use of TJA; (3) intraoperative and 30-day postoperative complications; and (4) patient-reported outcomes. Although there are limited studies that evaluated this topic, it has been shown that there are race-specific differences in physician-patient relationships. Specifically, African American patients report lower satisfaction rates in communication with their physician than their Caucasian counterparts and physicians were more apt to describe African Americans as less "medically cooperative." The majority of the studies the authors found regarding TJA use indicated that African Americans and Hispanics were less likely to undergo lower extremity TJA than Caucasians. Furthermore, racial minorities may have higher 30-day readmission and intra- and postoperative complication rates compared with Caucasians. Despite these compelling findings, concrete conclusions are difficult to make due to the presence of multiple confounding patient factors, and more studies examining the racial and ethnic disparities in patients with TJA are needed.

Does Race Affect Outcomes in Total Joint Arthroplasty?

BACKGROUND: Several studies suggest worse surgical outcomes among racial/ethnic minorities. There is a paucity of research on preoperative and postoperative pain, general health, and disease-specific measures in which race is the main subject of investigation; furthermore, the results are not conclusive. QUESTIONS/PURPOSES: (1) Do black patients have more severe or more frequent preoperative pain, well-being, general health, and disease-specific scores when compared with white patients? (2) Are there differences between black patients and white patients after hip or knee arthroplasty on those same measures? METHODS: In this retrospective study, we used an institutional arthroplasty registry to analyze data on 2010 primary arthroplasties (1446 knees and 564 hips) performed by one surgeon at a single institution. Cases from patients self-identifying as black (n = 105) and white (n = 1905) were compared (controlling for confounders, including age and ethnicity) on the following preoperative and postoperative patient-oriented outcomes: pain intensity/frequency as measured by a visual analog scale (VAS), Quality of Well-Being (QWB-7), SF-36, and WOMAC scores. T-tests, chi square, and multivariate analysis of covariance were used. Alpha was set at 0.05. Postoperative analysis was performed only on those cases that had a minimum followup of 1 year (mean, 3.5 years; range, 1-9 years). Of the 2010 arthroplasties, 37% (39 of 105) of those cases performed in black patients and 64% (1219 of 1905) of those performed in white patients were included in the final postoperative model (multivariate analysis of covariance). RESULTS: Black patients had more severe preoperative pain intensity (VAS: 8 ± 1.8 versus 8 ± 2.0, mean difference = 0.76 [95% confidence interval {CI}, 0.34-1.1], p < 0.001). Black patients also had worse well-being scores (QWB-7: 0.527 ± 0.04 versus 0.532 ± 0.05, mean difference = -0.01 [CI, -0.02 to 0.00], p = 0.037). Postoperatively, pain intensity (VAS: 1 ± 3.1 versus 1 ± 1.8, mean difference= 0.8 [CI, 0.19-1.4], p= 0.010) and (QWB-7: 0.579 ± 0.09 versus 0.607 ± 0.11, mean difference= -0.049 [CI, -0.08 to -0.01], p = 0.008) were different but without clinical significance. CONCLUSIONS: Black patients underwent surgery earlier in life and with different preoperative diagnoses when compared with white patients. Black patients had worse preoperative baseline pain, well-being, general health, and disease-specific scores as well as worse postoperative scores. However, these differences were very narrow and without clinical significance. Notwithstanding, the relations of race with outcomes remain complex. Further investigations to recognize disparities and minimize or address them are warranted. LEVEL OF EVIDENCE: Level III, prognostic study.

Total hip arthroplasty in the treatment of osteonecrosis of the femoral head: then and now.

The objective of this review is to summarize and analyze the survivorship and the reported results of the use of total hip arthroplasty (THA) in patients with osteonecrosis of the femoral head. In the past, THA was thought to have poor survivorship and poor clinical and radiological results in patients with this diagnosis. However, more recent reports have suggested an improvement in the survivorship, radiological results, and outcomes of THAs when performed for this condition. Surgeons have incorporated THA into their practice patterns to the point that an increasing percentage of patients with this particular diagnosis are currently being treated with it. When collapse and/or arthrosis of the necrotic femoral head are present, THA seems to be the most reliable and proven option for its treatment.

A current review of core decompression in the treatment of osteonecrosis of the femoral head.

The review describes the following: (1) how traditional core decompression is performed, (2) adjunctive treatments, (3) multiple percutaneous drilling technique, and (4) the overall outcomes of these procedures. Core decompression has optimal outcomes when used in the earliest, precollapse disease stages. More recent studies have reported excellent outcomes with percutaneous drilling. Furthermore, adjunct treatment methods combining core decompression with growth factors, bone morphogenic proteins, stem cells, and bone grafting have demonstrated positive results; however, larger randomized trial is needed to evaluate their overall efficacy.

Readmission Rates in Total Hip Arthroplasty: A Granular Analysis?

A deeper understanding of readmissions in arthroplasty is warranted. We wanted to determine in primary THA patients: readmission rates; baseline characteristics of patients with/without readmissions; and readmission reasons. 201 consecutive patients were studied. Preoperative characteristics, patient-perceived-outcomes, and hip-scores were compared between patients with and without readmissions. Rates were 1% (readmitted n=2; 15-days), 3.5% (7; 30-days), 6.5% (13; 90-days), and 16.9% (34; 1-year). Readmitted patients had significantly worse preoperative comorbidities/outcome-scores when compared to non-readmitted patients. "Surgical-site infection" was the most frequent readmission reason within 30/90days. Within 1year, it was another elective joint. Fifty percent of readmissions were not related to the index-surgery (15-days). Preoperative health status affects rates. Many rehospitalizations are not related to the index-surgery and probably unpreventable.

The Cost-Utility of Total Hip Arthroplasty: Earlier Intervention, Improved Economics.

We estimated the cost of Quality-Adjusted-Life-Years gained according to preoperative disease severity. We studied 159 primary unilateral THA, mean follow-up: 4 years. A median split of preoperative WOMAC scores was done to set apart a low (better) and a high (worse) score group. The groups with worse preoperative WOMAC were consistently associated with a less cost-effective intervention. The highest mean cost-effectiveness was achieved by patients with better WOMAC-total ($8256.32/QALY-gained). As patients aged, the cost-effectiveness of THA decreased. Patients 75 years of age or older and with worse scores had the least cost-effective interventions ($25,937.33/QALY-gained). THA remains a very cost-effective intervention even when performed in older "sicker" patients. Waiting for the patient to deteriorate will make the intervention more "expensive".