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1.
Environ Sci Pollut Res Int ; 29(2): 1729-1745, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34705203

RESUMO

The acoustical properties of a barrier are highly dependent on the physical properties of the material and the internal structure of the material. The acoustical material can curtail the quality of sound or enhance the dispersion, depending on the application being considered. The efficient acoustic performance of noise barriers possessing different shapes and materials including waste materials is reviewed for field implementation to achieve the low-cost sustainable noise barrier application in the Indian context. The review analysis of research papers demonstrates that the acoustic performance of barriers is dependent on different shapes, materials, and textures as well as onsite geometry. Based on the review study, T-shaped barriers with a soft top surface are found to be efficient at noise attenuation. For transparent barriers, perceived loudness and noise annoyance are assessed lower than that for opaque barriers and utilization of waste materials viz. plastic, rubber, bottom coal ash, etc. gives high noise attenuation along with low-cost efficiency. Noise pollution levels are high from prescribed noise limits in most of the Indian metropolitan cities. The Indian government is working on mitigation strategies of noise pollution as well as abiding laws regarding noise standards for the zone (residential, industrial, commercial, and silences) wise. In contrast, some communities which are adjacent to roads are suffering from high noise levels in the ambience. Therefore, it requires a coherent strategy for long-term measures intended at minimizing exposure of noise hence providing much more comfort to live, work, and shop near high-traffic roads. Noise barriers are highly beneficial in mitigating the emitted noise from the traffic.


Assuntos
Ruído dos Transportes , Acústica , Cidades , Cinza de Carvão , Exposição Ambiental
2.
Environ Sci Pollut Res Int ; 27(30): 38311-38320, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32623675

RESUMO

Noise is considered as an underrated and underemphasized pollutant in contrast to other pollutants of the environment. Due to the non-acute response of health effects, people are not vigilant towards consequences regarding noise pollution. The expansion of the transportation industry is contributing towards the increment in the public and private vehicular volume which causes an increment in noise pollution. For evaluation of respective scenario, the research study has been conducted on one of the minor roads of Nagpur, India; for 2 years, viz., 2012 and 2019. The study concludes an increment of 5-6 dB(A) in noise level, 4-6 times in honking, and 1.7 times in traffic volume. The study confirms increment in sound pressure by 65.9% and 81.9% for the year 2012 and 2019 during morning and evening sessions, respectively. Noise prediction model has also been developed for the abovementioned years, using multiple regression analysis, considering traffic volume, honking, and speed against noise equivalent level. Honking has been further characterized into honk by light and medium category vehicles as acoustical properties of horns vary with respect to category of vehicle and introduced into the noise prediction model. Noise prediction model for 2019 has predicted the noise level in a range of - 1.7 to + 1.4 dB (Leq) with 84% of observations in the range of - 1 to + 1 dB (Leq), when compared with observed Leq on the field. For proper management of noise pollution, a noise prediction model is essentially needed so that the noise level can be anticipated, and accordingly, measures can be outlined and executed. This increased noise level has serious impacts on human hearing capacity and overall health. Accordingly, noise mitigation preventive measures are recommended to control traffic noise in the urban environment.


Assuntos
Ruído dos Transportes , Humanos , Índia , Análise de Regressão
3.
Environ Sci Pollut Res Int ; 26(36): 36812-36819, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31745771

RESUMO

Noise is one of the most significant sources of environmental pollution in metro cities. Traffic noise plays an important role to contribute to ambient noise pollution. Noise pollution monitoring was carried out using sound level meter mounted on the cycle with the help of mould fixed on it. Cycle is a noiseless mode of transport and therefore, it was used for noise monitoring over 700 locations in Nagpur City. Noise levels were recorded at each location for 5 min during peak rush hours of traffic in the morning and in the evening at an interval of 1 s leading to around 300 readings each. Noise indices like Leq, L90, L10, Lmax and Lmin were calculated for noise level data analysis. TNI was also determined for analysis of traffic noise on intersections of roads. Equivalent noise levels were transferred into the Geographic Information System (GIS) and spatial analysis tool was used to create spatial and strategic noise maps. Based on the maps, it is revealed that noise levels are exceeded all over the city with respect to ambient noise standards. It was experienced that intersections of roads during peak rush time are very noisy due to honking. The study recommends the noise monitoring through cycle-mounted sound level meter since it covers unapproachable sites, more coverage in the city that helps in identifying hotspot area of concern for noise abatement strategies and planning.


