Assuntos
Carbapenêmicos/farmacologia , Infecções por Klebsiella/microbiologia , Klebsiella pneumoniae/enzimologia , Complicações Infecciosas na Gravidez/microbiologia , Resistência beta-Lactâmica , beta-Lactamases/biossíntese , Antibacterianos/farmacologia , Antibacterianos/uso terapêutico , Carbapenêmicos/uso terapêutico , Feminino , França , Humanos , Recém-Nascido , Infecções por Klebsiella/diagnóstico , Klebsiella pneumoniae/isolamento & purificação , Gravidez , Complicações Infecciosas na Gravidez/diagnóstico , TurquiaAssuntos
Efeitos Psicossociais da Doença , Infertilidade/terapia , Programas Nacionais de Saúde/economia , Técnicas Reprodutivas , França/epidemiologia , Humanos , Infertilidade/economia , Infertilidade/epidemiologia , Infertilidade/psicologia , Técnicas Reprodutivas/efeitos adversos , Técnicas Reprodutivas/economia , Técnicas Reprodutivas/psicologia , Fatores de RiscoRESUMO
BACKGROUND: This study was designed to determine the crude cumulative live-birth rates in a cohort initiating frozen donor semen treatment until completion. METHODS: This cohort study included 588 couples with primary infertility in one University Hospital centre. The treatment sequence involved first artificial insemination (AID) followed by IVF if necessary (IVF-D). Live birth, drop-out for personal or medical reasons and recourse to IVF-D were recorded for all patients. Live births and drop-out were expressed both as rates per cycle and crude cumulative rates. RESULTS: At the completion of AID and IVF-D cycles, 406 couples in the cohort (69%) achieved a live-birth and 182 couples (31%) discontinued treatment. In most cases, couples stopped treatment for personal reasons (74%) whereas fewer couples were denied further treatment for medical reasons (26%). CONCLUSIONS: This is the first report on the crude cumulative live-birth rate in a cohort after AID and IVF-D cycles. Although calculation based on crude cumulative live-birth rate shows lower results in comparison with life table analysis, this method allows patients to obtain an insight into their actual chances of achieving a successful pregnancy.