Assuntos
Monitoramento Ambiental , Ruído , Cidades , Poluição Ambiental , Índia , Análise Espacial
4.
Pharmacol Rep ; 71(3): 517-521, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31009843

RESUMO

BACKGROUND: Cyclic neucleotides are involved in many cellular functions including smooth muscle relaxation, inflammation, and signal transduction. Sildenafil and tadalafil are phosphodiesterase-5 (PDE-5) inhibitors which prevent the degradation of cyclic neucleotide i.e. guanosine 3',5' cyclic monophosphate (cGMP) and increase the levels of cGMP. In this study sildenafil and tadalafil were evaluated for their anti-inflammatory, anti-oxidative and anti-nitrosative stress potential in animal model of bronchial asthma. METHODS: Wistar rats were sensitized with 10 mg intraperitoneal (ip) ovalbumin adsorbed to 10 µg of aluminum hydroxide on day 0. Animals were given sildenafil (1 and 3 mg/kg ip) and tadalafil (1 and 3 mg/kg ip) from day 1 to day 14. Also, on day 14 animals were challenged with ovalbumin (1 mg ip). After 24 h, samples were collected to analyze interleukin-4 (IL-4) and tumour necrosis factor-α (TNF-α), in serum and bronchoalveolar lavage fluid (BALF). The oxidative stress markers malondialdehyde (MDA), reduced glutathione (GSH) and nitric oxide metabolites (NOx) were also measured in serum. RESULTS: Pre-treatment with sildenafil (1 and 3 mg/kg ip) and tadalafil (1 and 3 mg/kg ip) significantly reduced the levels of pro-inflammatory cytokines IL-4 and TNF-α in rat serum and BALF. In addition, pre-treatment with both the drugs decreased the levels of MDA and NOx and increased the levels of GSH in serum. CONCLUSIONS: Sildenafil and tadalafil decreased pro-inflammatory cytokines in serum and BALF. Both drugs inhibit oxidative and nitrosative stress in animal model of bronchial asthma and could have a therapeutic potential in bronchial asthma.


Assuntos
Asma/tratamento farmacológico , Brônquios/efeitos dos fármacos , Inflamação/tratamento farmacológico , Estresse Nitrosativo/efeitos dos fármacos , Estresse Oxidativo/efeitos dos fármacos , Citrato de Sildenafila/farmacologia , Tadalafila/farmacologia , Animais , Asma/metabolismo , Brônquios/metabolismo , Líquido da Lavagem Broncoalveolar/química , Citocinas/metabolismo , Modelos Animais de Doenças , Feminino , Glutationa/metabolismo , Inflamação/metabolismo , Pulmão/efeitos dos fármacos , Pulmão/metabolismo , Masculino , Malondialdeído/metabolismo , Óxido Nítrico/metabolismo , Ratos , Ratos Wistar
5.
Case Rep Dent ; 2013: 307096, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23555061

RESUMO

Liquid-supported denture technique allows continued adaptation of denture to the mucosa both at resting and functional state. A complete denture prosthesis is unacceptable if it violates the foundation on which it rests. In this case, a technique for fabrication of a complete denture prosthesis that eliminates the disadvantages of tissue conditioners and soft liners (i.e., poor bond strength to acrylic, candidal colonization, etc.) and preserves the remaining tissues is described. Liquid-supported denture can be a permanent solution to some patients with problematic conditions like diabetes, xerostomia, atrophied ridge, and so forth.

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